PIPA5143733

Phospho-p130Cas (Tyr751) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA5143733-Each-of-1 In Stock ₹ 44,106.18

PIPA5143733 - Each of 1

₹ 44,106.18

In Stock

Quantity

1

Base Price: ₹ 44,106.18

GST (18%): ₹ 7,939.112

Total Price: ₹ 52,045.292

Antigen

Phospho-p130Cas (Tyr751)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

BCAR1

Gene Alias

AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12927, 25414, 9564

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Isotype

IgG

Applications

Western Blot

Concentration

Lot-Specific

Formulation

PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.

P56945, Q61140, Q63767

Gene Symbols

BCAR1

Immunogen

Phospho-p130 Cas (Tyr-751) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 751 in rat p130 Cas. This rat sequence is the same as Tyr-653 in human p130 Cas and Tyr-657 in mouse p130 Cas.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Form

Liquid

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Description

  • This antibody was cross-adsorbed to phospho-tyrosine coupled to agarose and to phospho-p130 Cas (Tyr-762) peptide before affinity purification using phospho-p130 Cas (Tyr-751) peptide (without carrier)
  • The antibody detects a 130 kDa* protein corresponding to the molecular mass of phosphorylated p130 Cas on SDS-PAGE immunoblots of pervanadate treated human endothelial and A431 cells, but is not observed in control cells
  • The p130Cas (Cas for Crk-associated substrate) is a common cellular target of phosphorylation signal via v-Crk and v-Src oncoproteins
  • p130Cas has a unique structure that contains a Src homology (SH)-3 domain followed by multiple YXXP motifs and a proline-rich regionp130Cas is implicated in a variety of biological processes including cell adhesion, cell migration, growth factor stimulation, cytokine receptor engagement and bacterial infection
  • Physiological functions of p130Cas include cardiovascular development, actin filament assembly and Src-induced cell transformation.

Compare Similar Items

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Img

Thermo Scientific

PIPA5143733

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Antigen:
Phospho-p130Cas (Tyr751)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
BCAR1

Gene Alias:
AI385681; BCA1; Bcar1; BCAR1 scaffold protein, Cas family member; BCAR1, Cas family scaffold protein; BCAR1, Cas family scaffolding protein; breast cancer anti-estrogen resistance 1; breast cancer anti-estrogen resistance protein 1; Cas; Cas scaffolding protein family member 1; CAS1; CASS1; CRKAS; CRK-associated substrate; Crk-associated substrate p130Cas; OTTHUMP00000174941; p130 Cas; P130CAS; p130Cas (pTyr410); p130Cas (pY410); p130Cas phospho; phospho p130Cas; v-crk-associated tyrosine kinase substrate

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12927, 25414, 9564

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P56945, Q61140, Q63767

Gene Symbols:
BCAR1

Immunogen:
Phospho-p130 Cas (Tyr-751) synthetic peptide (coupled to KLH) corresponding to amino acid residues around tyrosine 751 in rat p130 Cas. This rat sequence is the same as Tyr-653 in human p130 Cas and Tyr-657 in mouse p130 Cas.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

Thermo Scientific

PIPA5143736

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Antigen:
Phospho-Paxillin (Ser83)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19303

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
Q8VI36

Gene Symbols:
PXN

Immunogen:
Phospho-Paxillin (Ser-83) synthetic peptide (coupled to KLH) corresponding to amino acid residues around serine 83 of mouse paxillin. This sequence is highly conserved in rat and human paxillin and is also found in all isoforms (a, b, g) of paxillin.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Mouse

Form:
Liquid

Img

Thermo Scientific

PIPA5143739

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Antigen:
Phospho-Paxillin (Thr538)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PXN

Gene Alias:
adaptor protein; AW108311; AW123232; FLJ16691; hCG_1778014; I79_001229; myocardial ischemic preconditioning associated protein 7; Pax; PAX-1; PAXI; Paxillin; paxillin a; paxillin alpha; pxn; pxna; testicular tissue protein Li 134; TGFB1I1; transforming growth factor beta 1 induced transcript 1; wu:fw71f12

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
19303, 360820, 5829

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
P49023, Q66H76, Q8VI36

Gene Symbols:
PXN

Immunogen:
Phospho-Paxillin (Thr-538) synthetic peptide (coupled to KLH) corresponding to amino acid residues around threonine 538 from human paxillin a. This sequence is highly conserved in rat and mouse paxillin and is also found in the other paxillin isoforms (b & g).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid

Img

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PIPA5143740

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Antigen:
Phospho-PDPK1 (Tyr9)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Pdpk1

Gene Alias:
3-phosphoinositide dependent protein kinase 1; 3-phosphoinositide dependent protein kinase-1; 3-phosphoinositide-dependent protein kinase 1; 3-phosphoinositide-dependent protein kinase 2 pseudogene; HGNC:8809; hPDK1; isoenzyme 1; kinase isoenzyme 1; lipoamide; mPDK1; OTTHUMP00000174525; OTTHUMP00000205076; PDK1; PDPK1; PDPK2; PDPK2P; Pkb kinase; PkB kinase like gene 1; PkB-like 1; PRO0461; Protein kinase B kinase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18607, 5170, 81745

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Isotype:
IgG

Applications:
Immunocytochemistry, Western Blot

Concentration:
Lot-Specific

Formulation:
PBS with 1mg/mL BSA, 50% glycerol and 0.05% sodium azide

Gene Accession No.:
O15530, O55173, Q9Z2A0

Gene Symbols:
Pdpk1

Immunogen:
Phospho-PDK1 (Tyr-9) synthetic peptide (coupled to carrier protein) corresponds to amino acids surrounding tyrosine 9 in human PDK1. This sequence is highly conserved in rat and mouse PDK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Form:
Liquid