PIMA548058
INSR alpha Chimeric Recombinant Rabbit Monoclonal Antibody (Fab 83-7), Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIMA548058-Each-of-1 | In Stock | ₹ 44,961.78 |
PIMA548058 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,961.78
GST (18%): ₹ 8,093.12
Total Price: ₹ 53,054.90
Antigen
INSR alpha Chimeric
Classification
Recombinant Monoclonal
Concentration
1 mg/mL
Formulation
PBS with 0.02% ProClin 300
Gene Accession No.
P06213
Gene Symbols
INSR
Immunogen
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.
Quantity
200 μg
Primary or Secondary
Primary
Target Species
Human
Form
Liquid
Applications
Immunocytochemistry, In vitro Assay
Clone
Fab 83-7
Conjugate
Unconjugated
Gene
INSR
Gene Alias
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species
Rabbit
Purification Method
Affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
3643
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype
IgG κ
Related Products
Description
- Specificity: This antibody recognizes an epitope within the cysteine rich region (amino acids 140-301) of the extracellular domain of the human insulin receptor alpha
- Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades
- The insulin receptor
- Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins
- These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor
- Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation
- Both these signaling cascades are also important for the development of cancer.
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Antigen: INSR alpha Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P06213
Gene Symbols: INSR
Immunogen: This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: Immunocytochemistry, In vitro Assay
Clone: Fab 83-7
Conjugate: Unconjugated
Gene: INSR
Gene Alias: 4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3643
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG κ
Antigen:
INSR alpha Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P06213
Gene Symbols:
INSR
Immunogen:
This antibody was raised by immunizing mice with IM-9 lymphocytes followed by purified insulin receptor.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
Immunocytochemistry, In vitro Assay
Clone:
Fab 83-7
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3643
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG κ
Antigen: Galiximab
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P06213
Gene Symbols: __
Immunogen: Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays
Clone: IDEC-114 (Galiximab)
Conjugate: Unconjugated
Gene: INSR
Gene Alias: IDEC-114
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3643
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 λ
Antigen:
Galiximab
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P06213
Gene Symbols:
__
Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunohistochemistry, Immunoprecipitation, Inhibition Assays
Clone:
IDEC-114 (Galiximab)
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
IDEC-114
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3643
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 λ
Antigen: Galiximab Chimeric
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: P06213
Gene Symbols: __
Immunogen: Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Clone: IDEC-114 (Galiximab)
Conjugate: Unconjugated
Gene: INSR
Gene Alias: IDEC-114
Host Species: Rabbit
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 3643
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG λ
Antigen:
Galiximab Chimeric
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
P06213
Gene Symbols:
__
Immunogen:
Galiximab was prepared by immunizing cynomolgus monkeys with recombinant CD80 antigen.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry, Immunoprecipitation
Clone:
IDEC-114 (Galiximab)
Conjugate:
Unconjugated
Gene:
INSR
Gene Alias:
IDEC-114
Host Species:
Rabbit
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
3643
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG λ
Antigen: Tocilizumab
Classification: Recombinant Monoclonal
Concentration: 1 mg/mL
Formulation: PBS with 0.02% ProClin 300
Gene Accession No.: __
Gene Symbols: __
Immunogen: This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity: 200 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Applications: ELISA, Inhibition Assays
Clone: rhPM-1 (Tocilizumab)
Conjugate: Unconjugated
Gene: __
Gene Alias: IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Host Species: Human
Purification Method: Affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): __
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype: IgG1 κ
Antigen:
Tocilizumab
Classification:
Recombinant Monoclonal
Concentration:
1 mg/mL
Formulation:
PBS with 0.02% ProClin 300
Gene Accession No.:
__
Gene Symbols:
__
Immunogen:
This antibody was prepared by CDR grafting of mouse AUK 12-20 antibody onto a human framework regions.
Quantity:
200 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid
Applications:
ELISA, Inhibition Assays
Clone:
rhPM-1 (Tocilizumab)
Conjugate:
Unconjugated
Gene:
__
Gene Alias:
IL-6R; Actemra; Atlizumab; MRA; R-1569; RHPM-1; RO-4877533
Host Species:
Human
Purification Method:
Affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
__
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Isotype:
IgG1 κ