PIPA5142859
LCK Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA5142859-Each-of-1 | In Stock | ₹ 38,758.68 |
PIPA5142859 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 38,758.68
GST (18%): ₹ 6,976.562
Total Price: ₹ 45,735.242
Antigen
LCK
Classification
Polyclonal
Conjugate
Unconjugated
Gene
LCK
Gene Alias
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species
Goat
Purification Method
Ammonium sulfate precipitation
Regulatory Status
RUO
Gene ID (Entrez)
100233188, 313050, 3932
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Isotype
IgG
Applications
Western Blot
Concentration
0.5 mg/mL
Formulation
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.
P06239, Q01621
Gene Symbols
LCK
Immunogen
Peptide with sequence C-RNGSEVRDPLVTYE.
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Porcine, Rat
Form
Liquid
Related Products
Description
- Additional Information: This antibody is not expected to cross-react with other tyrosine protein kinases
- This antibody is tested in Peptide ELISA: antibody detection limit dilution 1:16,000
- LCK is a member of the Src-family tyrosine kinase, which are essential for signaling through the T-cell receptor (TCR) complex
- Upon TCR triggering, LCK phosphorylates the ITAM motives in its zeta subunits establishing binding sites for the SH2 domains of the tyrosine kinase ZAP70, which is also phosphorylated by LCK and activated to generate subsequent signaling platforms by phosphorylation of adaptor LAT
- The majority of LCK is localized to the plasma membrane, however, there is also a significant fraction associated with the Golgi apparatus which may contribute to Raf activation under conditions of weak stimulation through the TCR
- LCK contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively
- LCK is also involved in the regulation of apoptosis induced by various stimuli, but not by the death receptors
- Diseases associated with LCK include Immunodeficiency 22 and CD45 deficiency
- Alternatively splice variants of the LCK gene encoding different isoforms of the protein have been found.
Compare Similar Items
Show Difference
Antigen: LCK
Classification: Polyclonal
Conjugate: Unconjugated
Gene: LCK
Gene Alias: EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 100233188, 313050, 3932
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P06239, Q01621
Gene Symbols: LCK
Immunogen: Peptide with sequence C-RNGSEVRDPLVTYE.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Porcine, Rat
Form: Liquid
Antigen:
LCK
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
LCK
Gene Alias:
EC 2.7.10.2; Hck-3; IMD22; kinase Lck; Lck; LCK proto-oncogene, Src family tyrosine kinase; Lck1; Lcktkr; leukocyte C-terminal Src kinase; LSK; Lskt; Lsk-t; Lymphocyte cell-specific protein-tyrosine kinase; lymphocyte protein tyrosine kinase; lymphocyte-specific protein tyrosine kinase; OTTHUMP00000008640; OTTHUMP00000008740; OTTHUMP00000008741; p56(LSTRA) protein-tyrosine kinase; p56<lck>; p56lck; p56-LCK; pp58lck; Protein YT16; Proto-oncogene Lck; Proto-oncogene tyrosine-protein kinase LCK; RP4-675E8.4; t cell-specific protein-tyrosine kinase; T-lymphocyte specific protein tyrosine kinase p56lck; tyr; tyrosine-protein kinase Lck; YT16
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
100233188, 313050, 3932
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P06239, Q01621
Gene Symbols:
LCK
Immunogen:
Peptide with sequence C-RNGSEVRDPLVTYE.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Porcine, Rat
Form:
Liquid
Antigen: JNK2 beta
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mapk9
Gene Alias: __
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 26420, 5601
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P45984, Q9WTU6
Gene Symbols: Mapk9
Immunogen: Peptide with sequence C-EMVLHKVLFPGRDY.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
JNK2 beta
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Mapk9
Gene Alias:
__
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
26420, 5601
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P45984, Q9WTU6
Gene Symbols:
Mapk9
Immunogen:
Peptide with sequence C-EMVLHKVLFPGRDY.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: STAT5 alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: STAT5A
Gene Alias: AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 20850, 6776
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P42229, P42230
Gene Symbols: STAT5A
Immunogen: Peptide with sequence C-DSRLSPPAGLFTSAR.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Form: Liquid
Antigen:
STAT5 alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
STAT5A
Gene Alias:
AA959963; mammary gland factor; mammary gland factor STAT5A; mammary gland factor; transcription factor; Mgf; Mpf; signal transducer and activator of transcription 5; signal transducer and activator of transcription 5a; signal transducer and activator of transcription factor 5A; STAT; STAT5; STAT5A; STAT5A, Mammary Gland Factor; STAT5A/MGF; STAT5B; STATA5
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
20850, 6776
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P42229, P42230
Gene Symbols:
STAT5A
Immunogen:
Peptide with sequence C-DSRLSPPAGLFTSAR.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Form:
Liquid
Antigen: Zap-70
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ZAP70
Gene Alias: 70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD
Host Species: Goat
Purification Method: Ammonium sulfate precipitation
Regulatory Status: RUO
Gene ID (Entrez): 7535
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Isotype: IgG
Applications: Immunoprecipitation, Western Blot
Concentration: 0.5 mg/mL
Formulation: TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.: P43403
Gene Symbols: ZAP70
Immunogen: Peptide with sequence C-SDGYTPEPARITSPD.
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Form: Liquid
Antigen:
Zap-70
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ZAP70
Gene Alias:
70 kDa zeta-associated protein; 70 kDa zeta-chain associated protein; ADMIO2; EC 2.7.10.2; FLJ17670; FLJ17679; I79_004087; IMD48; kinase ZAP70; mrtle; mur; Selective T cell defect; Srk; STCD; STD; syk-related protein tyrosine kinase; syk-related tyrosine kinase; Tyrosine-protein kinase ZAP-70; Tyrosine-protein kinase ZAP-70;TZK; TZK; ZA70; Zap70; ZAP-70; Zeta chain associated protein kinase 70kDa; zeta chain of T cell receptor associated protein kinase; zeta chain of T cell receptor associated protein kinase 70; zeta chain of T cell receptor associated protein kinase 70kDa; zeta-chain (TCR) associated protein kinase; zeta-chain (TCR) associated protein kinase 70; zeta-chain (TCR) associated protein kinase 70kDa; zeta-chain associated protein kinase 70kDa; zeta-chain associated protein kinase, 70kD
Host Species:
Goat
Purification Method:
Ammonium sulfate precipitation
Regulatory Status:
RUO
Gene ID (Entrez):
7535
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Isotype:
IgG
Applications:
Immunoprecipitation, Western Blot
Concentration:
0.5 mg/mL
Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P43403
Gene Symbols:
ZAP70
Immunogen:
Peptide with sequence C-SDGYTPEPARITSPD.
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human
Form:
Liquid