PIPA538272

Phospho-FGFR1 (Tyr654) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA538272-Each-of-1 In Stock ₹ 42,694.44

PIPA538272 - Each of 1

₹ 42,694.44

In Stock

Quantity

1

Base Price: ₹ 42,694.44

GST (18%): ₹ 7,684.999

Total Price: ₹ 50,379.439

Antigen

Phospho-FGFR1 (Tyr654)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

FGFR1

Gene Alias

Fibroblast growth factor receptor 1, FGFR-1, 2.7.10.1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, FGFR1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

14182, 2260, 79114

Content And Storage

-20°C

Form

Liquid

Applications

Immunofluorescence, Western Blot

Concentration

1 mg/mL

Formulation

Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.

P11362, P16092, Q04589

Gene Symbols

FGFR1

Immunogen

A synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr654 (D-Y-YP-K-K)

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human, Mouse, Non-human Primate, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • FGFR1 (fibroblast growth factor receptor 1) is a member of the fibroblast growth factor receptor family containing an Ig-like domain and a tyrosine kinase domain
  • FGFR1 has multiple isoforms and is a Type I membrane protein
  • FGFR family members differ from one another in their ligand affinities and tissue distribution
  • A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain
  • The extracellular portion of FGFR1 interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation
  • FGFR1 binds both acidic and basic fibroblast growth factors and is involved in limb induction
  • FGFR1 can be modified by phosphorylation and can bind basic/acidic fibroblast factor depending on the receptor isoform
  • FGFR1 has been shown to interact with N-cadherin and NCAM
  • Four genes encoding for high affinity cell surface FGF receptors (FGFRs) have been identified: FGFR-1, FGFR-2, FGFR-3 and FGFR-4
  • FGFRs are members of the tyrosine kinase family of growth factor receptors
  • At the mRNA level, FGFR1 is highly expressed in developing human tissues including the brain, vascular basement membrane and skin
  • Defects in FGFR1 result in Pfeiffer syndrome associated with craniosynostosis
  • Other defects in FGFR1 are responsible for several diseases which include Pfeiffer syndrome (PS), idiopathic hypogonadotropic hypogonadism (IHH), Kallmann syndrome type 2 (KAL2), osteoglophonic dysplasia (OGD), non-syndromic trigonocephaly, Jackson-Weiss syndrome, Antley-Bixler syndrome
  • Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome.

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Show Difference

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Thermo Scientific

PIPA538272

--


Antigen:
Phospho-FGFR1 (Tyr654)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FGFR1

Gene Alias:
Fibroblast growth factor receptor 1, FGFR-1, 2.7.10.1, Basic fibroblast growth factor receptor 1, BFGFR, bFGF-R-1, Fms-like tyrosine kinase 2, FLT-2, N-sam, Proto-oncogene c-Fgr, CD331, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, FGFR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
14182, 2260, 79114

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunofluorescence, Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P11362, P16092, Q04589

Gene Symbols:
FGFR1

Immunogen:
A synthetic phosphopeptide derived from human FGFR1 around the phosphorylation site of Tyr654 (D-Y-YP-K-K)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Non-human Primate, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538278

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Antigen:
Phospho-HSP20 (Ser16)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
HSPB6

Gene Alias:
Hsp20, heat shock 20 kDa-like protein p20, heat shock protein beta-6, HSPB6

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
126393, 192245, 243912

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
O14558, Q5EBG6, P97541

Gene Symbols:
HSPB6

Immunogen:
A synthetic phosphopeptide derived from human HSP20 around the phosphorylation site of Ser16 (R-A-SP-A-P)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538282

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Antigen:
Phospho-INSR (Tyr1355)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
INSR

Gene Alias:
CD 220, CD220, CD220 antigen, HHF 5, HHF5, human insulin receptor, INSR, INSR, Insulin receptor subunit beta, IR 1, IR, IR-1, IR1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16337, 24954, 3643

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P06213, P15208, P15127

Gene Symbols:
INSR

Immunogen:
A synthetic phosphopeptide derived from human IR around the phosphorylation site of Tyr1355 (R-S-YP-E-E)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA538284

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Antigen:
Phospho-IRAK1 (Thr387)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
IRAK1

Gene Alias:
IL-1 Receceptor Associated Kinase, Interleukin-1 receptor-associated kinase 1, mPLK, IRAK, pelle, Pelle homolog, Pelle

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
16179, 363520, 3654

Content And Storage:
-20°C

Form:
Liquid

Applications:
Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4

Gene Accession No.:
P51617, Q62406

Gene Symbols:
IRAK1

Immunogen:
A synthetic phosphopeptide derived from human IRAK1 around the phosphorylation site of Thr387 (R-G-TP-L-A)

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG