PIPA5118690

Phospho-Cyclin B1 (Ser128) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118690-Each-of-1 In Stock ₹ 41,539.38

PIPA5118690 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-Cyclin B1 (Ser128)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ccnb1

Gene Alias

Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25203, 268697, 891

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P14635, P24860, P30277

Gene Symbols

Ccnb1

Immunogen

A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser128.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA5118691

--

Img

Thermo Scientific

PIPA5119057

--

Img

Thermo Scientific

PIPA5118726

--

Img

Thermo Scientific

PIPA5118547

--

Img

Thermo Scientific

PIPA5118685

--

Img

Thermo Scientific

PIPA5118636

--

Img

Thermo Scientific

PIPA5118772

--

Img

Thermo Scientific

PIPA5118723

--

Description

  • Antibody detects endogenous levels of Cyclin B1 only when phosphorylated at Ser128
  • Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs)
  • Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis
  • It is essential for the control of the cell cycle at the G2/M transition
  • Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)
  • Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase
  • Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis
  • Destruction of Cyclin B1 is required for cell cycle progression
  • Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5118690

--


Antigen:
Phospho-Cyclin B1 (Ser128)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 268697, 891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277

Gene Symbols:
Ccnb1

Immunogen:
A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser128.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118691

--


Antigen:
Phospho-Cyclin B1 (Ser133)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 268697, 891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277

Gene Symbols:
Ccnb1

Immunogen:
A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser133.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118692

--


Antigen:
Phospho-FOXO3A (Ser318)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXO3

Gene Alias:
1110048B16Rik; 2010203A17Rik; AF6q21; AF6q21 protein; C76856; Fkhr2; FKHRL1; FKHRL1P2; forkhead box O3; forkhead box O3a; forkhead box O3A transcription factor; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO2; FOXO3; FOXO-3; FOXO3A

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2309, 294515, 56484

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43524, Q9WVH4

Gene Symbols:
FOXO3

Immunogen:
A synthesized peptide derived from human FOXO3(Accession O43524), corresponding to amino acid residues around phosphorylated Ser318.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118695

--


Antigen:
Phospho-HTRA2 (Ser212)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTRA2

Gene Alias:
AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27429, 297376, 64704

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43464, Q9JIY5

Gene Symbols:
HTRA2

Immunogen:
A synthesized peptide derived from human HTRA2(Accession O43464), corresponding to amino acid residues around phosphorylated Ser212.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG