PIPA517916

Phospho-beta Catenin (Thr41, Ser45) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA517916-Each-of-1 In Stock ₹ 44,705.10

PIPA517916 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-beta Catenin (Thr41, Ser45)

Classification

Polyclonal

Formulation

0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.

B6V8E6, P35222, Q02248

Gene Symbols

CTNNB1

Immunogen

Synthetic phosphopeptide corresponding to residues surrounding pThr41 and pSer45 of human β-catenin

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Canine, Human, Mouse, Non-human Primate, Porcine

Product Type

Antibody

Isotype

IgG

Applications

Western Blot

Conjugate

Unconjugated

Gene

CTNNB1

Gene Alias

armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

12387, 1499, 397657, 477032

Content And Storage

-20°C

Form

Liquid

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Description

  • It is not recommended to aliquot this antibody
  • Beta-catenin, an adherens junction (AJ) protein, was originally identified as a component of cell-cell adhesion structures
  • AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells
  • Beta-catenin interacts with the cytoplasmic domain of E-cadherin and links E-cadherin to alpha-catenin, which in turn mediates anchorage of the E-cadherin complex to the cortical actin cytoskeleton
  • Studies show that Beta-catenin also binds to another cytoskeletal complex containing the adenomatous polyposis coli protein and microtubules, and interacts with several signaling pathways that include tyrosine kinases, phosphatases and Wnt/Wingless
  • The interplay between beta-catenin, cytoskeletal complexes and signaling pathways may regulate morphogenesis
  • Beta-catenin is expressed in several hair follicle cell types, basal and peripheral matrix cells, and cells of the outer and inner root sheats
  • A pathological role of beta-catenin has been identified in pilomatrixoma (PTR), medulloblastoma (MDB), colorectal cancer (CRC), ovarian cancer, and tumor development
  • In the nucleus, beta-catenin serves to co activate a family of Lef/Tcf transcription factors that stimulate transcription of target genes including those encoding cyclin D and c-myc that promote cell proliferation
  • The influence on cell proliferation is the molecular basis for the role of beta-catenin in tumorgenesis, specifically, solid tumors of the breast, colon, liver, lung, gastric, prostate, and skin.

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Thermo Scientific

PIPA517916

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Antigen:
Phospho-beta Catenin (Thr41, Ser45)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
B6V8E6, P35222, Q02248

Gene Symbols:
CTNNB1

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pThr41 and pSer45 of human β-catenin

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Canine, Human, Mouse, Non-human Primate, Porcine

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
CTNNB1

Gene Alias:
armadillo; armadillo homolog; Bcatenin; b-catenin; beta 1 88kDa; beta catenin; Betacatenin; beta-catenin; beta-catenin 1; Bfc; C20orf33; Cadherin associated protein; catenin; catenin (cadherin associated protein), beta 1; catenin (cadherin associated protein), beta 1, 88kDa; catenin (cadherin-associated protein) beta 1; catenin (cadherin-associated protein), beta 1; catenin (cadherin-associated protein), beta 1, 88kDa; Catenin b 1; Catenin b1; catenin beta; catenin beta 1; catenin beta 1 L homeolog; Catenin beta1; Catenin beta-1; Catenin β 1; Catenin β1; Catnb; CHBCAT; CTNB1; CTNNB; ctnnb1; ctnnb1.L; ctnnb1-a; ctnnb1-b; dJ633O20.1; DKFZp686D02253; FLJ25606; FLJ37923; id:ibd2058; Mesc; MRD19; NAP; NYD-SP19; OK/SW-cl.35; OTTHUMP00000209289; P14L; PP8304; PRO2286; RP5-1118M15.1; wu:fb73e10; wu:fi81c06; wu:fk25h01; XELAEV_18031149mg; β catenin; βcatenin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
12387, 1499, 397657, 477032

Content And Storage:
-20°C

Form:
Liquid

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PIPA517917

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Antigen:
Phospho-eNOS (Ser1177)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
P29473, P29474, Q28969

Gene Symbols:
NOS3

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer1177 of human eNOS

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Bovine, Human, Porcine

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
NOS3

Gene Alias:
2310065A03Rik; cNOS; Constitutive NOS; Ecnos; EC-NOS; endothelial nitric oxide synthase; endothelial nitric oxide synthase 3; endothelial nitric oxide synthase NOS3; endothelial NOS; eNos; e-NOS; nitric oxide synthase; nitric oxide synthase 3; nitric oxide synthase 3 (endothelial cell); nitric oxide synthase 3 transcript variant eNOS-delta20; nitric oxide synthase 3 transcript variant eNOS-delta20-21; nitric oxide synthase 3 transcript variant eNOS-delta21; nitric oxide synthase 3, endothelial cell; nitric oxide synthase, endothelial; NOS; NOS type III; Nos3; Nos-3; NOSIII; OTTHUMP00000213183

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
287024, 397557, 4846

Content And Storage:
-20°C

Form:
Liquid

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PIPA517918

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Antigen:
Phospho-MSK1 (Ser376)

Classification:
Polyclonal

Formulation:
0.01M HEPES with 0.15M NaCl, 100μg/mL BSA, 50% glycerol and no preservative; pH 7.5

Gene Accession No.:
O75582, Q8C050

Gene Symbols:
Rps6ka5

Immunogen:
Synthetic phosphopeptide corresponding to residues surrounding pSer376 of human MSK1

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
Rps6ka5

Gene Alias:
3110005L17Rik; 6330404E13Rik; 90 kDa ribosomal protein S6 kinase 5; AI854034; kinase MSK1; KS6A5; mitogen and stress-activated protein kinase 1; Msk1; MSPK1; Nuclear mitogen- and stress-activated protein kinase 1; ribosomal protein S6 kinase A5; ribosomal protein S6 kinase alpha-5; ribosomal protein S6 kinase, 90kDa, polypeptide 5; ribosomal protein S6 kinase, polypeptide 5; RLPK; RLSK; Rps6ka5; RSKL; RSK-like protein kinase; S6K-alpha-5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
314384, 73086, 9252

Content And Storage:
-20°C

Form:
Liquid

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PIPA517930

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Antigen:
Tankyrase 2

Classification:
Polyclonal

Formulation:
TBS with 0.5% BSA and 0.02% sodium azide; pH 7.3

Gene Accession No.:
Q9H2K2

Gene Symbols:
TNKS2

Immunogen:
Synthetic peptide sequence (RECOMBINANT2) corresponding to the internal amino acids of TNKS2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Applications:
Western Blot

Conjugate:
Unconjugated

Gene:
TNKS2

Gene Alias:
5430432P15Rik; AA517131; ADP-ribosyltransferase diphtheria toxin-like 6; AI662480; ARTD6; PARP5B; PARP-5b; PARP5C; PARP-5c; pART6; Poly [ADP-ribose] polymerase 5B; Poly [ADP-ribose] polymerase tankyrase-2; Protein poly-ADP-ribosyltransferase tankyrase-2; TANK2; tankyrase 2; tankyrase II; tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2; tankyrase-2; Tankyrase-like protein; tankyrase-related protein; TNKL; tnks 2; TNKS2; TNKS-2; TRF1-interacting ankyrin-related ADP-ribose polymerase 2

Host Species:
Goat

Purification Method:
Ammonium sulfate precipitation

Regulatory Status:
RUO

Gene ID (Entrez):
80351

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid