PIPA5118691

Phospho-Cyclin B1 (Ser133) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5118691-Each-of-1 In Stock ₹ 41,539.38

PIPA5118691 - Each of 1

₹ 41,539.38

In Stock

Quantity

1

Base Price: ₹ 41,539.38

GST (18%): ₹ 7,477.088

Total Price: ₹ 49,016.468

Antigen

Phospho-Cyclin B1 (Ser133)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ccnb1

Gene Alias

Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species

Rabbit

Purification Method

sequential chromatography

Regulatory Status

RUO

Gene ID (Entrez)

25203, 268697, 891

Content And Storage

-20°C

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P14635, P24860, P30277

Gene Symbols

Ccnb1

Immunogen

A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser133.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Antibody detects endogenous levels of Cyclin B1 only when phosphorylated at Ser133
  • Cyclins bind to and regulate the activity of the Cyclin dependent protein kinases (CDKs)
  • Cyclin B1 or CCNB1 is a regulatory protein involved in mitosis
  • It is essential for the control of the cell cycle at the G2/M transition
  • Cyclin B1 complexes with p34 (cdc2) to form the maturation-promoting factor (MPF)
  • Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase
  • Cyclin B1 is not ubiquitinated during G2/M phase, resulting in its steady accumulation during G2 phase, followed by abrupt APC dependent destruction at the end of mitosis
  • Destruction of Cyclin B1 is required for cell cycle progression
  • Cyclin B1 is overexpressed in various cancers, including breast, prostate, and non-small cell lung cancer.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA5118691

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Antigen:
Phospho-Cyclin B1 (Ser133)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ccnb1

Gene Alias:
Ccn-2; CCNB; Ccnb1; Ccnb1-rs1; Ccnb1-rs13; Cycb; Cycb1; Cycb1-rs1; Cycb-4; Cycb-5; cyclin B; cyclin B1; cyclin B1, related sequence 1; cyclin B1, related sequence 13; G2/mitotic-specific cyclin B1; G2/mitotic-specific cyclin-B1; I79_013589; OTTHUMP00000221981; OTTHUMP00000223023

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25203, 268697, 891

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P14635, P24860, P30277

Gene Symbols:
Ccnb1

Immunogen:
A synthesized peptide derived from human CCNB1(Accession P14635), corresponding to amino acid residues around phosphorylated Ser133.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118692

--


Antigen:
Phospho-FOXO3A (Ser318)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FOXO3

Gene Alias:
1110048B16Rik; 2010203A17Rik; AF6q21; AF6q21 protein; C76856; Fkhr2; FKHRL1; FKHRL1P2; forkhead box O3; forkhead box O3a; forkhead box O3A transcription factor; forkhead box protein O3; forkhead homolog (rhabdomyosarcoma) like 1; forkhead in rhabdomyosarcoma-like 1; forkhead protein FKHR2; forkhead, Drosophila, homolog of, in rhabdomyosarcoma-like 1; FOXO2; FOXO3; FOXO-3; FOXO3A

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2309, 294515, 56484

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43524, Q9WVH4

Gene Symbols:
FOXO3

Immunogen:
A synthesized peptide derived from human FOXO3(Accession O43524), corresponding to amino acid residues around phosphorylated Ser318.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118695

--


Antigen:
Phospho-HTRA2 (Ser212)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HTRA2

Gene Alias:
AI481710; High temperature requirement protein A2; HtrA serine peptidase 2; HtrA2; HtrA-like serine protease; mnd2; motor neuron degeneration 2; OMI; Omi stress-regulated endoprotease; PARK13; protease, serine, 25; Prss25; Serine protease 25; serine protease HTRA2, mitochondrial; serine protease OMI; serine proteinase OMI

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
27429, 297376, 64704

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O43464, Q9JIY5

Gene Symbols:
HTRA2

Immunogen:
A synthesized peptide derived from human HTRA2(Accession O43464), corresponding to amino acid residues around phosphorylated Ser212.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA5118696

--


Antigen:
Phospho-JDP2 (Thr148)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JDP2

Gene Alias:
c-Jun dimerization protein 2; Jdp2; Jdp-2; Jun dimerization protein 2; Jundm2; Jundp2; progesterone receptor co-activator; TIF

Host Species:
Rabbit

Purification Method:
sequential chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116674, 122953, 81703

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P97875, Q78E65, Q8WYK2

Gene Symbols:
JDP2

Immunogen:
A synthesized peptide derived from human JDP2 around the phosphorylation site of Thr148.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG