PIPA5105224

Phospho-NEDD4L (Ser342) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105224-Each-of-1 In Stock ₹ 44,705.10

PIPA5105224 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-NEDD4L (Ser342)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

NEDD4L

Gene Alias

1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23327, 291553, 83814

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

Q8CFI0, Q96PU5

Gene Symbols

NEDD4L

Immunogen

A synthesized peptide derived from human NEDD4L(Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser342.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5110138

--

Img

Thermo Scientific

PIPA5105087

--

Img

Thermo Scientific

PIPA5105078

--

Img

Thermo Scientific

PIPA5105321

--

Img

Thermo Scientific

PIPA5105353

--

Img

Thermo Scientific

PIPA5105074

--

Img

Thermo Scientific

PIPA5105235

--

Img

Thermo Scientific

PIPA5105016

--

Description

  • Antibody detects endogenous levels of NEDD4L only when phosphorylated at Ser342
  • NEDD4L is an E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates
  • NEDD4L inhibits TGF-beta signaling by triggering SMAD2 and TGFR1 ubiquitination and proteasome-dependent degradation
  • NEDD4L promotes ubiquitination and internalization of various plasma membrane channels such as ENaC, Nav1.2, Nav1.3, Nav1.5, Nav1.7, Nav1.8, Kv1.3, EAAT1 or CLC5
  • NEDD4L also promotes ubiquitination and degradation of SGK.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105224

--


Antigen:
Phospho-NEDD4L (Ser342)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NEDD4L

Gene Alias:
1300012C07Rik; E3 ubiquitin-protein ligase NEDD4-like; FLJ33870; HECT-type E3 ubiquitin transferase NED4L; hNEDD4-2; KIAA0439; NEDD4; NEDD4 like E3 ubiquitin protein ligase; NEDD4.2; Nedd4-2; nedd4b; NEDD4L; NEDL3; neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase; neural precursor cell expressed, developmentally down-regulated gene 4b; neural precursor cell expressed, developmentally down-regulated gene 4-like; RSP5; ubiquitin-protein ligase Nedd4-2; ubiquitin-protein ligase Rsp5; Unknown (protein for IMAGE:7986262)

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23327, 291553, 83814

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8CFI0, Q96PU5

Gene Symbols:
NEDD4L

Immunogen:
A synthesized peptide derived from human NEDD4L(Accession Q96PU5), corresponding to amino acid residues around phosphorylated Ser342.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105225

--


Antigen:
Phospho-CAMKK2 (Ser511)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CAMKK2

Gene Alias:
6330570N16Rik; AW061083; Ca+/Calmodulin-dependent protein kinase kinase beta (CaM-kinase kinase beta); calcium/calmodulin dependent protein kinase kinase 2; calcium/calmodulin-dependent protein kinase 2 beta; calcium/calmodulin-dependent protein kinase beta; calcium/calmodulin-dependent protein kinase kinase 2; calcium/calmodulin-dependent protein kinase kinase 2, beta; calcium/calmodulin-dependent protein kinase kinase beta; caM-kinase kinase 2; CaM-kinase kinase beta; CAMKK; caMKK 2; caM-KK 2; caMKK beta; CaM-KK beta; CAMKK beta protein; CAMKK2; CAMKKB; KIAA0787; MGC15254; mKIAA0787

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10645, 207565, 83506

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88831, Q8C078, Q96RR4

Gene Symbols:
CAMKK2

Immunogen:
A synthesized peptide derived from human CAMKK2(Accession Q96RR4), corresponding to amino acid residues around phosphorylated Ser511.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105226

--


Antigen:
Phospho-MNK1 (Thr250, Thr255)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MKNK1

Gene Alias:
2410048M24Rik; MAP kinase interacting serine/threonine kinase 1; MAP kinase signal-integrating kinase 1; MAP kinase-interacting serine/threonine kinase 1; MAP kinase-interacting serine/threonine-protein kinase 1; MAPK signal-integrating kinase 1; MKNK1; Mnk1; OTTHUMP00000009675; OTTHUMP00000009676

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17346, 8569

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O08605, Q9BUB5

Gene Symbols:
MKNK1

Immunogen:
A synthesized peptide derived from human MKNK1(Accession Q9BUB5), corresponding to amino acid residues around phosphorylated Thr250.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105228

--


Antigen:
Phospho-CARD11 (Ser652)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CARD11

Gene Alias:
0610008L17Rik; 2410011D02Rik; bcl10-interacting maguk protein 3; BENTA; BIMP3; Card11; CARD-containing MAGUK protein 1; Carma 1; CARMA1; caspase recruitment domain family member 11; caspase recruitment domain family, member 11; caspase recruitment domain-containing protein 11; IMD11; LOC100363332; MGC133069; PPBL

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100363332, 108723, 84433

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8CIS0, Q9BXL7

Gene Symbols:
CARD11

Immunogen:
A synthesized peptide derived from human CARD11(Accession Q9BXL7), corresponding to amino acid residues around phosphorylated Ser652.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG