PIPA5105653

Phospho-NCF4 (Tyr243) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5105653-Each-of-1 In Stock ₹ 44,705.10

PIPA5105653 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-NCF4 (Tyr243)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ncf4

Gene Alias

AI451400; CGD3; CTA-833B7.1; MGC3810; NCF; Ncf4; NCF-4; Neutrophil cytosol factor 4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4, 40kDa; neutrophil NADPH oxidase factor 4; OTTHUMP00000028736; OTTHUMP00000043756; P40PHOX; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

17972, 4689

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P97369, Q15080

Gene Symbols

Ncf4

Immunogen

A synthesized peptide derived from human NCF4(Accession Q15080), corresponding to amino acid residues around phosphorylated Tyr243.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of p40 phox only when phosphorylated at Tyr243
  • The protein encoded by this gene is a cytosolic regulatory component of the superoxide-producing phagocyte NADPH-oxidase, a multicomponent enzyme system important for host defense
  • This protein is preferentially expressed in cells of myeloid lineage
  • It interacts primarily with neutrophil cytosolic factor 2 (NCF2/p67-phox) to form a complex with neutrophil cytosolic factor 1 (NCF1/p47-phox), which further interacts with the small G protein RAC1 and translocates to the membrane upon cell stimulation
  • This complex then activates flavocytochrome b, the membrane-integrated catalytic core of the enzyme system
  • The PX domain of this protein can bind phospholipid products of the PI(3) kinase, which suggests its role in PI(3) kinase-mediated signaling events
  • The phosphorylation of this protein was found to negatively regulate the enzyme activity
  • Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Compare Similar Items

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Img

Thermo Scientific

PIPA5105653

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Antigen:
Phospho-NCF4 (Tyr243)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ncf4

Gene Alias:
AI451400; CGD3; CTA-833B7.1; MGC3810; NCF; Ncf4; NCF-4; Neutrophil cytosol factor 4; neutrophil cytosolic factor 4; neutrophil cytosolic factor 4, 40kDa; neutrophil NADPH oxidase factor 4; OTTHUMP00000028736; OTTHUMP00000043756; P40PHOX; p40-phox; SH3 and PX domain-containing protein 4; SH3PXD4

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
17972, 4689

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97369, Q15080

Gene Symbols:
Ncf4

Immunogen:
A synthesized peptide derived from human NCF4(Accession Q15080), corresponding to amino acid residues around phosphorylated Tyr243.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5105656

--


Antigen:
Phospho-PSD93 (Tyr348)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
DLG2

Gene Alias:
A330103J02Rik; B230218P12Rik; B330007M19Rik; channel-associated protein of synapse-110; channel-associated protein of synapses, 110kDa; Chapsyn-1; chapsyn-110; discs large 2; discs large homolog 2; discs large MAGUK scaffold protein 2; discs, large homolog 2; discs, large homolog 2 (Drosophila); discs, large homolog 2, chapsyn-110; disks large homolog 2; DLG2; Dlgh2; Gm1197; Postsynaptic density protein PSD-93; PPP1R58; protein phosphatase 1, regulatory subunit 58; PSD93; PSD-93; synaptic density protein PSD-93

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1740, 23859, 64053

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15700, Q63622, Q91XM9

Gene Symbols:
DLG2

Immunogen:
A synthesized peptide derived from human DLG2(Accession Q15700), corresponding to amino acid residues around phosphorylated Tyr348.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105657

--


Antigen:
Phospho-C/EBP epsilon (Ser181)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CEBPE

Gene Alias:
C EBP; c/EBP epsilon; C/EBPe; C/EBPepsilon; C/EBP-epsilon; C/EBP-related protein 1; C/EPBe; CCAAT/enhancer binding protein (C/EBP), epsilon; CCAAT/enhancer binding protein , epsilon; CCAAT/enhancer binding protein epsilon; CCAAT/enhancer-binding protein epsilon; CEBPE; Crp1; Gm294

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1053, 110794, 25410

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P56261, Q15744, Q6PZD9

Gene Symbols:
CEBPE

Immunogen:
A synthesized peptide derived from human CEBPE(Accession Q15744), corresponding to amino acid residues around phosphorylated Ser181.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5105659

--


Antigen:
Phospho-GRK1 (Ser21)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
GRK1

Gene Alias:
G protein-coupled receptor kinase 1; G protein-coupled receptpr kinase 1; GPRK1; G-protein coupled receptor kinase 1; G-protein receptor kinase 1; GRK 1a/b; GRK1; GRK1a; rhodopsin kinase; rhodopsin kinase GRK1; Rhok; RK

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
24013, 6011, 81760

Content And Storage:
-20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
Q15835, Q63651, Q9WVL4

Gene Symbols:
GRK1

Immunogen:
A synthesized peptide derived from human GRK1(Accession Q15835), corresponding to amino acid residues around phosphorylated Ser21.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG