PIPA5143699

Phospho-Estrogen Receptor alpha (Tyr537) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA5143699-Each-of-1 In Stock ₹ 44,106.18

PIPA5143699 - Each of 1

₹ 44,106.18

In Stock

Quantity

1

Base Price: ₹ 44,106.18

GST (18%): ₹ 7,939.112

Total Price: ₹ 52,045.292

Antigen

Phospho-Estrogen Receptor alpha (Tyr537)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ESR1

Gene Alias

DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 grou

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13982, 2099, 24890

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P03372, P06211, P19785

Gene Symbols

ESR1

Immunogen

Phospho-ERalpha (Tyr-537) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Tyr-537 in human ERalpha. This sequence is well conserved in rat and mouse ERalpha, and is also well conserved in ERbeta (Tyr-488).

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • The antibody was cross-adsorbed to unphosphorylated ERalpha (Tyr-537) peptide before affinity purification using phospho-ERalpha (Tyr-537) peptide (without carrier)
  • This antibody detects several forms of ERalpha ranging from 66 to 35 kDa* on SDS-PAGE immunoblots of MCF-7 cells treated with pervanadate, and this reactivity is removed after alkaline phosphatase treatment
  • Estrogen Receptors (ER) are members of the steroid/thyroid hormone receptor superfamily of nuclear receptors
  • The estrogen receptor is a ligand-activated transcription factor, that when bound to estrogen hormone, induces a conformational change that allows dimerization and binding to estrogen response elements (ERE) in DNA
  • When bound to EREs, ER can positively or negatively regulate gene transcription through the recruitment of coactivator or corepressor proteins
  • There are two different forms of the estrogen receptor, alpha and beta, encoded by separate genes (ESR1 and ESR2, respectively)
  • Due to alternative RNA splicing, at least 4 estrogen receptor-alpha isoforms are known to exist (Isoform 1 (66 kDa), Isoform 2 (53 kDa), Isoform 3 (47 kDa), Isoform 4 (35 kDa))
  • Estrogen receptors are widely expressed in different tissue types and are essential for sexual development and reproductive function
  • They also play a role in other tissues such as bone
  • Estrogen receptors are involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis.

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Img

Thermo Scientific

PIPA5143699

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Antigen:
Phospho-Estrogen Receptor alpha (Tyr537)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ESR1

Gene Alias:
DKFZp686N23123; ER; Er alpha; ER36; ERa; ERalpha; ER-alpha; ERalpha protein; ESR; esr 1; Esr1; esr-1; ESRA; Estr; Estra; Estradiol receptor; estrogen nuclear receptor alpha; Estrogen receptor; estrogen receptor 1; estrogen receptor 1 (alpha); estrogen receptor alpha; estrogen receptor alpha c-terminus splice variant 1-2; estrogen receptor alpha E1-E2-1-2; estrogen receptor alpha E1-N2-E2-1-2; estrogen receptor alpha splice variant, CTERP-1; estrogen receptor alpha splice variant, ERalphaDup5; estrogen receptor alpha splice variant, ERalphai45a; estrogen receptor alpha splice variant, ERalphai45bL; estrogen receptor alpha splice variant, ERalphai45bS; estrogen receptor alpha splice variant, ERalphai45c; estrogen receptor alpha splice variant, ERalphai56; estrogen receptor alpha splice variant, ERalphai67; estrogen receptor alpha variant delta 4; estrogen receptor protein; estrogen receptor, alpha; ESTRR; hER-alpha36; I79_001166; Nr3a1; nuclear receptor; nuclear receptor subfamily 3 grou

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13982, 2099, 24890

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P03372, P06211, P19785

Gene Symbols:
ESR1

Immunogen:
Phospho-ERalpha (Tyr-537) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Tyr-537 in human ERalpha. This sequence is well conserved in rat and mouse ERalpha, and is also well conserved in ERbeta (Tyr-488).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143705

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Antigen:
Histone H2B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2BC21

Gene Alias:
2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102724334, 114483833, 128312, 158983, 24829, 255626, 286436, 291157, 3017, 3018, 319177, 319178, 319181, 319182, 319183, 319184, 319186, 319190, 361247, 440689, 68024, 680312, 691488, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
A0A2R8Y619, O60814, P06899, P0C1H6, P10854, P23527, P33778, P57053, P58876, P62807, P70696, Q00729, Q16778, Q5QNW6, Q64475, Q64478, Q64524, Q6ZWY9, Q7Z2G1, Q8CGP1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880

Gene Symbols:
H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, HIST1H2BA, HIST1H2BD, HIST1H2BJ, HIST1H2BM, HIST1H2BO, LOC102724334

Immunogen:
Histone H2B synthetic peptide (coupled to carrier protein) corresponds to amino acids in the C-terminus of human histone H2B. This sequence is well conserved in rat, mouse, fish, and drosophila histone H2B, and has low homology to other histone family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143707

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Antigen:
Phospho-Histone H2B (Ser36)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H2BW2

Gene Alias:
2610022J01Rik; Acetyl-Histone H2; AV127319; bA317E16.3; CG17949; CG17949-PA; CG33868; CG33868-PA; CG33870; CG33870-PA; CG33872; CG33872-PA; CG33874; CG33874-PA; CG33876; CG33876-PA; CG33878; CG33878-PA; CG33880; CG33880-PA; CG33882; CG33882-PA; CG33884; CG33884-PA; CG33886; CG33886-PA; CG33888; CG33888-PA; CG33890; CG33890-PA; CG33892; CG33892-PA; CG33894; CG33894-PA; CG33896; CG33896-PA; CG33898; CG33898-PA; CG33900; CG33900-PA; CG33902; CG33902-PA; CG33904; CG33904-PA; CG33906; CG33906-PA; CG33908; CG33908-PA; CG33910; CG33910-PA; dJ160A22.3; dJ193B12.2; dJ221C16.3; dJ221C16.6; dJ221C16.8; dJ97D16.4; Dmel\CG17949; Dmel\CG33868; Dmel\CG33870; Dmel\CG33872; Dmel\CG33874; Dmel\CG33876; Dmel\CG33878; Dmel\CG33880; Dmel\CG33882; Dmel\CG33884; Dmel\CG33886; Dmel\CG33888; Dmel\CG33890; Dmel\CG33892; Dmel\CG33894; Dmel\CG33896; Dmel\CG33898; Dmel\CG33900; Dmel\CG33902; Dmel\CG33904; Dmel\CG33906; Dmel\CG33908; Dmel\CG33910; Dmel_CG17949; Dmel_CG33868; Dmel_CG33870; Dmel_CG33872; Dmel_CG33874

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
102724334, 114483833, 128312, 158983, 24829, 255626, 286436, 291157, 3017, 3018, 319177, 319178, 319181, 319182, 319183, 319184, 319186, 319190, 361247, 440689, 68024, 680312, 691488, 8339, 8340, 8341, 8342, 8345, 8346, 8347, 8348, 8349, 85236, 8970

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
A0A2R8Y619, O60814, P06899, P0C1H6, P10854, P23527, P33778, P57053, P58876, P62807, P70696, Q00729, Q16778, Q5QNW6, Q64475, Q64478, Q64524, Q6ZWY9, Q7Z2G1, Q8CGP1, Q8N257, Q93079, Q96A08, Q99877, Q99879, Q99880

Gene Symbols:
H2B, H2bc1, H2BC10, H2BC11, H2BC12, H2BC13, H2BC14, H2BC15, H2BC17, H2bc18, H2BC21, H2BC3, H2BC4, H2BC5, H2BC8, H2BC9, H2BE1, H2BU1, H2BW1, H2BW2, HIST1H2BA, HIST1H2BD, HIST1H2BJ, HIST1H2BM, HIST1H2BO, LOC102724334

Immunogen:
Phospho-Histone H2B (Ser-36) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding Ser-36 in human histone H2B. This sequence is well conserved in most isoforms of rat and mouse histone H2B, and has low homology to other histone family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143708

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Antigen:
Phospho-Histone H4 (Tyr72)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
H4C1

Gene Alias:
BcDNA:RH52884; BUR5; CELE_T10C6.11; CG31611; CG3379; CG3379-PA; CG3379-PB; CG3379-PC; CG3379-PD; CG33869; CG33871; CG33873; CG33875; CG33877; CG33879; CG33881; CG33883; CG33885; CG33887; CG33889; CG33891; CG33893; CG33895; CG33897; CG33899; CG33901; CG33903; CG33905; CG33907; CG33909; Dmel\CG3379; Dmel_CG3379; F07B7.11; F07B7.4; F45F2.12; FBtr0082962; FO108; germinal histone H4; H1ft; H4; H4 clustered histone 11; H4 clustered histone 2; H4 histone family, member A; H4 histone family, member I; H4 histone family, member J; H4 histone family, member M; H4 histone family, member N; H4 histone, family 2; H4.1; H4/A; H4/B; H4/C; H4/D; H4/E; H4/G; H4/H; H4/I; H4/J; H4/K; H4/M; H4/N; H4/O; H4/p; H4-12; H4-16; H4-53; H4c1; H4C11; H4c12; H4C13; H4c14; H4C15; H4C2; H4c3; H4C4; H4C5; H4c6; H4c8; H4C9; H4f16; H4F2; H4FA; H4FB; H4FC; H4FD; H4FE; H4FG; H4FH; H4FI; H4FJ; H4FK; H4FM; H4FN; H4FO; H4ft; H4M; H4r; HHF1; HHF2; HHT1; HHT2; his-20; his-22; His4; his-4; His4:CG31611; His4:CG33869; His4:CG338

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
121504, 319158, 326619, 326620, 679983, 8294, 8359, 8363, 8366, 8367, 8370, 97122

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
∽1 mg/mL

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P62805, P62806

Gene Symbols:
H4-16, H4C1, H4C11, H4C14, H4C2, H4C5, H4C9, HIST1H4A

Immunogen:
Phospho-Histone H4 (Tyr-72) synthetic peptide (coupled to carrier) corresponding to amino acids surrounding Tyr-72 in human histone H4. This site is well conserved in rat and mouse histone H4, but the site is not found in other histone family members.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid