PIPA5105648
Phospho-IRF3 (Ser14) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5105648-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA5105648 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-IRF3 (Ser14)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
IRF3
Gene Alias
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species
Rabbit
Purification Method
sequential chromatography
Regulatory Status
RUO
Gene ID (Entrez)
292892, 3661, 54131
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P70671, Q14653
Gene Symbols
IRF3
Immunogen
A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser14.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Antibody detects endogenous levels of IRF3 only when phosphorylated at Ser14
- IFR3 (interferon regulatory factor 3) is a key transcriptional regulator of type I interferon (IFN)-dependent immune responses
- It plays a critical role in the innate immune response against DNA and RNA viruses
- IFR3 regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters
- It acts as a more potent activator of the IFN-beta gene than the IFN-alpha gene and plays a critical role in both the early and late phases of the IFNA/B gene induction
- IFR3 is found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA, or toll-like receptor signaling
- It is phosphorylated by IKBKE and TBK1 kinases
- This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes
- Mutations in the gene can result in encephalopathy, acute, infection-induced, herpes-specific 7.
Compare Similar Items
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Antigen: Phospho-IRF3 (Ser14)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IRF3
Gene Alias: C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 292892, 3661, 54131
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P70671, Q14653
Gene Symbols: IRF3
Immunogen: A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser14.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-IRF3 (Ser14)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IRF3
Gene Alias:
C920001K05Rik; IIAE7; Interferon regulatory factor 3; IRF3; IRF-3; IRF3 (phospho S386); IRF3 (pS386); IRF3 (pSer386); IRF3 phospho; IRF3 phospho S386; IRF3 phospho Ser386; phospho IRF3
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
292892, 3661, 54131
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P70671, Q14653
Gene Symbols:
IRF3
Immunogen:
A synthesized peptide derived from human IRF3(Accession Q14653), corresponding to amino acid residues around phosphorylated Ser14.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NFATC4 (Ser289)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Nfatc4
Gene Alias: 3110041H08Rik; AW107667; AW546455; Nfat3; NF-AT3; Nfatc4; NF-ATc4; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4; nuclear factor of activated T-cells 4; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription complex subunit NF-ATc4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 305897, 4776, 73181
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q14934, Q8K120
Gene Symbols: Nfatc4
Immunogen: A synthesized peptide derived from human NFATC4(Accession Q14934), corresponding to amino acid residues around phosphorylated Ser289.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NFATC4 (Ser289)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Nfatc4
Gene Alias:
3110041H08Rik; AW107667; AW546455; Nfat3; NF-AT3; Nfatc4; NF-ATc4; nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4; nuclear factor of activated T-cells 4; nuclear factor of activated T-cells, cytoplasmic 4; nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 4; T-cell transcription factor NFAT3; transcription complex subunit NF-ATc4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
305897, 4776, 73181
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q14934, Q8K120
Gene Symbols:
Nfatc4
Immunogen:
A synthesized peptide derived from human NFATC4(Accession Q14934), corresponding to amino acid residues around phosphorylated Ser289.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NuMA (Ser1225)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NUMA1
Gene Alias: 6720401E04Rik; AA764025; AL022610; AU014979; centrophilin stabilizes mitotic spindle in mitotic cells; NMP22; NMP-22; Nuclear matrix protein-22; Nuclear mitotic apparatus protein; Nuclear mitotic apparatus protein 1; NUMA; NuMA protein; Numa1; SP-H antigen; structural nuclear protein
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 101706, 308870, 4926
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: E9Q7G0, Q14980
Gene Symbols: NUMA1
Immunogen: A synthesized peptide derived from human NUMA1(Accession Q14980), corresponding to amino acid residues around phosphorylated Ser1225.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NuMA (Ser1225)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NUMA1
Gene Alias:
6720401E04Rik; AA764025; AL022610; AU014979; centrophilin stabilizes mitotic spindle in mitotic cells; NMP22; NMP-22; Nuclear matrix protein-22; Nuclear mitotic apparatus protein; Nuclear mitotic apparatus protein 1; NUMA; NuMA protein; Numa1; SP-H antigen; structural nuclear protein
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
101706, 308870, 4926
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
E9Q7G0, Q14980
Gene Symbols:
NUMA1
Immunogen:
A synthesized peptide derived from human NUMA1(Accession Q14980), corresponding to amino acid residues around phosphorylated Ser1225.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-NCF4 (Tyr243)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ncf4
Gene Alias: AI451400; CGD3; CTA-833B7.1; MGC3810; NCF; Ncf4; NCF-4; Neutrophil cytosol factor 4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4, 40kDa; neutrophil NADPH oxidase factor 4; OTTHUMP00000028736; OTTHUMP00000043756; P40PHOX; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4
Host Species: Rabbit
Purification Method: sequential chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17972, 4689
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P97369, Q15080
Gene Symbols: Ncf4
Immunogen: A synthesized peptide derived from human NCF4(Accession Q15080), corresponding to amino acid residues around phosphorylated Tyr243.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-NCF4 (Tyr243)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ncf4
Gene Alias:
AI451400; CGD3; CTA-833B7.1; MGC3810; NCF; Ncf4; NCF-4; Neutrophil cytosol factor 4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4, 40kDa; neutrophil NADPH oxidase factor 4; OTTHUMP00000028736; OTTHUMP00000043756; P40PHOX; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4
Host Species:
Rabbit
Purification Method:
sequential chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
17972, 4689
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P97369, Q15080
Gene Symbols:
Ncf4
Immunogen:
A synthesized peptide derived from human NCF4(Accession Q15080), corresponding to amino acid residues around phosphorylated Tyr243.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG