PIPA5105327
Phospho-SETD2 (Ser532) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105327-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5105327 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-SETD2 (Ser532)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Setd2
Gene Alias
4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
235626, 29072, 316013
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
E9Q5F9, Q9BYW2
Gene Symbols
Setd2
Immunogen
A synthesized peptide derived from human SETD2(Accession Q9BYW2), corresponding to amino acid residues around phosphorylated Ser532.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of SETD2 only when phosphorylated at Ser532
- Histone methyltransferase that specifically trimethylates 'Lys-36' of histone H3 (H3K36me3) using dimethylated 'Lys-36' (H3K36me2) as substrate
- Represents the main enzyme generating H3K36me3, a specific tag for epigenetic transcriptional activation
- Plays a role in chromatin structure modulation during elongation by coordinating recruitment of the FACT complex and by interacting with hyperphosphorylated POLR2A
- Acts as a key regulator of DNA mismatch repair in G1 and early S phase by generating H3K36me3, a mark required to recruit MSH6 subunit of the MutS alpha complex: early recruitment of the MutS alpha complex to chromatin to be replicated allows a quick identification of mismatch DNA to initiate the mismatch repair reaction
- H3K36me3 also plays an essential role in the maintenance of a heterochromatic state, by recruiting DNA methyltransferase DNMT3A
- H3K36me3 is also enhanced in intron-containing genes, suggesting that SETD2 recruitment is enhanced by splicing and that splicing is coupled to recruitment of elongating RNA polymerase
- Required during angiogenesis
- Recruited to the promoters of adenovirus 12 E1A gene in case of infection, possibly leading to regulate its expression.
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Antigen: Phospho-SETD2 (Ser532)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Setd2
Gene Alias: 4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 235626, 29072, 316013
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: E9Q5F9, Q9BYW2
Gene Symbols: Setd2
Immunogen: A synthesized peptide derived from human SETD2(Accession Q9BYW2), corresponding to amino acid residues around phosphorylated Ser532.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-SETD2 (Ser532)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Setd2
Gene Alias:
4921524K10Rik; BC031601; FLJ16420; FLJ22472; FLJ23184; FLJ45883; HBP231; HIF1; HIF-1; HIP-1; histone-lysine N-methyltransferase SETD2; hSET2; HSPC069; huntingtin interacting protein 1; huntingtin yeast partner B; Huntingtin-interacting protein 1; Huntingtin-interacting protein B; HYPB; Kiaa1732; Kif9; kinesin family member 9; KMT3A; LLS; lysine N-methyltransferase 3A; p231HBP; Protein-lysine N-methyltransferase SETD2; SET domain containing 2; SET domain containing 2, histone lysine methyltransferase; SET domain-containing protein 2; SET2; Setd2
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
235626, 29072, 316013
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
E9Q5F9, Q9BYW2
Gene Symbols:
Setd2
Immunogen:
A synthesized peptide derived from human SETD2(Accession Q9BYW2), corresponding to amino acid residues around phosphorylated Ser532.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-eIF4A1 (Tyr48)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EIF4A1
Gene Alias: ATP-dependent RNA helicase eIF4A-1; BM-010; DDX2A; Eif4; EIF4A; EIF-4A; Eif4a1; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1; initiation factor eIF-4A long form; QtsA-12280; unnamed protein product
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13681, 1973, 287436
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P60842, P60843
Gene Symbols: EIF4A1
Immunogen: A synthesized peptide derived from human EIF4A1(Accession P60842), corresponding to amino acid residues around phosphorylated Tyr48.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-eIF4A1 (Tyr48)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EIF4A1
Gene Alias:
ATP-dependent RNA helicase eIF4A-1; BM-010; DDX2A; Eif4; EIF4A; EIF-4A; Eif4a1; eIF-4A-I; eIF4A-I; eukaryotic initiation factor 4AI; Eukaryotic initiation factor 4A-I; eukaryotic translation initiation factor 4A, isoform 1; eukaryotic translation initiation factor 4A1; initiation factor eIF-4A long form; QtsA-12280; unnamed protein product
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13681, 1973, 287436
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P60842, P60843
Gene Symbols:
EIF4A1
Immunogen:
A synthesized peptide derived from human EIF4A1(Accession P60842), corresponding to amino acid residues around phosphorylated Tyr48.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-HFE2 (Ser48)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: HFE2
Gene Alias: 2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 148738, 310681, 69585
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q6ZVN8, Q7TQ32, Q8N7M5
Gene Symbols: HFE2
Immunogen: A synthesized peptide derived from human HFE2(Accession Q6ZVN8), corresponding to amino acid residues around phosphorylated Ser48.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-HFE2 (Ser48)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
HFE2
Gene Alias:
2310035L15Rik; 5230400G09Rik; AI414844; AI789733; DL M; DL-M; Fidgetin; haemojuvelin; HEMOCHROMATOSIS; hemochromatosis type 2 (juvenile); hemochromatosis type 2 (juvenile) (human homolog); hemochromatosis type 2 protein; Hemochromatosis type 2 protein homolog; hemojuvelin; Hemojuvelin BMP coreceptor; HFE 2; HFE2; HFE2A; HJV; JH; MGC23953; OTTHUMP00000059680; repulsive guidance molecule c; RGM C; RGM domain family member C; RGMC
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
148738, 310681, 69585
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q6ZVN8, Q7TQ32, Q8N7M5
Gene Symbols:
HFE2
Immunogen:
A synthesized peptide derived from human HFE2(Accession Q6ZVN8), corresponding to amino acid residues around phosphorylated Ser48.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-EED (Thr55)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: EED
Gene Alias: EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 13626, 293104, 8726
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: O75530, Q921E6
Gene Symbols: EED
Immunogen: A synthesized peptide derived from human EED(Accession O75530), corresponding to amino acid residues around phosphorylated Thr55.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-EED (Thr55)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
EED
Gene Alias:
EED; embryonic ectoderm development; Embryonic ectoderm development protein; ENSMUSG00000039373; HEED; l(7)5Rn; l7Rn5; lethal, Chr 7, Rinchik 5; lusk; Polycomb protein EED; WAIT1; WAIT-1; WD protein associating with integrin cytoplasmic tails 1
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
13626, 293104, 8726
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
O75530, Q921E6
Gene Symbols:
EED
Immunogen:
A synthesized peptide derived from human EED(Accession O75530), corresponding to amino acid residues around phosphorylated Thr55.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG