PIPA5105087

Phospho-NEDD4 (Ser670) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105087-Each-of-1 In Stock ₹ 44,705.10

PIPA5105087 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-NEDD4 (Ser670)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEDD4

Gene Alias

AA959633; AL023035; AU019897; cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; NEDD4; NEDD-4; NEDD4 E3 ubiquitin protein ligase; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17999, 25489, 4734

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P46934, P46935, Q62940

Gene Symbols

NEDD4

Immunogen

A synthesized peptide derived from human NEDD4(Accession P46934), corresponding to amino acid residues around phosphorylated Ser670.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of NEDD4 only when phosphorylated at Ser670
  • The E3 ubiquitin-protein ligase NEDD4 is a Ubl conjugation pathway protein
  • It contains one HECT (E6AP-type E3 ubiquitin-protein ligase) domain and four WW domains
  • It is involved in the pathway leading to the degradation of VEGFR-2/KDFR, independently of its ubiquitin-ligase activity
  • It acts as a potential proto-oncogene that negatively regulates PTEN via ubiquitination, a paradigm analogous to that of Mdm2 and p53
  • It is also reported to be involved in the budding of many viruses and is the regulator of epithelial Na+ channels, which lead to arterial hypertension
  • NEDD4 protein is localized to the sarcolemmal region of muscle fibers
  • Increase in NEDD4 protein expression leads to unloaded and denervated muscles as well as a decrease in Notch1 expression
  • Hence it acts as down regulator of Notch-1 gene expression.

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Thermo Scientific

PIPA5105087

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Antigen:
Phospho-NEDD4 (Ser670)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEDD4

Gene Alias:
AA959633; AL023035; AU019897; cell proliferation-inducing gene 53 protein; E3 ubiquitin-protein ligase NEDD4; E430025J12Rik; HECT-type E3 ubiquitin transferase NEDD4; Kiaa0093; mKIAA0093; NEDD4; NEDD-4; NEDD4 E3 ubiquitin protein ligase; Nedd4-1; Nedd4a; Neural precursor cell expressed developmentally down-regulated protein 4; neural precursor cell expressed, developmentally down-regulated 4; neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4; neural precursor cell expressed, developmentally down-regulated gene 4a; neural precursor cell expressed, developmentally down-regulted gene 4; OTTHUMP00000217840; OTTHUMP00000217841; OTTHUMP00000217842; PIG53; receptor-potentiating factor 1; RPF1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17999, 25489, 4734

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P46934, P46935, Q62940

Gene Symbols:
NEDD4

Immunogen:
A synthesized peptide derived from human NEDD4(Accession P46934), corresponding to amino acid residues around phosphorylated Ser670.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105089

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Antigen:
Phospho-BRG1 (Ser610)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Smarca4

Gene Alias:
ATP-dependent helicase SMARCA4; b2b508.1Clo; b2b692Clo; BAF190; BAF190A; brahma protein-like 1; BRG1; brg-1; BRG1-associated factor 190A; BRM/SWI2-related gene 1; CSS4; FLJ39786; global transcription activator homologous sequence; homeotic gene regulator; HP1-BP72; hSNF2b; mitotic growth and transcription activator; MRD16; nuclear protein GRB1; protein brahma homolog 1; Protein BRG-1; RTPS2; SMARCA4; SNF2; Snf2b; SNF2beta; SNF2-beta; SNF2L4; SNF2LB; SNF2-like 4; sucrose nonfermenting-like 4; SW1/SNF; SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4; SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 4; SWI2; transcription activator BRG1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171379, 20586, 6597

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51532, Q3TKT4, Q8K1P7

Gene Symbols:
Smarca4

Immunogen:
A synthesized peptide derived from human SMARCA4(Accession P51532), corresponding to amino acid residues around phosphorylated Ser610.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105090

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Antigen:
Phospho-PABP (Tyr364)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PABPC1

Gene Alias:
Cytoplasmic poly(A)-binding protein 1-A; ePAB; hypothetical protein; PAB1; pabp; PABP 1; Pabp1; PABP-1; PABP-1A; PABP-1-A; PABP-A; Pabpc1; pabpc1.L; pabpc1.S; pabpc1a; pabpc1-a; pabpc1a protein; pabpc1-b; pabpc2; PabpI; PABPL1; poly A binding protein 1; poly A binding protein, cytoplasmic 1 a; poly(A) binding protein cytoplasmic 1; poly(A) binding protein, cytoplasmic 1; poly(A) binding protein, cytoplasmic 1 L homeolog; poly(A) binding protein, cytoplasmic 1 S homeolog; poly(A) binding protein, cytoplasmic 1a; poly(A) binding protein, cytoplasmic 2; poly(A)-binding protein 1; poly(A)-binding protein 1A; poly(A)-binding protein 1-A; polyadenylate-binding protein 1; Polyadenylate-binding protein 1A; Polyadenylate-binding protein 1-A; polyadenylate-binding protein 1A; poly(A) binding protein, cytoplasmic 1a; wu:fb16a02; wu:fi19b08; wu:fj12d09; wu:fj61f06; XELAEV_18033915mg; xPABP1-A; zgc:109879

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171350, 18458, 26986

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P11940, P29341, Q9EPH8

Gene Symbols:
PABPC1

Immunogen:
A synthesized peptide derived from human PABPC1(Accession P11940), corresponding to amino acid residues around phosphorylated Tyr364.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105092

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Antigen:
Phospho-KSR1 (Thr425)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KSR1

Gene Alias:
AW492498; B-KSR1; CAP kinase; D11Bhm183e; D11Bhm184e; hb; HB protein; kinase KSR1; Kinase suppressor of Ras 1; Ksr; KSR1; mKSR1; OTTHUMP00000162931; protein Hb; RSU2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16706, 360573, 8844

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q61097, Q8IVT5

Gene Symbols:
KSR1

Immunogen:
A synthesized peptide derived from human KSR1(Accession Q8IVT5), corresponding to amino acid residues around phosphorylated Thr425.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG