PIPA5119613
TAK1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5119613-Each-of-1 | In Stock | ₹ 43,079.46 |
PIPA5119613 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 43,079.46
GST (18%): ₹ 7,754.303
Total Price: ₹ 50,833.763
Antigen
TAK1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
MAP3K7
Gene Alias
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26409, 313121, 6885
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot
Concentration
1.06 mg/mL
Formulation
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.
O43318, P0C8E4, Q62073
Gene Symbols
MAP3K7
Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human TAK1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Store as concentrated solution
- Centrifuge briefly prior to opening vial
- For short-term storage (1-2 weeks), store at 4°C
- For long-term storage, aliquot and store at -20°C or below
- Avoid multiple freeze-thaw cycles
- TAK1 (also known as MAP3K7), a part of the serine/threonine kinase family, is a versatile protein with many signaling functions
- Originally identified as a TGF- beta-activated kinase, TAK1 interacts with TGF- beta-receptor and TRAF6 to modulate TGF- beta activation of JNK and p38
- It has additional roles in activation of p38 and JNK through Wnt, BMP, and activin signaling pathways as well in response to thyroid hormone, osmotic stress, endothelin, and ephrine
- Through activation of von Hippel-Lindau tumor suppressor expression, TAK1 represses PDGF-B, integrin beta1 and integrin beta5, promoting proper wound healing
- TAK1 also plays an essential role in IKK activation in numerous signaling pathways including IL-1, IL-6, IL-18, TNF, CD40, TLR, and RIG-I
- Activation of the TAK1-IKK pathway requires TAB2/3 and ubiquitination
- In this process, TAB2/3 binds to the C-terminal region of TAK1 and becomes polyubiquitinated, TAK1 is autophosphorylated at Thr178, Thr184, Thr187 and Ser192, and finally TAK1 phosphorylates IKK- beta
- Additionally, TAK1 represses human telomerase reverse transcriptase suggesting a role in regulation of cell lifespan.
Compare Similar Items
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Antigen: TAK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAP3K7
Gene Alias: B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26409, 313121, 6885
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1.06 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O43318, P0C8E4, Q62073
Gene Symbols: MAP3K7
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human TAK1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TAK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAP3K7
Gene Alias:
B430101B05; C87327; hypothetical protein LOC553788; I79_000697; M3K7; map3k7; map3k7.L; MAPKKK; MEKK7; mitogen activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7; mitogen-activated protein kinase kinase kinase 7 L homeolog; RP1-154G14.1; si:ch211-225h9.1; Tak1; TAK1z; TGF1a; TGF-beta activated kinase 1; TGF-beta-activated kinase 1; TGF-beta-activated kinase TAK1; transforming growth factor beta-activated kinase 1; transforming growth factor-beta-activated kinase 1; XELAEV_18027270mg; xTAK1; zgc:110612
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26409, 313121, 6885
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1.06 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O43318, P0C8E4, Q62073
Gene Symbols:
MAP3K7
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human TAK1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM119
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM119
Gene Alias: AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 231633
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: Q8R138
Gene Symbols: TMEM119
Immunogen: Recombinant protein encompassing a sequence within the center region of mouse TMEM119. The exact sequence is proprietary.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM119
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM119
Gene Alias:
AW208946; BC025600; OBIF; Osteoblast induction factor; PSEC0199; Tmem119; Transmembrane protein 119; UNQ731/PRO1415
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
231633
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
Q8R138
Gene Symbols:
TMEM119
Immunogen:
Recombinant protein encompassing a sequence within the center region of mouse TMEM119. The exact sequence is proprietary.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TOMM7
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TOMM7
Gene Alias: 1110020J08Rik; 6.2 kd protein; AD-014; AW047273; mitochondrial import receptor subunit TOM7 homolog; TOM7; TOMM07; TOMM7; Translocase of outer membrane 7 kDa subunit homolog; translocase of outer mitochondrial membrane 7; translocase of outer mitochondrial membrane 7 homolog; translocase of outer mitochondrial membrane 7 homolog (yeast)
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 54543
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q9P0U1
Gene Symbols: TOMM7
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM7.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TOMM7
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TOMM7
Gene Alias:
1110020J08Rik; 6.2 kd protein; AD-014; AW047273; mitochondrial import receptor subunit TOM7 homolog; TOM7; TOMM07; TOMM7; Translocase of outer membrane 7 kDa subunit homolog; translocase of outer mitochondrial membrane 7; translocase of outer mitochondrial membrane 7 homolog; translocase of outer mitochondrial membrane 7 homolog (yeast)
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
54543
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q9P0U1
Gene Symbols:
TOMM7
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human TOMM7.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: USP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: USP1
Gene Alias: Deubiquitinating enzyme 1; EMBL:AAH92574.1, ECO:0000312; hUBP; MGC137005 protein; RGD:1306461}; ubiquitin carboxyl terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1-like protein; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1; UBP; usp1; usp1 {ECO:0000312
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 7398
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.77 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.: O94782
Gene Symbols: USP1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human USP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
USP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
USP1
Gene Alias:
Deubiquitinating enzyme 1; EMBL:AAH92574.1, ECO:0000312; hUBP; MGC137005 protein; RGD:1306461}; ubiquitin carboxyl terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1; ubiquitin carboxyl-terminal hydrolase 1-like protein; ubiquitin specific peptidase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1; UBP; usp1; usp1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
7398
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.77 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300; pH 7
Gene Accession No.:
O94782
Gene Symbols:
USP1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human USP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG