PIMA547718
Dysadherin Monoclonal Antibody (M031), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA547718-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA547718 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
Dysadherin
Classification
Monoclonal
Concentration
Lot-Specific
Formulation
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.
Q96DB9
Gene Symbols
FXYD5
Immunogen
Clone (M031) was generated from a proprietary antigen related to the native human FXYD5 protein expressed in MDA-MB-231 breast cancer cell line.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone
M031
Conjugate
Unconjugated
Gene
FXYD5
Gene Alias
DYSAD; Dysadherin; EF-8; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; FXYD5; HSPC113; Ion channel homolog RIC; IWU1; IWU-1; KCT1; keratinocytes associated transmembrane protein 1; OIT2; oncoprotein induced transcript 2; oncoprotein-induced protein 2; PRO6241; RIC; UNQ2561/PRO6241
Host Species
Mouse
Purification Method
Protein G
Regulatory Status
RUO
Gene ID (Entrez)
53827
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG1
Description
- Clone M031 mouse monoclonal antibody detects a 35-55 kDa* band on SDS-PAGE immunoblots of human A431, A549, MeWo, MDA-MB-231 cell, as well as human breast, lung, and skin tissues
- The antibody works for western blot, immunoprecipitation, ELISA, and immunocytochemistry, as well as detects the FXYD5 protein on live cells
- This gene encodes a member of a family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 in variant and 6 highly conserved amino acids
- The approved human gene nomenclature for the family is FXYD-domain containing ion transport regulator
- Mouse FXYD5 has been termed RIC (Related to Ion Channel)
- FXYD2, also known as the gamma subunit of the Na,K-ATPase, regulates the properties of that enzyme
- FXYD1 (phospholemman), FXYD2 (gamma), FXYD3 (MAT-8), FXYD4 (CHIF), and FXYD5 (RIC) have been shown to induce channel activity in experimental expression systems
- Transmembrane topology has been established for two family members (FXYD1 and FXYD2), with the N-terminus extracellular and the C-terminus on the cytoplasmic side of the membrane
- This gene product, FXYD5, is a glycoprotein that functions in the up-regulation of chemokine production, and it is involved in the reduction of cell adhesion via its ability to down-regulate E-cadherin
- It also promotes metastasis, and has been linked to a variety of cancers
- Alternative splicing results in multiple transcript variants.
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Antigen: Dysadherin
Classification: Monoclonal
Concentration: Lot-Specific
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q96DB9
Gene Symbols: FXYD5
Immunogen: Clone (M031) was generated from a proprietary antigen related to the native human FXYD5 protein expressed in MDA-MB-231 breast cancer cell line.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Clone: M031
Conjugate: Unconjugated
Gene: FXYD5
Gene Alias: DYSAD; Dysadherin; EF-8; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; FXYD5; HSPC113; Ion channel homolog RIC; IWU1; IWU-1; KCT1; keratinocytes associated transmembrane protein 1; OIT2; oncoprotein induced transcript 2; oncoprotein-induced protein 2; PRO6241; RIC; UNQ2561/PRO6241
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 53827
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Dysadherin
Classification:
Monoclonal
Concentration:
Lot-Specific
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q96DB9
Gene Symbols:
FXYD5
Immunogen:
Clone (M031) was generated from a proprietary antigen related to the native human FXYD5 protein expressed in MDA-MB-231 breast cancer cell line.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Clone:
M031
Conjugate:
Unconjugated
Gene:
FXYD5
Gene Alias:
DYSAD; Dysadherin; EF-8; FXYD domain containing ion transport regulator 5; FXYD domain-containing ion transport regulator 5; FXYD5; HSPC113; Ion channel homolog RIC; IWU1; IWU-1; KCT1; keratinocytes associated transmembrane protein 1; OIT2; oncoprotein induced transcript 2; oncoprotein-induced protein 2; PRO6241; RIC; UNQ2561/PRO6241
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
53827
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Girdin
Classification: Monoclonal
Concentration: ∽0.125 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: Q3V6T2
Gene Symbols: CCDC88A
Immunogen: Clone (M012) was generated from a recombinant protein that included amino acid residues within the C-terminal region of human Girdin.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone: M012
Conjugate: Unconjugated
Gene: CCDC88A
Gene Alias: A430106J12Rik; AI848406; Akt phosphorylation enhancer; AKT-phosphorylation enhancer; Ape; C130096N06Rik; C330012F17Rik; Ccdc88a; coiled coil domain containing 88A; coiled-coil domain containing 88A; coiled-coil domain-containing protein 88A; D130005J21Rik; G alpha-interacting vesicle-associated protein; Galpha-interacting vesicle-associated protein; girders of actin filament; girders of actin filaments; girdin; GIV; Grdn; HkRP1; Hook-related protein 1; KIAA1212; RGD1306694
Host Species: Mouse
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 55704
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
Girdin
Classification:
Monoclonal
Concentration:
∽0.125 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
Q3V6T2
Gene Symbols:
CCDC88A
Immunogen:
Clone (M012) was generated from a recombinant protein that included amino acid residues within the C-terminal region of human Girdin.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot
Clone:
M012
Conjugate:
Unconjugated
Gene:
CCDC88A
Gene Alias:
A430106J12Rik; AI848406; Akt phosphorylation enhancer; AKT-phosphorylation enhancer; Ape; C130096N06Rik; C330012F17Rik; Ccdc88a; coiled coil domain containing 88A; coiled-coil domain containing 88A; coiled-coil domain-containing protein 88A; D130005J21Rik; G alpha-interacting vesicle-associated protein; Galpha-interacting vesicle-associated protein; girders of actin filament; girders of actin filaments; girdin; GIV; Grdn; HkRP1; Hook-related protein 1; KIAA1212; RGD1306694
Host Species:
Mouse
Purification Method:
Protein G
Regulatory Status:
RUO
Gene ID (Entrez):
55704
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: CD61 (Integrin beta 3)
Classification: Monoclonal
Concentration: 0.08 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: O54890, P05106
Gene Symbols: ITGB3
Immunogen: Clone M581 was generated from a recombinant protein containing amino acid residues in the extracellular region of human Integrin beta3. This sequence has high homology with rat and mouse Integrin beta3, and has low homology to other integrin family members.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: M581
Conjugate: Unconjugated
Gene: ITGB3
Gene Alias: antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 16416, 29302, 3690
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG1
Antigen:
CD61 (Integrin beta 3)
Classification:
Monoclonal
Concentration:
0.08 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
O54890, P05106
Gene Symbols:
ITGB3
Immunogen:
Clone M581 was generated from a recombinant protein containing amino acid residues in the extracellular region of human Integrin beta3. This sequence has high homology with rat and mouse Integrin beta3, and has low homology to other integrin family members.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
M581
Conjugate:
Unconjugated
Gene:
ITGB3
Gene Alias:
antigen CD61; BDPLT16; BDPLT2; beta3 integrin; CD61; EGK_08849; glycoprotein GPIIIa; glycoprotein IIIa; GP3A; GPIIIa; GT; INGRB3; integrin beta 3; integrin beta 3 (Cd61); integrin beta-3; integrin beta-3 subunit; integrin subunit beta 3; integrin, beta 3; integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61); ITGB3; platelet glycoprotein IIIa; platelet glycoprotein IIIa integrin subunit beta 3; platelet gpIIIa; platelet membrane glycoprotein IIIa
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
16416, 29302, 3690
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG1
Antigen: Laminin beta-2/gamma-1
Classification: Monoclonal
Concentration: ∽1.0 mg/mL
Formulation: PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.: P11047, P55268
Gene Symbols: LAMB2, LAMC1
Immunogen: Clone (M046) was generated from a recombinant human laminin 521 protein that includes a heterotrimer of three subunits laminin alpha5, laminin beta2, and laminin gamma1 subunits.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Clone: M046
Conjugate: Unconjugated
Gene: LAMB2
Gene Alias: AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma
Host Species: Mouse
Purification Method: Protein A
Regulatory Status: RUO
Gene ID (Entrez): 3913, 3915
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG2b
Antigen:
Laminin beta-2/gamma-1
Classification:
Monoclonal
Concentration:
∽1.0 mg/mL
Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide
Gene Accession No.:
P11047, P55268
Gene Symbols:
LAMB2, LAMC1
Immunogen:
Clone (M046) was generated from a recombinant human laminin 521 protein that includes a heterotrimer of three subunits laminin alpha5, laminin beta2, and laminin gamma1 subunits.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Clone:
M046
Conjugate:
Unconjugated
Gene:
LAMB2
Gene Alias:
AA408497; AW211941; B2e; basement membrane protein; Lama; Lamb2; Lamb-2; Lamc1; Laminin B1s chain; laminin B2 chain; laminin beta 2; laminin beta 2 chain; laminin chain B3; laminin chain beta 2; laminin gamma 1 chain; Laminin S; laminin subunit beta 2; laminin subunit beta-2; laminin subunit gamma 1; laminin subunit gamma-1; laminin, beta 2; laminin, beta 2 (laminin S); laminin, gamma 1; laminin, gamma 1 (formerly LAMB2); laminin-1 subunit gamma; Laminin-10 subunit gamma; laminin-11 subunit beta; Laminin-11 subunit gamma; laminin-14 subunit beta; Laminin-15 subunit beta; laminin-2 subunit gamma; Laminin-3 subunit beta; laminin-3 subunit gamma; Laminin-4 subunit beta; laminin-4 subunit gamma; Laminin-6 subunit gamma; laminin-7 subunit beta; Laminin-7 subunit gamma; laminin-8 subunit gamma; Laminin-9 subunit beta; laminin-9 subunit gamma; LAMS; NPHS5; npht; SLAM; S-LAM beta; S-LAM gamma; S-laminin subunit beta; S-laminin subunit gamma
Host Species:
Mouse
Purification Method:
Protein A
Regulatory Status:
RUO
Gene ID (Entrez):
3913, 3915
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG2b