PIPA585733

ULK1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA585733-Each-of-1 In Stock ₹ 44,191.74

PIPA585733 - Each of 1

₹ 44,191.74

In Stock

Quantity

1

Base Price: ₹ 44,191.74

GST (18%): ₹ 7,954.513

Total Price: ₹ 52,146.253

Antigen

ULK1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ULK1

Gene Alias

APG1, ATG 1, ATG1, ATG1 autophagy related 1 homolog, ATG1A, AU041434, Autophagy-related protein 1 homolog, C. elegans, EC:2.7.11.1, FLJ38455, hATG1, KIAA0722, mKIAA0722, Serine/threonine-protein kinase ULK1, serine/threonine-protein kinase Unc51.1, ULK 1, Ulk1, UNC 51, UNC51, unc-51 like autophagy activating kinase 1, unc-51 like kinase 1, Unc51.1, unc-51-like kinase 1

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

8408

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

0.24 mg/mL

Formulation

PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.

O75385

Gene Symbols

ULK1

Immunogen

Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ULK1.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

Related Products

Img

Thermo Scientific

PIPA585237

--

Img

Thermo Scientific

PIPA585718

--

Img

Thermo Scientific

PIPA585243

--

Img

Thermo Scientific

PIPA585714

--

Img

Thermo Scientific

PIPA585507

--

Img

Thermo Scientific

PIPA585313

--

Img

Thermo Scientific

PIPA585712

--

Img

Thermo Scientific

PIPA585467

--

Description

  • Keep as concentrated solution
  • Predicted reactivity: Mouse (100%)
  • Positive Control: Jurkat, IMR32, SK-N-AS
  • Store product as a concentrated solution
  • Centrifuge briefly prior to opening the vial
  • ULK1 is a serine/threonine protein kinase that plays critical role during initial stages of autophagy which is a vital response to nutrient starvation
  • The conserved C-terminal domain (CTD) of ULK1 controls the regulatory function and localization of the protein
  • Knockdown of ULK1 inhibits the autophagic response as well as inhibiting rapamycin-induced autophagy consistent with a role downstream of mTOR
  • ULK1 forms a complex with FIP200 and ATG13 and this complex is essential for starvation-induced autophagy
  • Both FIP200 and ATG13 are critical for correct localization of ULK1 to the pre-autophagosome and stability of ULK1 protein
  • ULK1 is phosphorylated by the mTOR pathway in a nutrient starvation-regulated manner.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA585733

--


Antigen:
ULK1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ULK1

Gene Alias:
APG1, ATG 1, ATG1, ATG1 autophagy related 1 homolog, ATG1A, AU041434, Autophagy-related protein 1 homolog, C. elegans, EC:2.7.11.1, FLJ38455, hATG1, KIAA0722, mKIAA0722, Serine/threonine-protein kinase ULK1, serine/threonine-protein kinase Unc51.1, ULK 1, Ulk1, UNC 51, UNC51, unc-51 like autophagy activating kinase 1, unc-51 like kinase 1, Unc51.1, unc-51-like kinase 1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
8408

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.24 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
O75385

Gene Symbols:
ULK1

Immunogen:
Carrier-protein conjugated synthetic peptide encompassing a sequence within the center region of human ULK1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585735

--


Antigen:
Phospho-JAK2 (Tyr1007, Tyr1008)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
JAK2

Gene Alias:
EC 2.7.10.2, Fd17, JAK 2, JAK2, JAK-2, Janus kinase 2, Janus kinase 2 (a protein tyrosine kinase), JTK 10, JTK10, kinase Jak2, THCYT3, Tyrosine-protein kinase JAK2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
3717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.25 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
O60674

Gene Symbols:
JAK2

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human JAK2 (phospho Tyr1007/1008).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585736

--


Antigen:
Phospho-mTOR (Ser2448)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MTOR

Gene Alias:
2610315D21Rik, AI327068, angiopoietin-like factor CDT6, FK506 binding protein 12-rapamycin associated protein 1, FK506 binding protein 12-rapamycin associated protein 2, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, FKBP12-rapamycin complex-associated protein 1, FKBP-rapamycin associated protein, FKBP-rapamycin associated protein (FRAP), FKBP-rapamycin-associated protein FRAP, flat, FRAP, FRAP1, FRAP2, Mammalian target of rapamycin, mechanistic target of rapamycin, mechanistic target of rapamycin (serine/threonine kinase), mechanistic target of rapamycin kinase, Mtor, m-TOR, mTORC1, Raft1, Rapamycin and FKBP12 target 1, rapamycin and FKBP12 target-1 protein, rapamycin associated protein FRAP2, rapamycin target protein 1, RAPT1, serine/threonine-protein kinase mTOR, SKS

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
2475, 56717

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.1 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300, pH 7

Gene Accession No.:
P42345, Q9JLN9

Gene Symbols:
MTOR

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human mTOR (phospho Ser2448).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA585740

--


Antigen:
Phospho-Phospholamban (Ser16)

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PLN

Gene Alias:
cardiac CMH18; Cardiac phospholamban; CMD1P; CMH18; phospholamban; Plb; Plm; PLN; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18821, 5350

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
0.97 mg/mL

Formulation:
PBS with 1% BSA, 20% glycerol and 0.025% ProClin 300; pH 7

Gene Accession No.:
P26678, P61014

Gene Symbols:
PLN

Immunogen:
Carrier-protein conjugated synthetic peptide corresponding to residues around human Phospholamban (phospho Ser16).

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG