PIMA542793

AKT1/AKT2 Recombinant Rabbit Monoclonal Antibody (1G0K5), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA542793-Each-of-1 In Stock ₹ 44,020.62

PIMA542793 - Each of 1

₹ 44,020.62

In Stock

Quantity

1

Base Price: ₹ 44,020.62

GST (18%): ₹ 7,923.712

Total Price: ₹ 51,944.332

Antigen

AKT1/AKT2

Classification

Recombinant Monoclonal

Concentration

0.8 mg/mL

Formulation

PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.

P31749, P31750, P31751, P47196, P47197, Q60823

Gene Symbols

AKT1, AKT2

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 381-480 of human AKT1/2 (P31749).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

1G0K5

Conjugate

Unconjugated

Gene

AKT2

Gene Alias

AKT; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT1; AKT1m; AKT2; CWS6; HIHGHH; murine thymoma viral (v-akt) homolog-2; PKB; PKB alpha; PKB beta; PKB-ALPHA; PKBB; PKBBETA; PRKBA; PRKBB; Protein kinase Akt-2; Protein kinase B; Protein kinase B alpha; protein kinase B beta; Proto-oncogene c-Akt; putative v-akt murine thymoma viral oncoprotein 2; RAC; rac protein kinase alpha; rac protein kinase beta; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-BETA; RAC-beta serine/threonine-protein kinase; RAC-PK-alpha; RAC-PK-beta; serine-threonine protein kinase; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene-like protein 1

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11651, 11652, 207, 208, 24185, 25233

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

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Description

  • Positive test controls include: PC-12, PC-3, C2C12
  • Immunogen sequence: SGLLKKDPKQ RLGGGSEDAK EIMQHRFFAG IVWQHVYEKK LSPPFKPQVT SETDTRYFDE EFTAQMITIT PPDQDDSMEC VDSERRPHFP QFSYSASGTA AKT1 is one of 3 closely related serine/threonine-protein kinases (AKT1, AKT2 and AKT3) called the AKT kinase, and which regulate many processes including metabolism, proliferation, cell survival, growth and angiogenesis
  • This is mediated through serine and/or threonine phosphorylation of a range of downstream substrates
  • Over 100 substrate candidates have been reported so far, but for most of them, no isoform specificity has been reported
  • AKT is responsible of the regulation of glucose uptake by mediating insulin-induced translocation of the SLC2A4/GLUT4 glucose transporter to the cell surface
  • Phosphorylation of PTPN1 at 'Ser-50' negatively modulates its phosphatase activity preventing dephosphorylation of the insulin receptor and the attenuation of insulin signaling
  • Phosphorylation of TBC1D4 triggers the binding of this effector to inhibitory 14-3-3 proteins, which is required for insulin-stimulated glucose transport
  • AKT regulates also the storage of glucose in the form of glycogen by phosphorylating GSK3A at 'Ser-21' and GSK3B at 'Ser-9', resulting in inhibition of its kinase activity.

Compare Similar Items

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Img

Thermo Scientific

PIMA542793

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Antigen:
AKT1/AKT2

Classification:
Recombinant Monoclonal

Concentration:
0.8 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P31749, P31750, P31751, P47196, P47197, Q60823

Gene Symbols:
AKT1, AKT2

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 381-480 of human AKT1/2 (P31749).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
1G0K5

Conjugate:
Unconjugated

Gene:
AKT2

Gene Alias:
AKT; AKT serine/threonine kinase 1; AKT serine/threonine kinase 2; AKT1; AKT1m; AKT2; CWS6; HIHGHH; murine thymoma viral (v-akt) homolog-2; PKB; PKB alpha; PKB beta; PKB-ALPHA; PKBB; PKBBETA; PRKBA; PRKBB; Protein kinase Akt-2; Protein kinase B; Protein kinase B alpha; protein kinase B beta; Proto-oncogene c-Akt; putative v-akt murine thymoma viral oncoprotein 2; RAC; rac protein kinase alpha; rac protein kinase beta; RAC-ALPHA; RAC-alpha serine/threonine-protein kinase; RAC-BETA; RAC-beta serine/threonine-protein kinase; RAC-PK-alpha; RAC-PK-beta; serine-threonine protein kinase; v-akt murine thymoma viral oncogene homolog 1; v-akt murine thymoma viral oncogene homolog 2; v-akt murine thymoma viral oncogene-like protein 1

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11651, 11652, 207, 208, 24185, 25233

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542795

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Antigen:
Vinculin

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.05% ProClin 300; pH 7.3

Gene Accession No.:
P18206, P85972, Q64727

Gene Symbols:
VCL

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human Vinculin (NP_0547061)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot

Clone:
9I3Y8

Conjugate:
Unconjugated

Gene:
VCL

Gene Alias:
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22330, 305679, 7414

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542796

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Antigen:
GluR2/GluR3

Classification:
Recombinant Monoclonal

Concentration:
1.15 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P19491, P19492, P23819, Q9Z2W9

Gene Symbols:
Gria2, Gria3

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 784-883 of human GluR2+GluR3 (P42262).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
4K7G5

Conjugate:
Unconjugated

Gene:
Gria2

Gene Alias:
2900064I19Rik; AMPA selective glutamate receptor; AMPA-selective glutamate receptor 2; AMPA-selective glutamate receptor 3; dJ1171F9.1; GluA2; GluA3; GLUR2; GluR-2; GLUR3; GluR-3; Gluralpha3; GLURB; gluR-B; GLURC; GLUR-C; GluR-K2; GluR-K3; glutamate ionotropic receptor AMPA type subunit 2; glutamate ionotropic receptor AMPA type subunit 3; glutamate receptor; glutamate receptor 2; Glutamate receptor 3; glutamate receptor B; glutamate receptor B flip isoform; glutamate receptor C; glutamate receptor channel alpha3 subunit; glutamate receptor ionotropic, AMPA 2; Glutamate receptor ionotropic, AMPA 3; glutamate receptor subunit 3; glutamate receptor, ionotrophic, AMPA 3; glutamate receptor, ionotropic, AMPA 2; glutamate receptor, ionotropic, AMPA 3; glutamate receptor, ionotropic, AMPA2 (alpha 2); glutamate receptor, ionotropic, AMPA3 (alpha 3); GPRC1C; GRIA2; GRIA3; GRM3; HBGR2; Kiaa4184; MGR3; MRX94

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14800, 29627, 29628, 53623

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Img

Thermo Scientific

PIMA542797

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Antigen:
AHCY

Classification:
Recombinant Monoclonal

Concentration:
0.33 mg/mL

Formulation:
PBS with 0.05% BSA, 50% glycerol and 0.02% sodium azide; pH 7.3

Gene Accession No.:
P10760, P23526, P50247

Gene Symbols:
AHCY

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300-400 of human AHCY (P23526).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Immunoprecipitation, Western Blot

Clone:
4E9H10

Conjugate:
Unconjugated

Gene:
AHCY

Gene Alias:
AA987153; Acetylation; Adenosylhomocysteinase; adoHcyase; AHCY; AL024110; cb1079; CuBP; D150; dtp; ducttrip; hm:zeh1173; hm:zeh1364; Hydrolase; Liver copper-binding protein; NAD; Polymorphism; S-adenosylhomocysteine hydrolase; S-adenosyl-L-homocysteine hydrolase; SAHH; wu:fj67b02

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
191, 269378, 29443

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid