PIPA5118685

Phospho-Claudin 4 (Tyr208) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118685-Each-of-1 In Stock ₹ 41,539.38

PIPA5118685 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-Claudin 4 (Tyr208)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Cldn4

Gene Alias

Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12740, 1364, 304407

Content And Storage

-20°C

Form

Liquid

Applications

Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

O14493, O35054

Gene Symbols

Cldn4

Immunogen

A synthesized peptide derived from human CLDN4(Accession O14493), corresponding to amino acid residues around phosphorylated Tyr208.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Claudin 4 only when phosphorylated at Tyr208
  • Claudin-4 belongs to the 20-member family of claudins, transmembrane cellular adhesion proteins localized at epithelial and endothelial tight junctions
  • Claudins demonstrate distinct, tissue-specific expression patterns, and are essential components of tight junction charge-specific channels that regulate paracellular ion flux
  • Claudin-4 is a component of tight junction strands and may play a role in internal organ development and function during pre- and postnatal life
  • The overexpression of Claudin-4 has been shown to decrease paracellular electrical conductance due to a selective decrease in Na+ permeability, with no significant decrease in Cl<sup>-</sup> permeability
  • In ovarian carcinoma cells, Claudin-3 and Claudin-4 exhibit upregulation at both mRNA and protein levels
  • Claudin-4 is also overexpressed in pancreatic cancer tissues and cell lines, and in other epithelial cancers
  • The Claudin-4 gene is deleted in Williams-Beuren syndrome, a neurodevelopmental disorder affecting multiple systems.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA5118685

--


Antigen:
Phospho-Claudin 4 (Tyr208)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cldn4

Gene Alias:
Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12740, 1364, 304407

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14493, O35054

Gene Symbols:
Cldn4

Immunogen:
A synthesized peptide derived from human CLDN4(Accession O14493), corresponding to amino acid residues around phosphorylated Tyr208.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118686

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Antigen:
Phospho-delta Catenin (Tyr257)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNND1

Gene Alias:
AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12388, 1500, 311163

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60716, P30999

Gene Symbols:
CTNND1

Immunogen:
A synthesized peptide derived from human CTNND1(Accession O60716), corresponding to amino acid residues around phosphorylated Tyr257.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118687

--


Antigen:
Phospho-delta Catenin (Tyr904)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
CTNND1

Gene Alias:
AA409437; AU019353; cadherin-associated Src substrate; Cadherin-associated Src substrate (CAS); CAS; Catenin (cadherin associated protein) delta 1; catenin (cadherin associated protein), delta 1; catenin (cadherin-associated protein), delta 1; catenin delta 1; catenin delta-1; catenin src; catenin, delta 1; Catns; CTNND; Ctnnd1; hypothetical protein; Kiaa0384; mKIAA0384; p120; p120 catenin; P120 CTN; P120 p120; P120 P120CTN; p120(CAS); p120(ctn); P120CAS; p120-catenin; P120CTN

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12388, 1500

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O60716, P30999

Gene Symbols:
CTNND1

Immunogen:
A synthesized peptide derived from human CTNND1(Accession O60716), corresponding to amino acid residues around phosphorylated Tyr904.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA5118690

--


Antigen:
Phospho-Cyclin B1 (Ser128)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 268697, 891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277

Gene Symbols:
Ccnb1

Immunogen:
A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser128.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG