PIPA585228
APE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585228-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA585228 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
APE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APEX1
Gene Alias
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
11792, 328
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.
P27695, P28352
Gene Symbols
APEX1
Immunogen
Recombinant protein encompassing a sequence within the center region of human APE1.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Predicted reactivity: Mouse (97%), Rat (96%), Dog (98%), Pig (97%), Rhesus Monkey (98%), Chimpanzee (99%), Bovine (97%)
- Positive Control: A431, mouse brain, HeLa
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
- APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
- The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
- APE is differentially expressed during development and in different tissues
- This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
- Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
- Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some malignant tissue relative to normal tissue
- Decreases in APE expression have been associated with the induction of cellular apoptosis.
Compare Similar Items
Show Difference
Antigen: APE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APEX1
Gene Alias: AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11792, 328
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: P27695, P28352
Gene Symbols: APEX1
Immunogen: Recombinant protein encompassing a sequence within the center region of human APE1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
APE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APEX1
Gene Alias:
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11792, 328
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
P27695, P28352
Gene Symbols:
APEX1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human APE1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: NEGR1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: NEGR1
Gene Alias: 5330422G01Rik, a kindred of IgLON, DMML2433, IgLON family member 4, IGLON4, Kiaa3001, KILON, kilon protein, kindred of IgLON, NEGR1, Neuronal growth regulator 1, neurotractin, Ntra, UNQ2433, UNQ2433/PRO4993
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 257194, 320840
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin)
Concentration: 0.3 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: Q7Z3B1, Q80Z24
Gene Symbols: NEGR1
Immunogen: Recombinant protein encompassing a sequence within the center region of human NEGR1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
NEGR1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
NEGR1
Gene Alias:
5330422G01Rik, a kindred of IgLON, DMML2433, IgLON family member 4, IGLON4, Kiaa3001, KILON, kilon protein, kindred of IgLON, NEGR1, Neuronal growth regulator 1, neurotractin, Ntra, UNQ2433, UNQ2433/PRO4993
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
257194, 320840
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin)
Concentration:
0.3 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
Q7Z3B1, Q80Z24
Gene Symbols:
NEGR1
Immunogen:
Recombinant protein encompassing a sequence within the center region of human NEGR1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: VCPIP1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: VCPIP1
Gene Alias: 4932442A08; 5730421J18Rik; 5730538E15Rik; Deubiquitinating protein VCIP135; DUBA3; KIAA1850; mKIAA1850; valosin containing protein (p97)/p47 complex interacting protein 1; valosin containing protein interacting protein 1; valosin-containing protein (p97)/p47 complex-interacting protein 135; valosin-containing protein (p97)/p47 complex-interacting protein p135; valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCIP135; VCP(p97)/p47-interacting protein; VCP/p47 complex-interacting 135-kDa protein; VCPIP1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 70675, 80124
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: 0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.: Q8CDG3, Q96JH7
Gene Symbols: VCPIP1
Immunogen: Recombinant protein encompassing a sequence within the C-terminus region of human VCPIP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
VCPIP1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
VCPIP1
Gene Alias:
4932442A08; 5730421J18Rik; 5730538E15Rik; Deubiquitinating protein VCIP135; DUBA3; KIAA1850; mKIAA1850; valosin containing protein (p97)/p47 complex interacting protein 1; valosin containing protein interacting protein 1; valosin-containing protein (p97)/p47 complex-interacting protein 135; valosin-containing protein (p97)/p47 complex-interacting protein p135; valosin-containing protein p97/p47 complex-interacting protein 1; Valosin-containing protein p97/p47 complex-interacting protein p135; VCIP135; VCP(p97)/p47-interacting protein; VCP/p47 complex-interacting 135-kDa protein; VCPIP1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
70675, 80124
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
0.1M tris glycine with 10% glycerol and 0.01% thimerosal; pH 7
Gene Accession No.:
Q8CDG3, Q96JH7
Gene Symbols:
VCPIP1
Immunogen:
Recombinant protein encompassing a sequence within the C-terminus region of human VCPIP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TrkC
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ntrk3
Gene Alias: AW125844, ETS related protein-neurotrophic receptor tyrosine kinase fusion protein, ETV6-NTRK3 fusion, gp145(trkC), GP145-TrkC, neural receptor protein-tyrosine kinase (trkC), neurotrophic receptor tyrosine kinase 3, Neurotrophic tyrosine kinase receptor type 3, neurotrophic tyrosine kinase, receptor, type 3, neurotrophin-3, NT-3 growth factor receptor, NTRK3, Ntrk3_tv3, TrkC, trk-C, trkC tyrosine kinase, tyrosine kinase receptor, tyrosine kinase receptor C
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18213, 29613, 4916
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.: Q03351, Q16288, Q6VNS1
Gene Symbols: Ntrk3
Immunogen: Recombinant protein encompassing a sequence within the center region of human TrkC.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TrkC
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ntrk3
Gene Alias:
AW125844, ETS related protein-neurotrophic receptor tyrosine kinase fusion protein, ETV6-NTRK3 fusion, gp145(trkC), GP145-TrkC, neural receptor protein-tyrosine kinase (trkC), neurotrophic receptor tyrosine kinase 3, Neurotrophic tyrosine kinase receptor type 3, neurotrophic tyrosine kinase, receptor, type 3, neurotrophin-3, NT-3 growth factor receptor, NTRK3, Ntrk3_tv3, TrkC, trk-C, trkC tyrosine kinase, tyrosine kinase receptor, tyrosine kinase receptor C
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18213, 29613, 4916
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 20% glycerol and 0.01% thimerosal, pH 7
Gene Accession No.:
Q03351, Q16288, Q6VNS1
Gene Symbols:
Ntrk3
Immunogen:
Recombinant protein encompassing a sequence within the center region of human TrkC.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG