PIPA5105352

Phospho-Thioredoxin 1 (Thr100) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105352-Each-of-1 In Stock ₹ 39,999.30

PIPA5105352 - Each of 1

₹ 39,999.30

In Stock

Quantity

1

Base Price: ₹ 39,999.30

GST (18%): ₹ 7,199.874

Total Price: ₹ 47,199.174

Antigen

Phospho-Thioredoxin 1 (Thr100)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TXN

Gene Alias

ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

116484, 22166, 7295

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P10599, P10639, P11232

Gene Symbols

TXN, Txn1

Immunogen

A synthesized peptide derived from human TXN(Accession P10599), corresponding to amino acid residues around phosphorylated Thr100.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of TXN only when phosphorylated at Thr100
  • Thioredoxins (Trx) are small, multi-functional proteins with oxidoreductase activity and are ubiquitous in essentially all living cells
  • Trx contains a redox-active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site
  • The two cysteine residues in the conserved active centers can be oxidized to form intramolecular disulfide bonds
  • Reduction of the active site disulfide in oxidized Trx is catalyzed by Trx reductase with NADPH as the electron donor
  • The reduced Trx is a hydrogen donor for ribonucleotide reductase, the essential enzyme for DNA synthesis, and a potent general protein disulfide reductase with numerous functions in growth and redox regulations
  • Specific protein disulfide targets for reduction by Trx include protein disulfide-isomerase (PDI) and a number of transcription factors such as p53, NF-kB and AP-1 (T1-151)
  • Trx is also capable of removing H2O2, particularly when it is coupled with either methionine sulfoxide reductase or several isoforms of peroxiredoxins.

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Img

Thermo Scientific

PIPA5105352

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Antigen:
Phospho-Thioredoxin 1 (Thr100)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TXN

Gene Alias:
ADF; ATL-derived factor; AW550880; DKFZp686B1993; MGC61975; RP11-427L11.1; SASP; surface-associated sulphydryl protein; testicular tissue protein Li 199; thioredoxin; thioredoxin 1; thioredoxin delta 3; TRDX; TRX; TRX1; Txn; TXN delta 3; Txn1

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116484, 22166, 7295

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P10599, P10639, P11232

Gene Symbols:
TXN, Txn1

Immunogen:
A synthesized peptide derived from human TXN(Accession P10599), corresponding to amino acid residues around phosphorylated Thr100.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105353

--


Antigen:
Phospho-Caspase 2 Precursor (Ser340)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CASP2

Gene Alias:
CASP2; CASP-2; caspase 2; caspase 2 apoptosis-related cysteine peptidase; caspase-2; Caspase-2 subunit p12; Caspase-2 subunit p13; Caspase-2 subunit p18; Ich1; ICH-1; ICH-1 protease; ICH-1L; ICH-1L/1S; Nedd2; NEDD-2; Neural precursor cell expressed developmentally down-regulated protein 2; PPP1R57; Protease ICH-1; protein phosphatase 1, regulatory subunit 57

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12366, 64314, 835

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P29594, P42575, P55215

Gene Symbols:
CASP2

Immunogen:
A synthesized peptide derived from human CASP2(Accession P42575), corresponding to amino acid residues around phosphorylated Ser340.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105355

--


Antigen:
Phospho-SP7 (Thr319)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
SP7

Gene Alias:
6430578P22Rik; C22; MGC126598; OI11; OI12; osterix; OSX; Sp7; Sp7 transcription factor; Sp7 transcription factor 7; trans-acting transcription factor 7; transcription factor Sp7; Zinc finger protein osterix

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121340, 170574, 300260

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q8TDD2, Q8VI67

Gene Symbols:
SP7

Immunogen:
A synthesized peptide derived from human SP7(Accession Q8TDD2), corresponding to amino acid residues around phosphorylated Thr319.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105356

--


Antigen:
Phospho-PINK1 (Ser228)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PINK1

Gene Alias:
1190006F07Rik; AU042772; AW557854; BRPK; FLJ27236; mFLJ00387; PARK6; PINK 1; Pink1; PINK-1; protein kinase BRPK; PTEN induced putative kinase 1; PTEN-induced putative kinase protein 1; Serine/threonine-protein kinase PINK1, mitochondrial

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
298575, 65018, 68943

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
B5DFG1, Q99MQ3, Q9BXM7

Gene Symbols:
PINK1

Immunogen:
A synthesized peptide derived from human PINK1(Accession Q9BXM7), corresponding to amino acid residues around phosphorylated Ser228.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG