PIPA553305
SERPINB2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA553305-Each-of-1 | In Stock | ₹ 47,015.22 |
PIPA553305 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,015.22
GST (18%): ₹ 8,462.74
Total Price: ₹ 55,477.96
Antigen
SERPINB2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
SERPINB2
Gene Alias
HsT1201; Monocyte Arg-serpin; ovalbumin; PAI; Pai2; PAI-2; Pai2a; Placental plasminogen activator inhibitor; Planh2; Plasminogen activator inhibitor 2; plasminogen activator inhibitor 2 type A; Plasminogen activator inhibitor 2, macrophage; plasminogen activator inhibitor, type II; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) peptidase inhibitor, clade B, member 2; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serine (or cysteine) proteinase inhibitor, clade B, member 2; serpin B2; serpin family B member 2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; SERPINB2; Urokinase inhibitor
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
5055
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry
Concentration
0.1 mg/mL
Formulation
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.
P05120
Gene Symbols
SERPINB2
Immunogen
Recombinant protein corresponding to Human PAI2
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TQTKGKIPNL LPEGSVDGDT RMVLVNAVYF KGKWKTPFEK KLNGLYPFRV NSAQRTPVQM MYLREKLNIG YIEDLKAQIL ELPYAGDVSM FLLLPDEIAD VSTGLELLES EITYDKLNKW TSKD Highest antigen sequence identity to the following orthologs: Mouse - 80%, Rat - 77%
- PAI-2 is an inhibitory serpin expressed mainly in keratinocytes, activated monocytes, and placental trophoblasts
- It exists predominantly as a 47 kDa, nonglycosylated, intracellular protein, which can be induced to be secreted as 60 kDa glycoprotein
- The glycosylated and unglycosylated forms of PAI-2 are equally effective as inhibitors of urokinase-type plasminogen activator (uPA), the only established physiological target of this serpin
- PAI-2 has a unique ability to form dormant polymers spontaneously and reversibly under physiological conditions
- The physiological relevance of this property, which is neither a consequence of any mutation in the PAI-2 gene nor associated with any known disorder, is still unclear
- However, it appears that the formation of intracellular, dormant polymers may be important for the controlled release of the inhibitor from PAI-2 producing cells
- Plasma levels of PAI-2 are usually low or undetectable, except during pregnancy and in some forms of monocytic leukemia
- Secretion of PAI-2 from the placenta normally occurs during the third trimester of pregnancy, and accounts for the dramatic increase in PAI-2 levels (up to 250 ng/ml), which are maintained at these levels until postpartum, and then rapidly decline
- In addition to its vital role in protecting the placenta from degradation by uPA and/or uPA-activated proteases, PAI-2 has been shown to be essential for the prevention of metastatic spread of neck, lung and breast cancers
- The beneficial effect of PAI-2 seen in these studies is presumed to stem from its ability to inhibit uPA-dependent cell dissemination
- PAI-2 has also been reported to inhibit keratinocyte proliferation, and to participate in the innate immune response during viral infection.
Compare Similar Items
Show Difference
Antigen: SERPINB2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SERPINB2
Gene Alias: HsT1201; Monocyte Arg-serpin; ovalbumin; PAI; Pai2; PAI-2; Pai2a; Placental plasminogen activator inhibitor; Planh2; Plasminogen activator inhibitor 2; plasminogen activator inhibitor 2 type A; Plasminogen activator inhibitor 2, macrophage; plasminogen activator inhibitor, type II; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) peptidase inhibitor, clade B, member 2; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serine (or cysteine) proteinase inhibitor, clade B, member 2; serpin B2; serpin family B member 2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; SERPINB2; Urokinase inhibitor
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5055
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: P05120
Gene Symbols: SERPINB2
Immunogen: Recombinant protein corresponding to Human PAI2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
SERPINB2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SERPINB2
Gene Alias:
HsT1201; Monocyte Arg-serpin; ovalbumin; PAI; Pai2; PAI-2; Pai2a; Placental plasminogen activator inhibitor; Planh2; Plasminogen activator inhibitor 2; plasminogen activator inhibitor 2 type A; Plasminogen activator inhibitor 2, macrophage; plasminogen activator inhibitor, type II; plasminogen activator inhibitor, type II (arginine-serpin); serine (or cysteine) peptidase inhibitor, clade B, member 2; serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 2; serine (or cysteine) proteinase inhibitor, clade B, member 2; serpin B2; serpin family B member 2; serpin peptidase inhibitor, clade B (ovalbumin), member 2; SERPINB2; Urokinase inhibitor
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5055
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
P05120
Gene Symbols:
SERPINB2
Immunogen:
Recombinant protein corresponding to Human PAI2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TXNDC15
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TXNDC15
Gene Alias: 2310047H23Rik; C5orf14; disulfide isomerase; thioredoxin domain containing 15; thioredoxin domain-containing protein 15; TXNDC15; UNQ335; UNQ335/PRO534
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 79770
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q96J42
Gene Symbols: TXNDC15
Immunogen: Recombinant protein corresponding to Human TXNDC15
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TXNDC15
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TXNDC15
Gene Alias:
2310047H23Rik; C5orf14; disulfide isomerase; thioredoxin domain containing 15; thioredoxin domain-containing protein 15; TXNDC15; UNQ335; UNQ335/PRO534
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
79770
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q96J42
Gene Symbols:
TXNDC15
Immunogen:
Recombinant protein corresponding to Human TXNDC15
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: IL1RL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: IL1RL2
Gene Alias: AI481289; AW551444; IL-1 receptor-related protein 2; IL1RL2; IL1RRP2; IL-1Rrp2; IL1R-rp2; IL-36 receptor; IL-36R; interleukin 1 receptor like 2; interleukin 1 receptor-like 2; interleukin-1 receptor related protein 2; interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 8808
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.05 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q9HB29
Gene Symbols: IL1RL2
Immunogen: Recombinant protein corresponding to Human IL1RL2
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
IL1RL2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
IL1RL2
Gene Alias:
AI481289; AW551444; IL-1 receptor-related protein 2; IL1RL2; IL1RRP2; IL-1Rrp2; IL1R-rp2; IL-36 receptor; IL-36R; interleukin 1 receptor like 2; interleukin 1 receptor-like 2; interleukin-1 receptor related protein 2; interleukin-1 receptor-like 2; Interleukin-1 receptor-related protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
8808
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.05 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q9HB29
Gene Symbols:
IL1RL2
Immunogen:
Recombinant protein corresponding to Human IL1RL2
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: TMEM115
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TMEM115
Gene Alias: C78915; hypothetical protein LOC619264; LUCA11.2; PL6; PL6 protein; placental protein 6; Pp6; Protein PL6; Protein PL6 homolog; RGD1310540; testicular tissue protein Li 201; TMEM115; Transmembrane protein 115; wu:fc43c03; wu:fd18h12; zgc:114074; zgc:114074 protein
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11070
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry
Concentration: 0.1 mg/mL
Formulation: PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q12893
Gene Symbols: TMEM115
Immunogen: Recombinant protein corresponding to Human TMEM115
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
TMEM115
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TMEM115
Gene Alias:
C78915; hypothetical protein LOC619264; LUCA11.2; PL6; PL6 protein; placental protein 6; Pp6; Protein PL6; Protein PL6 homolog; RGD1310540; testicular tissue protein Li 201; TMEM115; Transmembrane protein 115; wu:fc43c03; wu:fd18h12; zgc:114074; zgc:114074 protein
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11070
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry
Concentration:
0.1 mg/mL
Formulation:
PBS with 40% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q12893
Gene Symbols:
TMEM115
Immunogen:
Recombinant protein corresponding to Human TMEM115
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG