PIPA585393

IDO Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585393-Each-of-1 In Stock ₹ 45,047.34

PIPA585393 - Each of 1

₹ 45,047.34

In Stock

Quantity

1

Base Price: ₹ 45,047.34

GST (18%): ₹ 8,108.521

Total Price: ₹ 53,155.861

Antigen

IDO

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Ido1

Gene Alias

EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

3620

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Frozen), Western Blot

Concentration

1 mg/mL

Formulation

0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.

P14902

Gene Symbols

Ido1

Immunogen

Recombinant protein encompassing a sequence within the center region of human IDO1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Keep as concentrated solution
  • Predicted reactivity: Rhesus Monkey (97%)
  • Positive Control: A549 (starvation for 24 hr, and 100 ng/mL IFN-gamma treatment for 48 hr), IDO1-transfected 293T
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • IDO1 is an intracellular heme-containing enzyme that catalyzes the oxidative cleavage of the indole ring of several important regulatory molecules like tryptophan, serotonin, and melatonin
  • By doing this, IDO1 initiates the production of biologically active metabolites, commonly referred to as kynurenines
  • IDO1 is widely expressed in a variety of human tissues as well as in macrophages and dendritic cells (DCs)
  • In inflammation, interferons (IFNs) act on specific receptors to trigger IDO1 induction
  • The production of IFN-gamma and induction of IDO1 represent important antimicrobial mechanisms
  • Degradation and depletion of tryptophan by IDO1 inhibits the growth of viruses, bacteria and parasites
  • Furthermore, IDO1 plays a complex and crucial role in immunoregulation during infection, pregnancy, autoimmunity, transplantation, and neoplasia.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585393

--


Antigen:
IDO

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ido1

Gene Alias:
EC 1.13.11.52; IDO; IDO1; IDO-1; INDO; indolamine 2,3 dioxygenase; indole 2,3-dioxygenase; indoleamine; indoleamine 2,3-dioxygenase 1; indoleamine 23-dioxygenase; Indoleamine-2; indoleamine-pyrrole 2,3 dioxygenase; indoleamine-pyrrole 2,3-dioxygenase

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3620

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Frozen), Western Blot

Concentration:
1 mg/mL

Formulation:
0.1M tris glycine with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P14902

Gene Symbols:
Ido1

Immunogen:
Recombinant protein encompassing a sequence within the center region of human IDO1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA585395

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Antigen:
RXRA

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Rxra

Gene Alias:
9530071D11Rik; Nr2b1; Nuclear receptor subfamily 2 group B member 1; retinoic acid receptor RXR-alpha; retinoid X nuclear receptor alpha; retinoid X receptor; retinoid X receptor alpha; retinoid X receptor, alpha; rxr alpha; RXR alpha 1; Rxra; RXRalpha1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
25271, 6256

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunoprecipitation, Western Blot

Concentration:
0.98 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
P19793, Q05343

Gene Symbols:
Rxra

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Retinoid X Receptor alpha.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA585396

--


Antigen:
SNAP25

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Snap25

Gene Alias:
ALMS1; bA416N4.2; Bdr; blind drunk; CG17676; CG17884; CG40452; CMS18; dJ1068F16.2; Dmel CG40452; Dmel_CG40452; etID17571.20; etID69167.20; fj42b02; fj45g04; fj48c02; FLJ23079; GENA70; HGNC:11132; resistance to inhibitors of cholinesterase 4 homolog; RIC4; RIC-4; SEC9; si:dkeyp-8f4.6; Snap; SNAP 25; snap25; SNAP-25; snap25.1; SNAP-25.1; snap25a; SNAP-25A; SNAP-25B; snp25; sp; SUP; super protein; synaptosomal associated protein-25; synaptosomal-associated 25 kDa protein; Synaptosomal-associated protein 25; synaptosomal-associated protein 25-A; synaptosomal-associated protein, 25 kDa; synaptosomal-associated protein, 25a; synaptosomal-associated protein, 25kDa; synaptosome associated protein 25; synaptosome associated protein 25a; synaptosome associated protein 25kDa; synaptosome-associated protein 25.1; synaptosome-associated protein 25a; wu:fj42b02; wu:fj45g04; wu:fj48c02

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
20614, 25012, 6616

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Western Blot

Concentration:
0.27 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P60879, P60880, P60881

Gene Symbols:
Snap25

Immunogen:
Recombinant protein encompassing a sequence within the center region of human SNAP25.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585397

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Antigen:
FZD6

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
FZD6

Gene Alias:
frizzled 6; frizzled 6, seven transmembrane spanning receptor; frizzled class receptor 6; frizzled family receptor 6; frizzled homolog 6; frizzled homolog 6 (Drosophila); Frizzled6; frizzled-6; FZ6; Fz-6; Fzd6; FZD-6; HFZ6; mFz6; NDNC10; seven transmembrane helix receptor

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 20% glycerol and 0.01% thimerosal; pH 7

Gene Accession No.:
O60353

Gene Symbols:
FZD6

Immunogen:
Recombinant protein encompassing a sequence within the center region of human Frizzled 6.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG