PIPA534434

PHLPP1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA534434-Each-of-1 In Stock ₹ 47,015.22

PIPA534434 - Each of 1

₹ 47,015.22

In Stock

Quantity

1

Base Price: ₹ 47,015.22

GST (18%): ₹ 8,462.74

Total Price: ₹ 55,477.96

Antigen

PHLPP1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

PHLPP1

Gene Alias

AI836256, Circadian Oscillatory Protein (SCOP), EC 3.1.3.16, hSCOP, KIAA0606, mKIAA0606, PH domain and leucine rich repeat protein phosphatase 1, PH domain leucine-rich repeat protein phosphatase 1, PH domain leucine-rich repeat-containing protein phosphatase 1, PH domain-containing family E member 1, Phlpp, PHLPP1, pleckstrin homology domain containing, family E (with leucine rich repeats) member 1, pleckstrin homology domain-containing family E member 1, pleckstrin homology domain-containing family E protein 1, Plekhe1, PPM3A, protein phosphatase, Mg2+/Mn2+ dependent 3A, SCN circadian oscillatory protein, SCOP, Suprachiasmatic nucleus circadian oscillatory protein

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

23239

Content And Storage

Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 0.02% sodium azide

Gene Accession No.

O60346

Gene Symbols

PHLPP1

Immunogen

An 18 amino acid synthetic peptide near the amino terminus of human PHLPP1

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • A suggested positive control is SW480 cell lysate
  • PA5-34434 can be used with blocking peptide PEP-1476
  • PHLPP1 is a member of the serine/threonine phosphatase family, which are important regulators of Akt serine-threonine kinases (AKT1, AKT2, AKT3) and conventional/novel protein kinase C (PKC) isoforms
  • PHLPP1 and PHLPP2 have a similar domain structure and have been shown to dephosphorylate and inactivate, distinct Akt isoforms, at one of the two critical phosphorylation sites required for activation: Serine473
  • PHLPP2 dephosphorylates AKT1 and AKT3, whereas PHLPP1 is specific for AKT2 and AKT3
  • PHLPP1 promotes apoptosis and may act as a tumor suppressor
  • Increased expression of PHLPP1 may also play a role in obesity and type 2 diabetes by interfering with Akt-mediated insulin signaling.

Compare Similar Items

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Img

Thermo Scientific

PIPA534434

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Antigen:
PHLPP1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PHLPP1

Gene Alias:
AI836256, Circadian Oscillatory Protein (SCOP), EC 3.1.3.16, hSCOP, KIAA0606, mKIAA0606, PH domain and leucine rich repeat protein phosphatase 1, PH domain leucine-rich repeat protein phosphatase 1, PH domain leucine-rich repeat-containing protein phosphatase 1, PH domain-containing family E member 1, Phlpp, PHLPP1, pleckstrin homology domain containing, family E (with leucine rich repeats) member 1, pleckstrin homology domain-containing family E member 1, pleckstrin homology domain-containing family E protein 1, Plekhe1, PPM3A, protein phosphatase, Mg2+/Mn2+ dependent 3A, SCN circadian oscillatory protein, SCOP, Suprachiasmatic nucleus circadian oscillatory protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23239

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O60346

Gene Symbols:
PHLPP1

Immunogen:
An 18 amino acid synthetic peptide near the amino terminus of human PHLPP1

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534435

--


Antigen:
PHLPP2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Phlpp2

Gene Alias:
AI481772; C130044A18Rik; GTPase activating protein and VPS9 domains 1; KIAA0931; PH domain and leucine rich repeat protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase 2; PH domain leucine-rich repeat-containing protein phosphatase-like; PHLPP2; Phlppl; PHLPP-like; PPM3B; protein phosphatase, Mg2+/Mn2+ dependent 3B; RGD1562857

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
23035

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
Q6ZVD8

Gene Symbols:
Phlpp2

Immunogen:
A 20 amino acid synthetic peptide near the carboxy terminus of human PHLPP2

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534436

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Antigen:
EPM2A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
EPM2A

Gene Alias:
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha; epilepsy, progressive myoclonus type 2, Lafora disease (laforin); epilepsy, progressive myoclonus type 2A; epilepsy, progressive myoclonus type 2A, Lafora disease (laforin); EPM2; EPM2A; EPM2A glucan phosphatase, laforin; EPM2A, laforin glucan phosphatase; glucan phosphatase; Glycogen phosphatase; Lafora PTPase; laforin; LAFPTPase; MELF; RP1-28C20.2; Tg(TcraK,TcrbK)TG-BFlv; TG-B

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
114005, 13853, 7957

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
B3EWF7, Q91XQ2, Q9WUA5

Gene Symbols:
EPM2A

Immunogen:
A 17 amino acid synthetic peptide near the carboxy terminus of human EPM2A

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA534437

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Antigen:
Claudin 4

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cldn4

Gene Alias:
Cep-r; claudin 4; CLAUDIN4; claudin-4; CLDN4; Clostridium perfringens enterotoxin receptor; Clostridium perfringens enterotoxin receptor 1; CPER; CPE-R; CPE-receptor; Cpetr; CPETR1; h CPE-receptor; hCPE-R; WBSCR8; Williams-Beuren syndrome chromosomal region 8 protein

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1364

Content And Storage:
Maintain refrigerated at 2-8°C for up to 3 months. For long term storage store at -20°C

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.02% sodium azide

Gene Accession No.:
O14493

Gene Symbols:
Cldn4

Immunogen:
A 17 amino acid synthetic peptide near the carboxy terminus of human CLAUDIN4

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG