PIPA517913
Caspase 9 (Cleaved Asp315) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA517913-Each-of-1 | In Stock | ₹ 50,138.16 |
PIPA517913 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 50,138.16
GST (18%): ₹ 9,024.869
Total Price: ₹ 59,163.029
Antigen
Caspase 9 (Cleaved Asp315)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP9
Gene Alias
APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
842
Content And Storage
-20°C
Form
Liquid
Applications
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration
6 μg/mL
Formulation
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.
P55211
Gene Symbols
CASP9
Immunogen
Synthetic peptide corresponding to residues surrounding Asp315 of human caspase-9
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- It is not recommended to aliquot this antibody
- This antibody was orginally validated as part of a Thermo Scientific Cellomics High Content Screening Kit
- The antibody sold separately may have slightly different performance and may need to be further optimized for the best results
- Caspase 9 (ICE-like apoptotic protease 6, ICE LAP6, apoptotic protease Mch6, apoptotic protease activating factor 3, Apaf3) is a member of the peptidase family C14 that contains a CARD domain
- Caspases are cysteine proteases, expressed as inactive precursors, that mediate apoptosis by proteolysis of specific substrates
- Caspase 9 is active as a heterotetramer, is present in the cytosol and, upon activation, translocates to the mitochondria
- Caspase 9 is involved in the caspase activation cascade responsible for apoptosis execution and cleaves/activates Caspase 3 and Caspase 6
- Further, Caspase 9 is involved in the activation cascade of caspases responsible for apoptosis execution
- Binding of caspase-9 to Apaf- 1 leads to activation of the protease which then cleaves and activates caspase-3
- Caspase 9 promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner, and proteolytically cleaves poly(ADP- ribose) polymerase (PARP)
- Caspase 9 is expressed in variety of human tissues
- An isoform of rat Caspase-9 has been identified in which the C terminus of full-length Caspase-9 is replaced with an alternative peptide sequence
- Mutations in Caspase 9 affect brain development
- In mice, insufficient Caspase 9 have resulted in abnormal cerebrum development and neuron development
- In humans, dysfunctional Caspase 9 expression vary from tissue to tissue
- Low levels of Caspase 9 may play a role in cancer development and neurodegenerative diseases such as Alzheimer’s Disease (AD).
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Antigen: Caspase 9 (Cleaved Asp315)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP9
Gene Alias: APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 842
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration: 6 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P55211
Gene Symbols: CASP9
Immunogen: Synthetic peptide corresponding to residues surrounding Asp315 of human caspase-9
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Caspase 9 (Cleaved Asp315)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP9
Gene Alias:
APAF3; APAF-3; apoptosis-related cysteine protease; apoptotic protease activating factor 3; apoptotic protease MCH-6; Apoptotic protease-activating factor 3; cas9; CASP9; CASP-9; caspase 9; caspase 9, apoptosis-related cysteine peptidase; caspase-9; Caspase-9 subunit p10; Caspase-9 subunit p35; ICE-LAP6; ICE-like apoptotic protease 6; MCH6; OTTHUMP00000002324; PPP1R56; protein phosphatase 1, regulatory subunit 56
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
842
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunoprecipitation, Western Blot
Concentration:
6 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P55211
Gene Symbols:
CASP9
Immunogen:
Synthetic peptide corresponding to residues surrounding Asp315 of human caspase-9
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-beta Catenin (Thr41, Ser45)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CTNNB1
Gene Alias: armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12387, 1499, 397657, 477032
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: B6V8E6, P35222, Q02248
Gene Symbols: CTNNB1
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pThr41 and pSer45 of human β-catenin
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Canine, Human, Mouse, Non-human Primate, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-beta Catenin (Thr41, Ser45)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CTNNB1
Gene Alias:
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12387, 1499, 397657, 477032
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
B6V8E6, P35222, Q02248
Gene Symbols:
CTNNB1
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr41 and pSer45 of human β-catenin
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Canine, Human, Mouse, Non-human Primate, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-eNOS (Ser1177)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NOS3
Gene Alias: 2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 287024, 397557, 4846
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: 79 μg/mL
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: P29473, P29474, Q28969
Gene Symbols: NOS3
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer1177 of human eNOS
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Bovine, Human, Porcine
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-eNOS (Ser1177)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NOS3
Gene Alias:
2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
287024, 397557, 4846
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
79 μg/mL
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
P29473, P29474, Q28969
Gene Symbols:
NOS3
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer1177 of human eNOS
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Bovine, Human, Porcine
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-MSK1 (Ser376)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rps6ka5
Gene Alias: 3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 314384, 73086, 9252
Content And Storage: -20°C
Form: Liquid
Applications: Western Blot
Concentration: __
Formulation: 0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.: O75582, Q8C050
Gene Symbols: Rps6ka5
Immunogen: Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human MSK1
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-MSK1 (Ser376)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rps6ka5
Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
314384, 73086, 9252
Content And Storage:
-20°C
Form:
Liquid
Applications:
Western Blot
Concentration:
__
Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5
Gene Accession No.:
O75582, Q8C050
Gene Symbols:
Rps6ka5
Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human MSK1
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG