PIPA588088
APE1 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588088-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588088 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
APE1
Classification
Polyclonal
Conjugate
Unconjugated
Gene
APEX1
Gene Alias
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
328
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunocytochemistry, Western Blot, Western Blot
Concentration
1.13 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
P27695
Gene Symbols
APEX1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: MPKRGKKGAV AEDGDELRTE PEAKKSKTAA KKNDKEAAGE GPALYEDPPD QKTSPSGKPA TLKICSWNVD GLRAWIKKKG LDWVKEEAPD ILCLQETKCS ENKLPAELQE LPGLSHQYWS APSDKEGYSG VGLLSRQCPL KVSYGIGDEE HDQEGRVIVA EFDSFVLVTA YVPNAGRGLV RLEYRQRWDE AFRKFLKGLA SRKPLVLCGD LNVAHEEIDL RNPKGNKKNA GFTPQERQGF GELLQAVPLA DSFRHLYPNT PYAYTFWTYM MNARSKNVGW RLDYFLLSHS LLPALCDSKI RSKALGSDHC PITLYLAL; Positive Samples: HeLa, HepG2; Cellular Location: Cytoplasm, Endoplasmic reticulum, Mitochondrion, Nucleus, Nucleus speckle, nucleolus Mammalian apurinic/apyrimidinic endonuclease (APE/ref-1) is a multifunctional, bipartite enzyme that plays an important role in numerous, cellular functions
- APE is responsible for repairing abasic sites in DNA and in regulating the redox state of other proteins that play roles in oxidative signaling, transcription factor regulation (Fos, Jun, NF-kB, Myb, HIF-1 alpha, CREB, Pax), cell cycle control (p53), and apoptosis
- The most common form of DNA damage is the creation of abasic sites which are brought about through spontaneous loss or oxidative DNA damage, through chemically initiated hydrolysis (chemotherapy), ionizing radiation, UV irradiation, oxidizing agents, and removal of modified bases by DNA glycosylases
- APE is differentially expressed during development and in different tissues
- This protein has diverse subcellular localization patterns which support the possibility of its interaction with numerous, other cellular proteins in addition to DNA repair within the nucleus
- Regulation of APE by phosphorylation is mediated, at least in part, by casein kinase II
- Increases in APE message and protein levels are observed upon the reintroduction of oxygen to hypoxic cells, and in some malignant tissue relative to normal tissue
- Decreases in APE expression have been associated with the induction of cellular apoptosis.
Compare Similar Items
Show Difference
Antigen: APE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APEX1
Gene Alias: AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 328
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 1.13 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P27695
Gene Symbols: APEX1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
APE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APEX1
Gene Alias:
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
328
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
1.13 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P27695
Gene Symbols:
APEX1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-318 of human APEX1/APE1 (NP_5423801)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PI3K p85 alpha
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PIK3R1
Gene Alias: AGM7, GRB1, IMD36, p50alpha, p55alpha, p55-GAMMA, p55PIK, p85, p85alpha, p85-ALPHA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphatidylinositol 3-kinase-associated p-85 alpha, Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50), Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphoinositide-3-kinase regulatory subunit, phosphoinositide-3-kinase regulatory subunit 1, phosphoinositide-3-kinase regulatory subunit alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha), phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), PI3K, PI3K regulatory subunit alpha, PI3K regulatory subunit gamma, PI3KA, PI3-kinase p85 subunit alpha, PI3-kinase p85-subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, PI3-kinase subunit p85-alpha, Pik3r1, polypeptide 1 p85 alpha, ptdIns-3-kinase p85-alpha, ptdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-al, ptdIns-3-kinase regulatory subunit p85-alpha, RP4-533D7.2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18708, 25513, 5295
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.04 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P26450, P27986, Q63787
Gene Symbols: PIK3R1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human PI3 Kinase p85 alpha (NP_8526641)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
PI3K p85 alpha
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PIK3R1
Gene Alias:
AGM7, GRB1, IMD36, p50alpha, p55alpha, p55-GAMMA, p55PIK, p85, p85alpha, p85-ALPHA, phosphatidylinositol 3-kinase, phosphatidylinositol 3-kinase 55 kDa regulatory subunit gamma, phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha, Phosphatidylinositol 3-kinase regulatory subunit alpha, phosphatidylinositol 3-kinase regulatory subunit gamma, phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphatidylinositol 3-kinase-associated p-85 alpha, Phosphoinositide 3-kinase p85 (other splicing variants: p55 and p50), Phosphoinositide 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), phosphoinositide-3-kinase regulatory subunit, phosphoinositide-3-kinase regulatory subunit 1, phosphoinositide-3-kinase regulatory subunit alpha, phosphoinositide-3-kinase, regulatory subunit 1 (alpha), phosphoinositide-3-kinase, regulatory subunit 1 (p85 alpha), phosphoinositide-3-kinase, regulatory subunit, polypeptide 1 (p85 alpha), PI3K, PI3K regulatory subunit alpha, PI3K regulatory subunit gamma, PI3KA, PI3-kinase p85 subunit alpha, PI3-kinase p85-subunit alpha, PI3-kinase regulatory subunit alpha, PI3-kinase regulatory subunit gamma, PI3-kinase subunit p55-gamma, PI3-kinase subunit p85-alpha, Pik3r1, polypeptide 1 p85 alpha, ptdIns-3-kinase p85-alpha, ptdIns-3-kinase regulatory subunit alpha, PtdIns-3-kinase regulatory subunit p85-al, ptdIns-3-kinase regulatory subunit p85-alpha, RP4-533D7.2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18708, 25513, 5295
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.04 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P26450, P27986, Q63787
Gene Symbols:
PIK3R1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-380 of human PI3 Kinase p85 alpha (NP_8526641)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: POLR2A
Classification: Polyclonal
Conjugate: Unconjugated
Gene: POLR2A
Gene Alias: 220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 20020, 363633, 5430
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.83 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P08775, P24928
Gene Symbols: POLR2A
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 1-260 of human POLR2A (NP_0009281)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
POLR2A
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
POLR2A
Gene Alias:
220kDa, DNA polymerase epsilon catalytic subunit, DNA polymerase epsilon catalytic subunit A, DNA polymerase II subunit A, DNA-directeced RNA polymerase II polypeptide A, DNA-directed RNA polymerase II largest subunit, RNA polymerase II 220 kd subunit, DNA-directed RNA polymerase II subunit A, DNA-directed RNA polymerase II subunit RPB1, DNA-directed RNA polymerase III largest subunit, DUN2, EC 2.7.7.6, hRPB220, hsRPB1, MGC75453, N0825, Pol II S2p, POL2, POLR2, Polr2a, POLRA, Polymerase (RNA II (DNA directed), large polypeptide, polymerase (RNA) II (DNA directed) polypeptide A, polymerase (RNA) II (DNA directed) polypeptide A (220kD), polymerase (RNA) II (DNA directed) polypeptide A, 220kDa, polymerase (RNA) II subunit A, POLYMERASE II, RNA, RNA POL2, RNA polymerase II 1, RNA polymerase II subunit A, RNA polymerase II subunit B1, RNA-directed RNA polymerase II subunit RPB1, RP02, RPB1, RPB220, RPBh1, Rpii215, RpIILS, RPO2, RPO21, Rpo2-1, RPOL2, SUA8, YNL262W
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
20020, 363633, 5430
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
ChIP Assay, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.83 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P08775, P24928
Gene Symbols:
POLR2A
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-260 of human POLR2A (NP_0009281)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Glucagon
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Gcg
Gene Alias: GCG, Glicentin, Glicentin-related polypeptide, GLP1, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP1/2, GLP2, GLP-2, Glu, glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, glucagon-like peptide-1, GRPP, IL12p35, IL12P40, Incretin hormone, OXM, OXY, Oxyntomodulin, porcine proglucagon, PPG, preproglucagon, proglucagon
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 14526, 24952, 2641
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P01275, P06883, P55095
Gene Symbols: Gcg
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_0020451)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Glucagon
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Gcg
Gene Alias:
GCG, Glicentin, Glicentin-related polypeptide, GLP1, GLP-1, GLP-1(7-36), GLP-1(7-37), GLP1/2, GLP2, GLP-2, Glu, glucagon, Glucagon-like peptide 1, Glucagon-like peptide 1(7-36), Glucagon-like peptide 1(7-37), Glucagon-like peptide 2, glucagon-like peptide-1, GRPP, IL12p35, IL12P40, Incretin hormone, OXM, OXY, Oxyntomodulin, porcine proglucagon, PPG, preproglucagon, proglucagon
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
14526, 24952, 2641
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P01275, P06883, P55095
Gene Symbols:
Gcg
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_0020451)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG