PIMA544584

IDH1 (R132H) Recombinant Rabbit Monoclonal Antibody (RM390), Biotin, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA544584-Each-of-1 In Stock ₹ 33,625.08

PIMA544584 - Each of 1

₹ 33,625.08

In Stock

Quantity

1

Base Price: ₹ 33,625.08

GST (18%): ₹ 6,052.514

Total Price: ₹ 39,677.594

Antigen

IDH1 (R132H)

Classification

Recombinant Monoclonal

Concentration

100 μg/mL

Formulation

PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.

O75874

Gene Symbols

IDH1

Immunogen

A peptide corresponding to human (R132H mutant specific). The immunogen range is a synthetic peptide within amino acids 180-280 of human IDH1 with R132H mutant.

Quantity

50 μL

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Clone

RM390

Conjugate

Biotin

Gene

IDH1

Gene Alias

Cytosolic NADP-isocitrate dehydrogenase, epididymis luminal protein 216, epididymis secretory protein Li 26, HEL-216, HEL-S-26, IDCD, IDH, IDH1, IDH1-mutant, IDP, IDPC, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, isocitrate dehydrogenase [NADP] cytoplasmic, isocitrate dehydrogenase 1 (NADP+), isocitrate dehydrogenase 1 (NADP+), soluble, NADP(+)-specific ICDH, NADP-dependent isocitrate dehydrogenase, cytosolic, NADP-dependent isocitrate dehydrogenase, peroxisomal, oxalosuccinate decarboxylase, PICD

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

3417

Content And Storage

-20°C

Isotype

IgG

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Description

  • Isocitrate dehydrogenases such as IDH1 catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate
  • These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+)
  • Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic
  • Each NADP(+)-dependent isozyme is a homodimer
  • The protein encoded by this gene is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes
  • It contains the PTS-1 peroxisomal targeting signal sequence
  • The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid
  • The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production
  • This product is specific for IDH1 (mutant R132H).

Compare Similar Items

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Img

Thermo Scientific

PIMA544584

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Antigen:
IDH1 (R132H)

Classification:
Recombinant Monoclonal

Concentration:
100 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
O75874

Gene Symbols:
IDH1

Immunogen:
A peptide corresponding to human (R132H mutant specific). The immunogen range is a synthetic peptide within amino acids 180-280 of human IDH1 with R132H mutant.

Quantity:
50 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM390

Conjugate:
Biotin

Gene:
IDH1

Gene Alias:
Cytosolic NADP-isocitrate dehydrogenase, epididymis luminal protein 216, epididymis secretory protein Li 26, HEL-216, HEL-S-26, IDCD, IDH, IDH1, IDH1-mutant, IDP, IDPC, isocitrate dehydrogenase (NADP(+)) 1, cytosolic, isocitrate dehydrogenase [NADP] cytoplasmic, isocitrate dehydrogenase 1 (NADP+), isocitrate dehydrogenase 1 (NADP+), soluble, NADP(+)-specific ICDH, NADP-dependent isocitrate dehydrogenase, cytosolic, NADP-dependent isocitrate dehydrogenase, peroxisomal, oxalosuccinate decarboxylase, PICD

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3417

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544586

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Antigen:
Cytokeratin 8

Classification:
Recombinant Monoclonal

Concentration:
200 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P05787

Gene Symbols:
KRT8

Immunogen:
A peptide corresponding to the C-terminus of human Cytokeratin-8.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM266

Conjugate:
Unconjugated

Gene:
KRT8

Gene Alias:
AA960620, AL022697, AU019895, CARD2, cb186, CK8, CK-8, CYK8, CYKER, cytokeratin 8, cytokeratin 8 (370 AA), cytokeratin endo A, Cytokeratin-8, cytokeratin-A, DreK8, EndoA, etID33550.23, etID43142.23, etID43142.8, K2C8, K8, KERA, keratin 8, keratin 8, type II, keratin complex 2, basic, gene 8, keratin, type 2, gene 8, Keratin, type II cytoskeletal 8, keratin, type II cytoskeletal 8-like protein, keratin-8, KO, Krt-2.8, Krt2-8, krt8, LOW QUALITY PROTEIN: keratin, type II cytoskeletal 8, sb:cb186, type II cytokeratin A (no.8), type-II keratin Kb8, wu:fa20h05, wu:fa95h10, wu:fb96c06, zfk8, zf-K8

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3856

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544587

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Antigen:
Cytokeratin 18

Classification:
Recombinant Monoclonal

Concentration:
200 μg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
P05783

Gene Symbols:
KRT18

Immunogen:
A peptide corresponding to the N-terminus of human Cytokeratin-18.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM279

Conjugate:
Unconjugated

Gene:
KRT18

Gene Alias:
cb83, Cell proliferation-inducing gene 46 protein, CK 18, CK18, CK-18, CYK18, cytokeratin 18, cytokeratin endo B, cytokeratin type -1, DAPK-1, Cytokeratin18, cytokeratin-18, dapk1, dorsal aorta proneprin kinesin-1, DreK18, Endo B, I79_023185, K 18, K18, keratin 18, keratin 18, type I, keratin 18a, tandem duplicate 1, keratin complex 1, acidic, gene 18, keratin D, Keratin, type I cytoskeletal 18, Keratin18, keratin-18, Kerd, KRT 18, Krt1-18, KRT18, krt18 {ECO:0000250, krt18a.1, LOC100008885, PIG46, sb:cb83, type I cytoskeletal 18, UniProtKB:P05783}, wu:fa13f02, wu:fb36b04

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
3875

Content And Storage:
-20°C

Isotype:
IgG

Img

Thermo Scientific

PIMA544588

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Antigen:
SMAD4

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 1% BSA, 50% glycerol and 0.09% sodium azide

Gene Accession No.:
O70437, P97471, Q13485

Gene Symbols:
SMAD4

Immunogen:
A peptide corresponding to the C-terminus of human Smad4.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Clone:
RM277

Conjugate:
Unconjugated

Gene:
SMAD4

Gene Alias:
AW743858, D18Wsu70e, Deleted in Pancreatic Carcinoma 4 (DPC4), deleted in pancreatic carcinoma locus 4, deletion target in pancreatic carcinoma 4, Deletion target in pancreatic carcinoma 4 homolog, DPC4, hSMAD4, JIP, MAD (mothers against decapentaplegic Drosophila) homolog 4, MAD homolog 4, MAD homolog 4 (MADH4), Madh4, mothers against decapentaplegic homolog 4, Mothers against decapentaplegic homolog 4 (MADH4), mothers against decapentaplegic, Drosophila, homolog of, 4, mothers against DPP homolog 4, MYHRS, SMAD, SMAD 4, SMAD family member 4, SMAD, mothers against DPP homolog 4, SMAD4

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
17128, 4089, 50554

Content And Storage:
-20°C

Isotype:
IgG