PIPA538343
Phospho-TSC2 (Thr1462) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA538343-Each-of-1 | In Stock | ₹ 42,694.44 |
PIPA538343 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 42,694.44
GST (18%): ₹ 7,684.999
Total Price: ₹ 50,379.439
Antigen
Phospho-TSC2 (Thr1462)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
TSC2
Gene Alias
Tuberin, Tuberous sclerosis 2 protein, TSC2, TSC4
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
22084, 24855, 7249
Content And Storage
-20°C
Form
Liquid
Applications
Immunohistochemistry (Paraffin)
Concentration
1 mg/mL
Formulation
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.
P49815, Q61037, P49816
Gene Symbols
TSC2
Immunogen
A synthetic phosphopeptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462 (G-Y-TP-I-S)
Quantity
100 μg
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- TSC2 (Tuberin, Tuberous sclerosis complex, TSC Complex Subunit 2), is implicated as a tumor suppressor and may function in vesicular transport, play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- TSC2 associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin
- Phosphorylation of tuberin on Ser 939 and Thr 1462 regulates its interaction with hamartin, and is stimulated by various growth factors through the phosphoinositide 3-kinase/Akt pathway
- TSC2 may have a function in vesicular transport, but may also play a role in the regulation of cell growth arrest and in the regulation of transcription mediated by steroid receptors
- Interaction between TSC1 and TSC2 may facilitate vesicular docking
- TSC2 specifically stimulates the intrinsic GTPase activity of the Ras related protein RAP1A and RAB5, suggesting a possible mechanism for its role in regulating cellular growth
- Mutations in TSC2 lead to constitutive activation of RAP1A in tumors and are involved in diseases such as lymphangioleiomyomatosis and TSC2 angiomyolipoma
- Alternative splicing results in transcript variants of three different isoforms of TSC2.
Compare Similar Items
Show Difference
Antigen: Phospho-TSC2 (Thr1462)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TSC2
Gene Alias: Tuberin, Tuberous sclerosis 2 protein, TSC2, TSC4
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 22084, 24855, 7249
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P49815, Q61037, P49816
Gene Symbols: TSC2
Immunogen: A synthetic phosphopeptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462 (G-Y-TP-I-S)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-TSC2 (Thr1462)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TSC2
Gene Alias:
Tuberin, Tuberous sclerosis 2 protein, TSC2, TSC4
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
22084, 24855, 7249
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P49815, Q61037, P49816
Gene Symbols:
TSC2
Immunogen:
A synthetic phosphopeptide derived from human Tuberin/TSC2 around the phosphorylation site of Thr1462 (G-Y-TP-I-S)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-XIAP (Ser87)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: XIAP
Gene Alias: API3, BIR4, BIRC4, Baculoviral IAP repeat-containing protein 4, HILP, IAP-like protein, IAP3, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11798, 331, 63879
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P98170, Q60989, Q9R0I6
Gene Symbols: XIAP
Immunogen: A synthetic phosphopeptide derived from human XIAP around the phosphorylation site of Ser87 (K-V-SP-P-N)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-XIAP (Ser87)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
XIAP
Gene Alias:
API3, BIR4, BIRC4, Baculoviral IAP repeat-containing protein 4, HILP, IAP-like protein, IAP3, Inhibitor of apoptosis protein 3, X-linked IAP, X-linked inhibitor of apoptosis protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11798, 331, 63879
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P98170, Q60989, Q9R0I6
Gene Symbols:
XIAP
Immunogen:
A synthetic phosphopeptide derived from human XIAP around the phosphorylation site of Ser87 (K-V-SP-P-N)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cdc25C (Thr48)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CDC25C
Gene Alias: CDC25M1, Dual specificity phosphatase Cdc25C, EC 3.1.3.48, M-phase inducer phosphatase 3, MPIP3
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12532, 995
Content And Storage: -20°C
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P30307, P48967
Gene Symbols: CDC25C
Immunogen: A synthetic phosphopeptide derived from human CDC25C around the phosphorylation site of Thr48 (P-R-TP-P-V)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cdc25C (Thr48)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CDC25C
Gene Alias:
CDC25M1, Dual specificity phosphatase Cdc25C, EC 3.1.3.48, M-phase inducer phosphatase 3, MPIP3
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12532, 995
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P30307, P48967
Gene Symbols:
CDC25C
Immunogen:
A synthetic phosphopeptide derived from human CDC25C around the phosphorylation site of Thr48 (P-R-TP-P-V)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-Cyclin E (Thr77)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CCNE1
Gene Alias: CCNE, CCNE1, G1/S-specific cyclin E1, E-S
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 12447, 898
Content And Storage: -20°C
Form: Liquid
Applications: Immunocytochemistry, Immunofluorescence
Concentration: 1 mg/mL
Formulation: Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.: P24864, Q61457
Gene Symbols: CCNE1
Immunogen: A synthetic phosphopeptide derived from human Cyclin E1 around the phosphorylation site of Thr77 (I-P-TP-P-D)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-Cyclin E (Thr77)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CCNE1
Gene Alias:
CCNE, CCNE1, G1/S-specific cyclin E1, E-S
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
12447, 898
Content And Storage:
-20°C
Form:
Liquid
Applications:
Immunocytochemistry, Immunofluorescence
Concentration:
1 mg/mL
Formulation:
Dulbecco′s PBS with 150mM NaCl, 50% glycerol and 0.02% sodium azide; pH 7.4
Gene Accession No.:
P24864, Q61457
Gene Symbols:
CCNE1
Immunogen:
A synthetic phosphopeptide derived from human Cyclin E1 around the phosphorylation site of Thr77 (I-P-TP-P-D)
Quantity:
100 μg
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG