PIPA5105243

Phospho-RPH3A (Ser424) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5105243-Each-of-1 In Stock ₹ 44,705.10

PIPA5105243 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-RPH3A (Ser424)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

RPH3A

Gene Alias

2900002P20Rik; AU022689; AW108370; Exophilin 1; Exophilin1; Exophilin-1; KIAA0985; rabphilin 3A; rabphilin 3A homolog; rabphilin-3A; RPH3A

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

171039, 19894, 22895

Content And Storage

-20°C

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P47708, P47709, Q9Y2J0

Gene Symbols

RPH3A

Immunogen

A synthesized peptide derived from human RPH3A(Accession Q9Y2J0), corresponding to amino acid residues around phosphorylated Ser424.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Rabphilin 3A only when phosphorylated at Ser424
  • The carboxy-terminal of rabphilin-3A consists of two C2 domains, A and B, and the amino-terminal (residues 45-170) contains a cysteine-rich rich region with two zinc finger motifs
  • Rabphilin-3A belongs to a family of other carboxyterminal type (C-type) tandem C2 proteins, which includes synaptotagmins and Doc2
  • Rabphilin is expressed in neuroendocrine cells and co-localizes with Rab3A on synaptic vesicles and chromaffin granules
  • Rabphilin-3A binds Rab3a/GTP/Mg+ within amino-terminal residues 45 and 170
  • Rabphilin-3A binds calcium ions and phosphatidylinositol 4,5-bisphophate containing lipid vesicles within its C2 domains
  • Rabphilin-3A is a positive regulator of calcium dependent exocytosis, while Rab3a is a negative regulator of exocytosis
  • Although rabphilin-3A associates with Rab3a, they seem to influence exocytosis independently of each other
  • Rabphilin-3A effects are likely mediated through interactions with an unknown factor that recognizes the Rab3 binding domain.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5105243

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Antigen:
Phospho-RPH3A (Ser424)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RPH3A

Gene Alias:
2900002P20Rik; AU022689; AW108370; Exophilin 1; Exophilin1; Exophilin-1; KIAA0985; rabphilin 3A; rabphilin 3A homolog; rabphilin-3A; RPH3A

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
171039, 19894, 22895

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P47708, P47709, Q9Y2J0

Gene Symbols:
RPH3A

Immunogen:
A synthesized peptide derived from human RPH3A(Accession Q9Y2J0), corresponding to amino acid residues around phosphorylated Ser424.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105245

--


Antigen:
Phospho-ATF6 (Thr166)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ATF6

Gene Alias:
9130025P16Rik; 9630036G24; AA617266; AA789574; ACHM7; activating transcription factor 6; activating transcription factor 6 alpha; Activating transcription factor 6 beta; ATF 6; Atf6; ATF6 alpha; ATF6A; Atf6alpha; ATF6-alpha; Atf6b; ATF6beta; ATF6-beta; cAMP response element binding protein-related protein; cAMP response element-binding protein-related protein; cAMP responsive element binding protein-like 1; cAMP-dependent transcription factor ATF-6 alpha; cAMP-dependent transcription factor ATF-6 beta; cAMP-responsive element-binding protein-like 1; Crebl1; Creb-related protein; CREB-RP; Cyclic AMP-dependent transcription factor ATF-6 alpha; cyclic AMP-dependent transcription factor ATF-6 beta; DKFZp686P2194; ESTM49; FLJ21663; G13; Processed cyclic AMP-dependent transcription factor ATF-6 alpha; Processed cyclic AMP-dependent transcription factor ATF-6 beta; Protein G13

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12915, 1388, 226641, 22926, 304962, 406169

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
F6VAN0, G3V909, O35451, P18850, Q99941

Gene Symbols:
ATF6, ATF6B

Immunogen:
A synthesized peptide derived from human ATF6(Accession P18850), corresponding to amino acid residues around phosphorylated Thr166.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105246

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Antigen:
Phospho-RIP3 (Ser316)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RIPK3

Gene Alias:
2610528K09Rik; AW107945; Hcyp2; Homocysteine respondent protein HCYP2; mRIP3; receptor interacting protein 3; receptor interacting serine/threonine kinase 3; receptor-interacting protein 3; receptor-interacting serine/threonine-protein kinase 3; receptor-interacting serine-threonine kinase 3; Rip3; RIP-3; Ripk3; RIP-like protein kinase 3

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11035

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q9Y572

Gene Symbols:
RIPK3

Immunogen:
A synthesized peptide derived from human RIPK3(Accession Q9Y572), corresponding to amino acid residues around phosphorylated Ser316.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105247

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Antigen:
RyR3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RYR3

Gene Alias:
AI851294; Brain ryanodine receptor-calcium release channel; brain-type ryanodine receptor; C230090H21; calcium release channel; HBRR; Ryanodine receptor 3; RYR3; RYR-3; Type 3 ryanodine receptor

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20192, 6263

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
A2AGL3, Q15413

Gene Symbols:
RYR3

Immunogen:
A synthesized peptide derived from human RYR3(Accession Q15413), corresponding to amino acid residues A134-L184.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG