PIPA5104938

Phospho-ADAM17 (Thr735) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5104938-Each-of-1 In Stock ₹ 44,362.86

PIPA5104938 - Each of 1

₹ 44,362.86

In Stock

Quantity

1

Base Price: ₹ 44,362.86

GST (18%): ₹ 7,985.315

Total Price: ₹ 52,348.175

Antigen

Phospho-ADAM17 (Thr735)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ADAM17

Gene Alias

a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11491, 57027, 6868

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P78536, Q9Z0F8, Q9Z1K9

Gene Symbols

ADAM17

Immunogen

A synthesized peptide derived from human ADAM17(Accession P78536), corresponding to amino acid residues around phosphorylated Thr735.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of ADAM 17 only when phosphorylated at Threonine 735
  • ADAM17 (disintegrin and metalloproteinase domain-containing protein 17) cleaves the membrane bound precusor of TNF-alpha to its mature soluble form
  • ADAM 17 is responsbile for the proteolytical release of soluble JAM3 from endothelial cells surface and the proteolytic release of several other cell-surface proteins, including p75 TNF-receptor, interleukin receptor type II, p55 TNF-receptor, transforming growth factor-alpha, L-selectin, growth hormone receptor, MUC1, and the amyloid precursor protein
  • It acts as an activator of the Notch pathway by mediating cleavage of Notch and generating the membrane-associated intermediate fragment called Notch extracellular truncation (NEXT)
  • Mutations in the gene can result in inflammatory skin and bowel disease, neonatal 1.

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Thermo Scientific

PIPA5104938

--


Antigen:
Phospho-ADAM17 (Thr735)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ADAM17

Gene Alias:
a disintegrin and metallopeptidase domain 17; a disintegrin and metalloprotease domain 17; a disintegrin and metalloproteinase; a disintegrin and metalloproteinase domain 17; a disintegrin and metalloproteinase domain 17 (tumor necrosis factor, alpha, converting enzyme); ADAM; ADAM 17; ADAM metallopeptidase domain 17; ADAM metallopeptidase domain 18; Adam17; ADAM18; ADAMs; CD156B; CD156b antigen; CSVP; Disintegrin and metalloproteinase domain-containing protein 17; metalloendopeptidases; NISBD; NISBD1; Snake venom-like protease; TACE; TNF-alpha convertase; TNF-alpha converting enzyme; TNF-alpha-converting enzyme; tumor necrosis factor, alpha, converting enzyme

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11491, 57027, 6868

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P78536, Q9Z0F8, Q9Z1K9

Gene Symbols:
ADAM17

Immunogen:
A synthesized peptide derived from human ADAM17(Accession P78536), corresponding to amino acid residues around phosphorylated Thr735.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5104942

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Antigen:
Phospho-Smad3 (Ser213)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smad3

Gene Alias:
AU022421; DKFZp586N0721; DKFZp686J10186; hMAD-3; hSMAD3; HSPC193; HsT17436; JV15-2; LDS1C; LDS3; MAD (mothers against decapentaplegic, Drosophila) homolog 3; MAD homolog 3; MAD homolog 3a; mad homolog JV15-2; mad protein homolog; MAD, mothers against decapentaplegic homolog 3; mad3; MAD-3; madh3; madh3a; madh3-A; MGC60396; mMad3; mothers against decapentaplegic homolog 3; mothers against decapentaplegic homolog 3a; mothers against DPP homolog 3; SMA- and MAD-related protein 3; SMAD; Smad 3; SMAD family member 3; SMAD family member 3 L homeolog; SMAD family member 3a; SMAD, mothers against DPP homolog 3; Smad3; smad3.L; smad3a; TGF beta response effector Smad3; TGF-beta response effector Smad3; transcription factor; transcription factor Smad3; wu:fa99e03; XELAEV_18018454mg; XenMLP; Xmad3; XSmad3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17127, 25631, 4088

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P84022, P84025, Q8BUN5

Gene Symbols:
Smad3

Immunogen:
A synthesized peptide derived from human SMAD3(Accession P84022), corresponding to amino acid residues around phosphorylated Ser213.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5104943

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Antigen:
Phospho-XIAP (Ser87)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
XIAP

Gene Alias:
1110015C02Rik; Aipa; Api3; apoptosis inhibitor protein 3; baculoviral IAP repeat-containing 4; baculoviral IAP repeat-containing protein 4; BIR4; Birc4; E3 ubiquitin-protein ligase XIAP; hIAP3; hIAP-3; HILP; IAP homolog A; IAP3; IAP-3; IAP-like protein; ILP; ILP1; ILP-1; Inhibitor of apoptosis protein 3; MIHA; riap3; RIAP-3; RING-type E3 ubiquitin transferase XIAP; RP1-315G1.5; XIAP; X-linked IAP; X-linked inhibitor of apoptosis; X-linked inhibitor of apoptosis protein; X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase; XLP2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11798, 331, 63879

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P98170, Q60989, Q9R0I6

Gene Symbols:
XIAP

Immunogen:
A synthesized peptide derived from human XIAP(Accession P98170), corresponding to amino acid residues around phosphorylated Ser87.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5104945

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Antigen:
Phospho-CDK5 (Tyr15)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CDK5

Gene Alias:
AW048668; Cdk5; CDK5 activator 1; CDK5-SV; CDKN5; Cell division protein kinase 5; CR6 protein kinase; Crk6; cyclin dependent kinase 5; cyclin-dependent kinase 5; cyclin-dependent-like kinase 5; LIS7; protein kinase CDK5 splicing; PSSALRE; Serine/threonine-protein kinase PSSALRE; tau protein kinase II catalytic subunit; TPKII catalytic subunit

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1020, 12568, 140908

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P49615, Q00535, Q03114

Gene Symbols:
CDK5

Immunogen:
A synthesized peptide derived from human CDK5(Accession Q00535), corresponding to amino acid residues around phosphorylated Tyr15.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG