PIPA576482
TIN2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA576482-Each-of-1 | In Stock | ₹ 47,614.14 |
PIPA576482 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 47,614.14
GST (18%): ₹ 8,570.545
Total Price: ₹ 56,184.685
Antigen
TIN2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Tinf2
Gene Alias
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
26277, 28113
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.
Q9BSI4, Q9QXG9
Gene Symbols
Tinf2
Immunogen
Recombinant protein of human TINF2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
- TRF1 is a negative regulator of telomere length maintenance
- Recently two proteins, tankyrase and Tin2, which bind to mammalian TRF1, have been identified
- Tankyrase is a protein with homology to ankyrins as well as to the catalytic domain of poly (adenosine diphosphate-ribose) polymerase (PARP)
- Tankyrase localizes to telomeres by binding to the telomeric repeat binding factor 1 (TRF1) through its ankyrin repeats
- Tankyrase exhibits PARP activity functioning as acceptors for adenosine diphosphate (ADP)-ribosylation
- Since ADP-ribosylation of TRF1 diminishes its ability to bind to telomeric DNA, this suggests that telomere function in human cells is regulated by poly (ADP)-ribosylation
- Both the cell cycle and TRF1 may regulate the subcellular localization of tankyrase
- The cDNA coding for TIN2 protein was isolated as interacting partner of TRF1 from a yeast two-hybrid cDNA library screening
- Tin2 localizes to telomeres and is essential for proper regulation of telomere length
- TIN2, like TRF1, is widely and constitutively expressed, suggesting that these proteins act together to counterbalance telomere elongation by telomerase
- However, endogenous TIN2, like endogenousTRF1, is not highly expressed, and therefore may be difficult to visualize by immunostaining in certain cell systems.
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Antigen: TIN2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Tinf2
Gene Alias: AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26277, 28113
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: Q9BSI4, Q9QXG9
Gene Symbols: Tinf2
Immunogen: Recombinant protein of human TINF2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
TIN2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Tinf2
Gene Alias:
AW552114; D14Wsu146e; DKCA3; TERF1 (TRF1)-interacting nuclear factor 2; TERF1 interacting nuclear factor 2; TERF1-interacting nuclear factor 2; tin; TIN2; Tin-2; TINF2; TRF1-interacting nuclear factor 2; TRF1-interacting nuclear protein 2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26277, 28113
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
Q9BSI4, Q9QXG9
Gene Symbols:
Tinf2
Immunogen:
Recombinant protein of human TINF2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: CHN1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Chn1
Gene Alias: 0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik; a2-chimaerin; A-chimaerin; AI413815; alpha1 chimaerin; alpha2 chimaerin; alpha3-chimerin; alpha-chimerin; ARHGAP2; chimaerin; chimaerin 1; chimerin (chimaerin) 1; chimerin 1; CHN; CHN1; DURS2; NC; N-chimaerin; N-chimerin; rho GTPase-activating protein 2; RHOGAP2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 108699, 1123, 84030
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P15882, P30337, Q91V57
Gene Symbols: Chn1
Immunogen: Recombinant protein of human CHN1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
CHN1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Chn1
Gene Alias:
0610007I19Rik; 0710001E19Rik; 1700112L09Rik; 2900046J01Rik; a2-chimaerin; A-chimaerin; AI413815; alpha1 chimaerin; alpha2 chimaerin; alpha3-chimerin; alpha-chimerin; ARHGAP2; chimaerin; chimaerin 1; chimerin (chimaerin) 1; chimerin 1; CHN; CHN1; DURS2; NC; N-chimaerin; N-chimerin; rho GTPase-activating protein 2; RHOGAP2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
108699, 1123, 84030
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P15882, P30337, Q91V57
Gene Symbols:
Chn1
Immunogen:
Recombinant protein of human CHN1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TTBK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TTBK2
Gene Alias: 2610507N02Rik; AI326283; B930008N24Rik; Bby; KIAA0847; mKIAA0847; Protein bartleby; SCA11; tau tubulin kinase 1; tau tubulin kinase 2; tau-tubulin kinase 2; Ttbk; Ttbk1; TTBK2; TTK
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 146057, 311349
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.: Q6IQ55
Gene Symbols: TTBK2
Immunogen: Recombinant protein of human TTBK2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TTBK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TTBK2
Gene Alias:
2610507N02Rik; AI326283; B930008N24Rik; Bby; KIAA0847; mKIAA0847; Protein bartleby; SCA11; tau tubulin kinase 1; tau tubulin kinase 2; tau-tubulin kinase 2; Ttbk; Ttbk1; TTBK2; TTK
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
146057, 311349
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.2
Gene Accession No.:
Q6IQ55
Gene Symbols:
TTBK2
Immunogen:
Recombinant protein of human TTBK2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: GluD1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GLUD1
Gene Alias: Ac2-281; AI118167; brain glutamate dehydrogenase; epididymis tissue sperm binding protein Li 18mP; GDH; GDH 1; GDH 2; Gdh1; GDH2; Gdh-X; Glud; GLUD1; GLUD1 protein; GLUD2; Gludeha; Gludl; GLUDP1; gluR delta-1 subunit; GluRdelta1; glutamate dehydrogenase; glutamate dehydrogenase (NAD(P)+); glutamate dehydrogenase 1; glutamate dehydrogenase 1, mitochondrial; glutamate dehydrogenase 2; glutamate dehydrogenase 2, mitochondrial; glutamate dehydrogenase pseudogene 1; glutamate ionotropic receptor delta type subunit 1; glutamate receptor delta-1 subunit; glutamate receptor ionotropic, delta-1; glutamate receptor, ionotropic, delta 1; Grid1; KIAA1220; Membrane protein 50; memory-related gene 2 protein; MP50; MRG-2; testicular secretory protein Li 14
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14661, 24399, 2746
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.: P00367, P10860, P26443
Gene Symbols: GLUD1
Immunogen: Recombinant protein of human Glutamate Dehydrogenase.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GluD1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GLUD1
Gene Alias:
Ac2-281; AI118167; brain glutamate dehydrogenase; epididymis tissue sperm binding protein Li 18mP; GDH; GDH 1; GDH 2; Gdh1; GDH2; Gdh-X; Glud; GLUD1; GLUD1 protein; GLUD2; Gludeha; Gludl; GLUDP1; gluR delta-1 subunit; GluRdelta1; glutamate dehydrogenase; glutamate dehydrogenase (NAD(P)+); glutamate dehydrogenase 1; glutamate dehydrogenase 1, mitochondrial; glutamate dehydrogenase 2; glutamate dehydrogenase 2, mitochondrial; glutamate dehydrogenase pseudogene 1; glutamate ionotropic receptor delta type subunit 1; glutamate receptor delta-1 subunit; glutamate receptor ionotropic, delta-1; glutamate receptor, ionotropic, delta 1; Grid1; KIAA1220; Membrane protein 50; memory-related gene 2 protein; MP50; MRG-2; testicular secretory protein Li 14
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14661, 24399, 2746
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene Accession No.:
P00367, P10860, P26443
Gene Symbols:
GLUD1
Immunogen:
Recombinant protein of human Glutamate Dehydrogenase.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG