PIMA548057

INSR alpha Recombinant Mouse Monoclonal Antibody (Fab 83-7), Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIMA548057-Each-of-1 In Stock ₹ 44,961.78

PIMA548057 - Each of 1

₹ 44,961.78

In Stock

Quantity

1

Base Price: ₹ 44,961.78

GST (18%): ₹ 8,093.12

Total Price: ₹ 53,054.90

Antigen

INSR alpha

Classification

Recombinant Monoclonal

Concentration

1 mg/mL

Formulation

PBS with 0.02% ProClin 300

Gene Accession No.

P06213

Gene Symbols

INSR

Immunogen

This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Quantity

200 μg

Primary or Secondary

Primary

Target Species

Human

Form

Liquid

Applications

In vitro Assay

Clone

Fab 83-7

Conjugate

Unconjugated

Gene

INSR

Gene Alias

4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species

Mouse

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3643

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype

IgG1 κ

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Description

  • Specificity: This antibody recognizes an epitope within the cysteine rich region (amino acids 140-301) of the extracellular domain of the human insulin receptor alpha
  • Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
  • The insulin receptor
  • Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
  • These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
  • Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
  • Both these signaling cascades are also important for the development of cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIMA548057

--


Antigen:
INSR alpha

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
In vitro Assay

Clone:
Fab 83-7

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Mouse

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 κ

Img

Thermo Scientific

PIMA548058

--


Antigen:
INSR alpha Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
INSR

Immunogen:
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
Immunocytochemistry, In vitro Assay

Clone:
Fab 83-7

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG κ

Img

Thermo Scientific

PIMA548059

--


Antigen:
Galiximab

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
__

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays

Clone:
IDEC-114 (Galiximab)

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
IDEC-114

Host Species:
Human

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG1 λ

Img

Thermo Scientific

PIMA548060

--


Antigen:
Galiximab Chimeric

Classification:
Recombinant Monoclonal

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% ProClin 300

Gene Accession No.:
P06213

Gene Symbols:
__

Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.

Quantity:
200 μg

Primary or Secondary:
Primary

Target Species:
Human

Form:
Liquid

Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation

Clone:
IDEC-114 (Galiximab)

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
IDEC-114

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3643

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Isotype:
IgG λ