PIMA547659
CD244 (2B4) Monoclonal Antibody (M053), Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547659-Each-of-1 | In Stock | ₹ 45,817.38 |
PIMA547659 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,817.38
GST (18%): ₹ 8,247.128
Total Price: ₹ 54,064.508
Antigen
CD244 (2B4)
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
Q9BZW8
Gene Symbols
CD244
Immunogen
Clone (M053) was generated from a recombinant protein that included the extracellular region of human CD244 protein.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
M053
Conjugate
Unconjugated
Gene
CD244
Gene Alias
NKR2B4; SLAMF4
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
51744
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
Related Products
Description
- Clone M053 mouse monoclonal antibody detects a 110 kDa* protein on SDS-PAGE Native or denatured immunoblots of human THP1 monocytes
- The antibody prefers the native CD244 protein, but also detects denatured CD244
- The antibody works for western blot, immunoprecipitation, immunocytochemistry, and ELISA capture
- CD244 (Natural killer (NK) cell receptor 2B4/SLAMF4) is an Ig superfamily signaling lymphocyte activation molecule (SLAM) receptor
- Like all SLAM family receptors, it has an extracellular segment with two immunoglobulin (Ig)-like domains, and a cytoplasmic domain containing four immunoreceptor tyrosine-based switch motifs
- CD244 does not act as a selfligand similar to other SLAM family receptors
- It binds CD48, a transmembrane receptor ubiquitously expressed on hematopoietic cells
- CD244 activity is controlled by the presence or absence of small cytoplasmic adapter proteins, SH2D1A/SAP and/or SH2D1B/EAT-2
- Downstream signaling involves predominantly VAV1, and, to a lesser degree, INPP5D/SHIP1 and CBL
- Activation of CD244 stimulates NK cell cytotoxicity, production of IFN-gamma and granule exocytosis
- CD244 is involved in the regulation of CD8+ T-cell proliferation, and inhibits inflammatory responses in dendritic cells (DCs)
- In cancers, CD244 shows increased expression in intratumoral DCs and myeloid suppressor cells, and anti-CD244 therapies may increase infiltrating T-cells and impair tumor growth.
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Antigen: CD244 (2B4)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q9BZW8
Gene Symbols: CD244
Immunogen: Clone (M053) was generated from a recombinant protein that included the extracellular region of human CD244 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M053
Conjugate: Unconjugated
Gene: CD244
Gene Alias: NKR2B4; SLAMF4
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 51744
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
CD244 (2B4)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q9BZW8
Gene Symbols:
CD244
Immunogen:
Clone (M053) was generated from a recombinant protein that included the extracellular region of human CD244 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M053
Conjugate:
Unconjugated
Gene:
CD244
Gene Alias:
NKR2B4; SLAMF4
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
51744
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: CD244 (2B4)
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q9BZW8
Gene Symbols: CD244
Immunogen: Clone (M085) was generated from a recombinant protein that included the extracellular region of human CD244 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M085
Conjugate: Unconjugated
Gene: CD244
Gene Alias: NKR2B4; SLAMF4
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 51744
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
CD244 (2B4)
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q9BZW8
Gene Symbols:
CD244
Immunogen:
Clone (M085) was generated from a recombinant protein that included the extracellular region of human CD244 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M085
Conjugate:
Unconjugated
Gene:
CD244
Gene Alias:
NKR2B4; SLAMF4
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
51744
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: CD47
Classification: Monoclonal
Concentration: 0.25 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q08722
Gene Symbols: CD47
Immunogen: Clone (M054) was generated from a recombinant protein that included the extracellular region of human CD47 protein.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M054
Conjugate: Unconjugated
Gene: CD47
Gene Alias: 9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 961
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
CD47
Classification:
Monoclonal
Concentration:
0.25 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q08722
Gene Symbols:
CD47
Immunogen:
Clone (M054) was generated from a recombinant protein that included the extracellular region of human CD47 protein.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M054
Conjugate:
Unconjugated
Gene:
CD47
Gene Alias:
9130415E20Rik; AA407862; AI848868; antigen identified by monoclonal antibody 1D8; antigenic surface determinant protein OA3; AW108519; B430305P08Rik; Cd47; CD47 antigen; CD47 antigen (Rh-related antigen, integrin-associated signal transducer); CD47 antigen/integrin-associated protein; CD47 glycoprotein; CD47 molecule; CD47/IAP; IAP; integrin associated protein; integrin-associated protein; integrin-associated signal transducer; Itgp; Leukocyte surface antigen CD47; MER6; OA3; Protein MER6; Rh-related antigen; sCD47; soluble CD 47; soluble CD47
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
961
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Cyclophilin B
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P23284
Gene Symbols: PPIB
Immunogen: Clone M019 was generated from a proprietary antigen related to cyclophilin B from the MCF7 breast cancer cell line.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M019
Conjugate: Unconjugated
Gene: PPIB
Gene Alias: AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 5479
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Cyclophilin B
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P23284
Gene Symbols:
PPIB
Immunogen:
Clone M019 was generated from a proprietary antigen related to cyclophilin B from the MCF7 breast cancer cell line.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M019
Conjugate:
Unconjugated
Gene:
PPIB
Gene Alias:
AA408962; AA553318; AI844835; Cphn2; Cphn-2; cyclophilin B; cyclophilin-like protein; Cyp B; CyP-20b; CYPB; CYP-S1; EC 5.2.1.8; epididymis secretory protein Li 39; HEL-S-39; OI9; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B; peptidylprolyl isomerase B (cyclophilin B); PPIase; PPIase B; Ppib; Rotamase; Rotamase B; S-cyclophilin; S-cyclophylin; SCYLP
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
5479
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1