PIPA5105184

Phospho-IRAK1 (Thr387) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105184-Each-of-1 In Stock ₹ 43,592.82

PIPA5105184 - Each of 1

₹ 43,592.82

In Stock

Quantity

1

Base Price: ₹ 43,592.82

GST (18%): ₹ 7,846.708

Total Price: ₹ 51,439.528

Antigen

Phospho-IRAK1 (Thr387)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Irak1

Gene Alias

AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

16179, 363520, 3654

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P51617, Q62406

Gene Symbols

Irak1

Immunogen

A synthesized peptide derived from human IRAK1(Accession P51617), corresponding to amino acid residues around phosphorylated Thr387.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of IRAK1 only when phosphorylated at Thr387
  • IL-1 receptor associated kinases (IRAKs) are serine/threonine kinases involved in signaling via Toll/IL-1 pathways
  • It is rapidly recruited by MYD88 to the receptor-signaling complex upon TLR activation
  • IRAK's association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation
  • Alternatively, IRAK1 can phosphorylate TIRAP to promote its ubiquitination and subsequent degradation
  • IRAK1 also phosphorylates the interferon regulatory factor 7 (IRF7) to induce its activation and translocation to the nucleus
  • This results in the transcriptional activiation of type I IFN genes, which drive the cell in an antiviral state.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105184

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Antigen:
Phospho-IRAK1 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Irak1

Gene Alias:
AA408924; Il1rak; interleukin 1 receptor associated kinase 1; interleukin-1 receptor-associated kinase 1; interleukin-1 receptor-associated kinase-1; IRAK; Irak1; IRAK-1; IRAK1-S; mPLK; pelle; Pelle homolog; pelle-like protein kinase; Plpk; RGD1563841

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 363520, 3654

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51617, Q62406

Gene Symbols:
Irak1

Immunogen:
A synthesized peptide derived from human IRAK1(Accession P51617), corresponding to amino acid residues around phosphorylated Thr387.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105185

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Antigen:
Phospho-ETK (Tyr40)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BMX

Gene Alias:
BMX; BMX non-receptor tyrosine kinase; bone marrow tyrosine kinase gene in chromosome X protein; Bone marrow tyrosine kinase gene in chromosome X protein homolog; BTK-like on X chromosome; cytoplasmic tyrosine-protein kinase BMX; epa3; Epithelial and endothelial tyrosine kinase; ETK; Etk/Bmx; Etk/Bmx cytosolic tyrosine kinase; NTK38; NTK38 tyrosine kinase; PSCTK2; PSCTK3; RGD1565643; Tyro8; TYRO8 protein tyrosine kinase 8

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12169, 660

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51813, P97504

Gene Symbols:
BMX

Immunogen:
A synthesized peptide derived from human BMX(Accession P51813), corresponding to amino acid residues around phosphorylated Tyr40.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105186

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Antigen:
Phospho-KIF11 (Thr926)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KIF11

Gene Alias:
Eg5; HKSP; KIF11; Kif8; Kifl1; Kines; kinesin 11; kinesin family member 11; kinesin-like 1; kinesin-like protein 1; Kinesin-like protein KIF11; kinesin-like spindle protein HKSP; Kinesin-related motor protein Eg5; Knsl1; MCLMR; Thyroid receptor-interacting protein 5; TR-interacting protein 5; TRIP5; TRIP-5

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16551, 171304, 3832

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P52732, Q6P9P6

Gene Symbols:
KIF11

Immunogen:
A synthesized peptide derived from human KIF11(Accession P52732), corresponding to amino acid residues around phosphorylated Thr926.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA5105190

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Antigen:
Phospho-FOXL2 (Ser238)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXL2

Gene Alias:
AU045128; Blepharophimosis; BPES; BPES1; epicanthus inversus; forkhead box L2; forkhead box protein L2; forkhead transcription factor; forkhead transcription factor FOXL2; forkhead transcription factor L2; Foxl2; LUSTR2; MGC14393; Pfrk; P-Frk; PINTO; pituitary forkhead factor; POF3; putative transcription factor foxl2

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
26927, 668

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O88470, P58012

Gene Symbols:
FOXL2

Immunogen:
A synthesized peptide derived from human FOXL2(Accession P58012), corresponding to amino acid residues around phosphorylated Ser238.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG