PIPA572370

Phospho-Nephrin (Tyr1210) Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA572370-Each-of-1 In Stock ₹ 44,705.10

PIPA572370 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

Phospho-Nephrin (Tyr1210)

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Nphs1

Gene Alias

CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor

Host Species

Rabbit

Purification Method

Protein A

Regulatory Status

RUO

Gene ID (Entrez)

4868

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Dot Blot

Concentration

0.4 mg/mL

Formulation

PBS with 0.09% sodium azide

Gene Accession No.

O60500

Gene Symbols

Nphs1

Immunogen

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1210 of human Nephrin

Quantity

400 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Primary steroid resistant nephrotic syndrome (SRNS) is characterized by childhood onset of proteinuria and progression to end stage renal disease
  • Kidney podocytes and their slit diaphragms form the final barrier to urinary protein loss
  • Congenital nephrotic syndrome (CNS) is caused by mutations in NPHS1 (nephrin) or NPHS2
  • Nephrin, a recently identified protein is a member of a group of podocyte proteins that constitute major component of the slit diaphragm especially in the foot process
  • Nephrin, a cell adhesion molecule, may play a crucial role in maintaining the glomerular filtration barrier
  • Recent studies have suggested that mutations in the gene for Nephrin reportedly lead to congenital nephrosis
  • Three novel podocyte proteins, Podocin, Nephrin and alpha Actinin 4 have been identified in congenital and experimental models of proteinuria
  • The role of Nephrin in anti apoptotic activity in podocyte slit diaphragm is believed to be associated with vascular endothelial derived growth factors VEGF signaling
  • Nephrin seems to play a role in the development or function of the kidney glomerular filtration barrier and it may anchor the podocyte slit diaphragm to the actin cytoskeleton.

Compare Similar Items

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Thermo Scientific

PIPA572370

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Antigen:
Phospho-Nephrin (Tyr1210)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nphs1

Gene Alias:
CNF; Nephrin; nephrin 1; NephrinB; nephrosis 1 homolog, nephrin; nephrosis 1, congenital, Finnish type (nephrin); nephrosis 1, nephrin; NPHN; NPHS1; NPHS1 nephrin; NPHS1, nephrin; renal glomerulus-specific cell adhesion receptor

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
4868

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Dot Blot

Concentration:
0.4 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O60500

Gene Symbols:
Nphs1

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y1210 of human Nephrin

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA572371

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Antigen:
Phospho-JMJD2B (Ser566)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
KDM4B

Gene Alias:
4732474L06Rik; JHDM3B; JmjC domain-containing histone demethylation protein 3B; Jmjd2b; jumonji domain containing 2B; jumonji domain-containing protein 2B; KDM4B; KIAA0876; lysine (K)-specific demethylase 4B; lysine demethylase 4B; lysine-specific demethylase 4B; mKIAA0876; TDRD14B; tudor domain containing 14B

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
23030

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Dot Blot

Concentration:
0.35 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
O94953

Gene Symbols:
KDM4B

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S566 of human JMJD2B

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA572374

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Antigen:
Phospho-AMOT (Tyr599)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
AMOT

Gene Alias:
AMOT; Angiomotin; angiomotin p130 isoform; angiomotin p80 isoform; CAG-2; D0Kist1; KIAA1071; RGD1564027; si:dkey-13f9.6; Sii6; wu:fj21a07

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
154796

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Dot Blot

Concentration:
1.7 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q4VCS5

Gene Symbols:
AMOT

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y599 of human AMOT

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA572375

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Antigen:
Phospho-ULK2 (Ser323)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ULK2

Gene Alias:
A830085I22Rik; ATG1B; AU015340; EC:2.7.11.1; KIAA0623; mKIAA0623; serine/threonine-protein kinase ULK2; Serine/threonine-protein kinase Unc51.2; ULK2; unc-51 like autophagy activating kinase 2; unc-51 like kinase 2; Unc51.2; unc-51-like kinase 2

Host Species:
Rabbit

Purification Method:
Protein A

Regulatory Status:
RUO

Gene ID (Entrez):
9706

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Dot Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 0.09% sodium azide

Gene Accession No.:
Q8IYT8

Gene Symbols:
ULK2

Immunogen:
KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S323 of human ULK2

Quantity:
400 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG