PIMA542186

Cibisatamab Recombinant Human Monoclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542186-Each-of-1 In Stock ₹ 44,020.62

PIMA542186 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

Cibisatamab

Classification

Recombinant Monoclonal

Conjugate

Unconjugated

Gene Alias

CEA TCB; RG-7802; RO-6958688

Immunogen

Human CD3E/CEACAM5

Quantity

100 μg

Primary or Secondary

Primary

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Target Molecule

Chemical

Applications

ELISA, SDS-Page

Concentration

2.54 mg/mL

Formulation

PBS with no preservative; pH 7.4

Host Species

Human

Purification Method

Protein A

Regulatory Status

RUO

Target Species

Chemical

Product Type

Antibody

Isotype

IgG1 κ, IgG1 λ

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Description

  • Endotoxin level < 0.01EU/μg by LAL method Use a manual defrost freezer and avoid repeated freeze thaw cycles
  • Store at 2 to 8 °C for one week
  • Store at -20 to -80 °C for twelve months from the date of receipt
  • Cibisatamab (CEA-TCB) is a T cell bispecific antibody that binds carcinoembryonic antigen (CEA) on cancer cells and CD3 on T cells
  • Cibisatamab has a single CD3epsilon chain binding site and two CEA binding sites on T cells (it regulates the binding affinity to cancer cells with high expression of CEA on the cell surface)
  • This avoids targeting healthy epithelial cells with low CEA expression levels
  • T cell activation, cytokine secretion and release of cytotoxic particles are triggered by binding to CEA on the surface of cancer cells and CD3 on T cells.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA542186

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Antigen:
Cibisatamab

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene Alias:
CEA TCB; RG-7802; RO-6958688

Immunogen:
Human CD3E/CEACAM5

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Applications:
ELISA, SDS-Page

Concentration:
2.54 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Host Species:
Human

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 κ, IgG1 λ

Img

Thermo Scientific

PIMA542187

--


Antigen:
Iscalimab

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene Alias:
CFZ-533; NVP-CFZ533; OM11-62MF

Immunogen:
Human CD40/TNFRSF5

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Applications:
ELISA, SDS-Page

Concentration:
1.24 mg/mL

Formulation:
PBS with no preservative; pH 7.5

Host Species:
Human

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 κ

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Thermo Scientific

PIMA542191

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Antigen:
Etigilimab

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene Alias:
OMP-313M32

Immunogen:
Human TIGIT/VSTM3

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Applications:
ELISA, SDS-Page

Concentration:
1.41 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Host Species:
Human

Purification Method:
Protein A

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 κ

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PIMA542192

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Antigen:
Abrezekimab

Classification:
Recombinant Monoclonal

Conjugate:
Unconjugated

Gene Alias:
CDP7766; UCB-4144; VR-942

Immunogen:
Human IL13

Quantity:
100 μg

Primary or Secondary:
Primary

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Target Molecule:
Chemical

Applications:
ELISA, SDS-Page

Concentration:
1 mg/mL

Formulation:
PBS with no preservative; pH 7.4

Host Species:
Human

Purification Method:
Protein L

Regulatory Status:
RUO

Target Species:
Chemical

Product Type:
Antibody

Isotype:
IgG1 F(ab) κ