PIPA585712
ATM Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA585712-Each-of-1 | In Stock | ₹ 45,218.46 |
PIPA585712 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 45,218.46
GST (18%): ₹ 8,139.323
Total Price: ₹ 53,357.783
Antigen
ATM
Classification
Polyclonal
Conjugate
Unconjugated
Gene
ATM
Gene Alias
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
472
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Western Blot, Western Blot
Concentration
1.14 mg/mL
Formulation
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.
Q13315
Gene Symbols
ATM
Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ATM.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Keep as concentrated solution
- Positive Control: HeLa, H1299
- Store product as a concentrated solution
- Centrifuge briefly prior to opening the vial
- Ataxia-telangiectasia Mutated (ATM) is a protein that belongs to the PI3/PI4 kinase family
- Ataxia-telangiectasia is a rare autosomal recessive disorder characterized by progressive neurologic degeneration, immunologic deficiency, and an increased risk of lymphoid cancer
- The ATM gene codes for a protein belonging to the phosphoinositide 3-kinase (PI3K) superfamily
- ATM phosphorylates proteins instead of lipid and has many downstream targets that act as cell-cycle regulators including: P53, Mdm2, BRCA1, and SMC1
- The ATM protein is responsible for repairing double-stranded DNA breaks that occur because of ionizing radiation and other mutagens
- The ATM’s C-terminal region has extensive homology to the catalytic domains of phosphatidylinositol 3-kinases (PI3 kinases)
- Studies have shown that ATM becomes autophosphorylated and upregulated by exposure to ionizing radiation
- AT cells are hypersensitive to ionizing radiation, impaired in mediating the inhibition of DNA synthesis and display delays in p53 induction
- Further, DNA damage caused by ionizing irradiation activates ATM-kinase, leading to a cascade of kinase reactions that regulate cell cycle, apoptosis, and DNA damage repair
- Studies have linked ATM to apoptosis along with Nbs1 and Chk2 in the E2F1 pathway.
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Antigen: ATM
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ATM
Gene Alias: AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 472
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Western Blot, Western Blot
Concentration: 1.14 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: Q13315
Gene Symbols: ATM
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ATM.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
ATM
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ATM
Gene Alias:
AI256621, AT mutated, A-T mutated, A-T mutated homolog, AT mutated protein, AT1, ATA, Ataxia t, Ataxia telangiectasia gene mutated in human beings, ataxia telangiectasia mutated, Ataxia telangiectasia mutated homolog, ATC, ATD, ATDC, ATE, Atm, ATM (phospho S1981), ATM (pS1981), ATM (pSer1981), ATM phospho S1981, ATM phospho Ser1981, ATM serine/threonine kinase, C030026E19Rik, DKFZp781A0353, EC 2.7.1.37, MGC74674, phospho ATM, phospho S1981 ATM, serine-protein kinase ATM, TEL1, TEL1, telomere maintenance 1, homolog, TELO1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
472
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot, Western Blot
Concentration:
1.14 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
Q13315
Gene Symbols:
ATM
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ATM.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: Phospho-RAD17 (Ser656)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Rad17
Gene Alias: CCYC, cell cycle checkpoint protein (RAD17), cell cycle checkpoint protein RAD17, DNA damage checkpoint control protein RAD17, DNA repair exonuclease RAD17, FLJ41520, hRad17, MmRad24, R24L, RAD1 homolog, RAD17, RAD17 (Ser647), RAD17 checkpoint clamp loader component, RAD17 homolog, RAD17 homolog (S. pombe), Rad17 like protein, Rad17-like protein, Rad17p, RAD17SP, RAD24, RF-C activator 1 homolog, RF-C/activator 1 homolog, YOR368W
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5884
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration: 2.25 mg/mL
Formulation: PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: O75943
Gene Symbols: Rad17
Immunogen: Carrier-protein conjugated synthetic peptide corresponding to residues around human Rad17 (phospho Ser656).
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
Phospho-RAD17 (Ser656)
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Rad17
Gene Alias:
CCYC, cell cycle checkpoint protein (RAD17), cell cycle checkpoint protein RAD17, DNA damage checkpoint control protein RAD17, DNA repair exonuclease RAD17, FLJ41520, hRad17, MmRad24, R24L, RAD1 homolog, RAD17, RAD17 (Ser647), RAD17 checkpoint clamp loader component, RAD17 homolog, RAD17 homolog (S. pombe), Rad17 like protein, Rad17-like protein, Rad17p, RAD17SP, RAD24, RF-C activator 1 homolog, RF-C/activator 1 homolog, YOR368W
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5884
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Western Blot
Concentration:
2.25 mg/mL
Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
O75943
Gene Symbols:
Rad17
Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human Rad17 (phospho Ser656).
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: CRY1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CRY1
Gene Alias: AU020726, AU021000, Cry1, cryptochrome 1 (photolyase-like), cryptochrome circadian clock 1, cryptochrome-1, PHLL1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1407
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1.19 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: Q16526
Gene Symbols: CRY1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRY1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
CRY1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CRY1
Gene Alias:
AU020726, AU021000, Cry1, cryptochrome 1 (photolyase-like), cryptochrome circadian clock 1, cryptochrome-1, PHLL1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
1407
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1.19 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
Q16526
Gene Symbols:
CRY1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the N-terminus region of human CRY1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG
Antigen: PTGER1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ptger1
Gene Alias: 42kDa, EP1, EP1 prostanoid receptor, PGE receptor EP1 subtype, PGE receptor, EP1 subtype, PGE2 receptor EP1 subtype, prostaglandin E receptor 1, prostaglandin E receptor 1 (subtype EP1), prostaglandin E receptor 1 (subtype EP1), 42kD, prostaglandin E receptor 1 (subtype EP1), 42kDa, prostaglandin E receptor 1, subtype EP1, prostaglandin E receptor EP1 subtype, prostaglandin E2 receptor EP1 subtype, Prostanoid EP1 receptor, PTGER1, Ptgerep1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 5731
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Western Blot
Concentration: 1.03 mg/mL
Formulation: PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.: P34995
Gene Symbols: Ptger1
Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Prostaglandin E Receptor EP1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen:
PTGER1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ptger1
Gene Alias:
42kDa, EP1, EP1 prostanoid receptor, PGE receptor EP1 subtype, PGE receptor, EP1 subtype, PGE2 receptor EP1 subtype, prostaglandin E receptor 1, prostaglandin E receptor 1 (subtype EP1), prostaglandin E receptor 1 (subtype EP1), 42kD, prostaglandin E receptor 1 (subtype EP1), 42kDa, prostaglandin E receptor 1, subtype EP1, prostaglandin E receptor EP1 subtype, prostaglandin E2 receptor EP1 subtype, Prostanoid EP1 receptor, PTGER1, Ptgerep1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
5731
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Western Blot
Concentration:
1.03 mg/mL
Formulation:
PBS with 20% glycerol and 0.025% ProClin 300, pH 7
Gene Accession No.:
P34995
Gene Symbols:
Ptger1
Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human Prostaglandin E Receptor EP1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human
Product Type:
Antibody
Isotype:
IgG