PIPA538259
Phospho-beta Arrestin 1 (Ser412) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA538259-Each-of-1 | In Stock | ₹ 42,694.44 |
PIPA538259 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,694.44
GST (18%): ₹ 7,684.999
Total Price: ₹ 50,379.439
Antigen
Phospho-beta Arrestin 1 (Ser412)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ARRB1
Gene Alias
ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
408
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P49407
Gene Symbols
ARRB1
Immunogen
A synthetic phosphopeptide derived from human Arrestin-1 around the phosphorylation site of Ser412 (T-G-SP-P-Q)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Non-human Primate
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Beta Arrestin 1 is a member of a family of proteins widely expressed but especially abundant in the central nervous system
- Serving as an adaptor or scaffold maolecule, beta Arrestin 1 is essential for mitogenic signalling and mediates agonist-dependent desensitization and internalization of Gprotein-coupled receptors (GPCRs, e.g., beta 2-adrenergic receptor)
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs are phosporylated by G-protein receptor kinases (GRKs) on serine residues
- Beta Arrestin 1 in the cytosol is phosphorylated by ERK1&2 on serine412 in a negative feedback mechanism and binds to the phosphorylated receptors at the plasma membrane
- Serine 412 is then dephosphorylated and the GPCRs are internalized, leading to activation of the Ras, Raf, ERK1&2 signaling pathway.
Compare Similar Items
Show Difference
Antigen: Phospho-beta Arrestin 1 (Ser412)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ARRB1
Gene Alias: ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 408
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P49407
Gene Symbols: ARRB1
Immunogen: A synthetic phosphopeptide derived from human Arrestin-1 around the phosphorylation site of Ser412 (T-G-SP-P-Q)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Non-human Primate
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-beta Arrestin 1 (Ser412)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ARRB1
Gene Alias:
ARRB1, ARR1, Beta-arrestin-1, Arrestin beta-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
408
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P49407
Gene Symbols:
ARRB1
Immunogen:
A synthetic phosphopeptide derived from human Arrestin-1 around the phosphorylation site of Ser412 (T-G-SP-P-Q)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Non-human Primate
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-BID (Ser78)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BID
Gene Alias: BH3-interacting domain death agonist, BID, p22 BID
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12122, 637
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P55957, P70444
Gene Symbols: BID
Immunogen: A synthetic phosphopeptide derived from human BID around the phosphorylation site of Ser78 (S-E-SP-Q-E)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-BID (Ser78)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BID
Gene Alias:
BH3-interacting domain death agonist, BID, p22 BID
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12122, 637
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P55957, P70444
Gene Symbols:
BID
Immunogen:
A synthetic phosphopeptide derived from human BID around the phosphorylation site of Ser78 (S-E-SP-Q-E)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Caldesmon (Ser789)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CALD1
Gene Alias: CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 109624, 25687, 800
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: Q05682, Q62736
Gene Symbols: CALD1
Immunogen: A synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789 (V-T-SP-P-T)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Caldesmon (Ser789)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CALD1
Gene Alias:
CAD, CALD1, CDM, L-caldesmon, Non-muscle caldesmon
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
109624, 25687, 800
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
Q05682, Q62736
Gene Symbols:
CALD1
Immunogen:
A synthetic phosphopeptide derived from human Caldesmon around the phosphorylation site of Ser789 (V-T-SP-P-T)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-c-Cbl (Tyr774)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CBL
Gene Alias: E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL, CBL, CBL2, RNF55
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12402, 500985, 867
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P22681, P22682
Gene Symbols: CBL
Immunogen: A synthetic phosphopeptide derived from human CBL around the phosphorylation site of Tyr774 (D-G-YP-D-V)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-c-Cbl (Tyr774)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CBL
Gene Alias:
E3 ubiquitin-protein ligase CBL, Casitas B-lineage lymphoma proto-oncogene, Proto-oncogene c-Cbl, RING finger protein 55, Signal transduction protein CBL, CBL, CBL2, RNF55
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12402, 500985, 867
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P22681, P22682
Gene Symbols:
CBL
Immunogen:
A synthetic phosphopeptide derived from human CBL around the phosphorylation site of Tyr774 (D-G-YP-D-V)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG