PIPA586103

LC3B Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586103-Each-of-1 In Stock ₹ 53,646.12

PIPA586103 - Each of 1

₹ 53,646.12

In Stock

Quantity

1

Base Price: ₹ 53,646.12

GST (18%): ₹ 9,656.302

Total Price: ₹ 63,302.422

Antigen

LC3B

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MAP1LC3B2

Gene Alias

1010001C15Rik, Atg8, ATG8E, ATG8F, ATG8G, Autophagy-related protein LC3 B, autophagy-related ubiquitin-like modifier LC3 B, LC3, LC3 beta, LC3A, LC3B, light chain 3, MAP1 light chain 3-like protein 2, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, Map1alc3, MAP1BLC3, MAP1LC3, MAP1LC3A, MAP1LC3B, MAP1LC3B2, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta 2, microtubule-associated protein 1 light chain 3, microtubule-associated protein 1 light chain 3 beta, microtubule-associated protein 1 light chain 3 beta 2, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3 beta 2, Microtubule-associated proteins 1A/1B light chain 3B, Microtubule-associated proteins 1A/1B light chain 3B-like, Microtubule-associated proteins 1A/1B light chain 3B-like protein, Mpl3, RP11-346K17.1, wu:fb60g11, zbs559, zgc:56434

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

100359928, 643246, 64862, 67443, 81631

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

A6NCE7, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols

MAP1LC3B, MAP1LC3B2

Immunogen

Recombinant MAP1LC3B protein, corresponding to amino acids 1-125 of Human MAP1LC3B.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • LC3B (Autophagy Marker Light Chain 3B, MAP1A/MAP1B LC3 B) in humans, is encoded by the gene MAP1LC3B (Microtubule-associated proteins 1A/1B light chain 3B)
  • LC3B is associated with microtubule assembly and important is in neurogenesis
  • Recent studies indicate that LC3B plays a vital role in autophagy, a process that involves the bulk degradation of cytoplasmic component
  • Three human LC3 isoforms undergo post-translational modifications during autophagy
  • Macroautophagy is the major inducible pathway for the general turnover of cytoplasmic constituents in eukaryotic cells, it is also responsible for the degradation of active cytoplasmic enzymes and organelles during nutrient starvation
  • Macroautophagy involves the formation of double-membrane bound autophagosomes which enclose the cytoplasmic constituent targeted for degradation in a membrane bound structure, which then fuse with the lysosome (or vacuole) releasing a single-membrane bound autophagic bodies which are then degraded within the lysosome (or vacuole)
  • LC3B is a microtubule-associated protein that mediate the physical interactions between microtubules and components of the cytoskeleton
  • LC3B may play a role in processes involving cancer, aging, metabolic and neurodegenerative disorders and cardiovascular/pulmonary diseases.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA586103

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Antigen:
LC3B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP1LC3B2

Gene Alias:
1010001C15Rik, Atg8, ATG8E, ATG8F, ATG8G, Autophagy-related protein LC3 B, autophagy-related ubiquitin-like modifier LC3 B, LC3, LC3 beta, LC3A, LC3B, light chain 3, MAP1 light chain 3-like protein 2, MAP1A/1B light chain 3 B, MAP1A/1BLC3, MAP1A/MAP1B LC3 A, MAP1A/MAP1B LC3 B, MAP1A/MAP1B light chain 3 B, Map1alc3, MAP1BLC3, MAP1LC3, MAP1LC3A, MAP1LC3B, MAP1LC3B2, MAP1LC3B-a, microtubule associated protein 1 light chain 3 beta, microtubule associated protein 1 light chain 3 beta 2, microtubule-associated protein 1 light chain 3, microtubule-associated protein 1 light chain 3 beta, microtubule-associated protein 1 light chain 3 beta 2, microtubule-associated proteins 1A/1B light chain 3, microtubule-associated proteins 1A/1B light chain 3 beta 2, Microtubule-associated proteins 1A/1B light chain 3B, Microtubule-associated proteins 1A/1B light chain 3B-like, Microtubule-associated proteins 1A/1B light chain 3B-like protein, Mpl3, RP11-346K17.1, wu:fb60g11, zbs559, zgc:56434

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100359928, 643246, 64862, 67443, 81631

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
A6NCE7, Q62625, Q9CQV6, Q9GZQ8

Gene Symbols:
MAP1LC3B, MAP1LC3B2

Immunogen:
Recombinant MAP1LC3B protein, corresponding to amino acids 1-125 of Human MAP1LC3B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586105

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Antigen:
AMPK alpha-1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Prkaa1

Gene Alias:
5'-AMP-activated protein kinase alpha-1 catalytic subunit, 5'-AMP-activated protein kinase catalytic subunit alpha-1, 5'-AMP-activated protein kinase, catalytic alpha-1 chain, 63 kDa subunit, AAPK2, ACACA kinase, Acetyl-CoA carboxylase kinase, activated protein kinase, AI194361, AI450832, AL024255, AMP -activate kinase alpha 1 subunit, AMP activated protein kinase, AMP-activated protein kinase, alpha 1 catalytic subunit, AMP-activated protein kinase, catalytic, alpha-1, AMPK, AMPK 63 kDa subunit, AMPK alpha 1, AMPK alpha-1 chain, AMPK subunit alpha-1, AMPK subunit pAMPK, AMPK1, AMPK2, AMPKa1, AMPKalpha1, AMPK-alpha-2 chain, C130083N04Rik, HMGCR kinase, hydroxymethylglutaryl-CoA reductase kinase, MGC33776, MGC57364, pAMPK, PRKAA, Prkaa1, PRKAA2, protein kinase, protein kinase AMP-activated catalytic subunit alpha 1, protein kinase, AMP-activated, alpha 1 catalytic subunit, tau-protein kinase PRKAA1

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
105787, 5562, 65248

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 15mM sodium azide, pH 7.2

Gene Accession No.:
P54645, Q13131, Q5EG47

Gene Symbols:
Prkaa1

Immunogen:
Synthetic peptide, corresponding to amino acids 150-200 of Human AMPKalpha1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586106

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Antigen:
APAF1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
APAF1

Gene Alias:
6230400I06Rik, APAF1, APAF-1, Apaf1l, apoptotic peptidase activating factor 1, apoptotic protease activating factor 1, apoptotic protease-activating factor 1, CED4, DKFZp781B1145, fog, forebrain overgrowth, KIAA0413, mKIAA0413

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11783, 317, 78963

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O14727, O88879, Q9EPV5

Gene Symbols:
APAF1

Immunogen:
Synthetic peptide, corresponding to amino acids 301-350 of Human Apaf-1-ALT.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586107

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Antigen:
Protein APC

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Apc

Gene Alias:
adenomatosis polyposis coli, adenomatosis polyposis coli tumor suppressor, adenomatous polyposis coli, adenomatous polyposis coli protein, AI047805, APC, APC, WNT signaling pathway regulator, AU020952, AW124434, BTPS2, CC1, Deleted in polyposis 2.5, DP2, DP2.5, DP3, FAP, FPC, GS, mAPC, Min, multiple intestinal neoplasia, PPP1R46, Protein APC, protein phosphatase 1, regulatory subunit 46, RATAPC, truncated adenomatosis polyposis coli, WNT signaling pathway regulator

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11789, 24205, 324

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P25054, P70478, Q61315

Gene Symbols:
Apc

Immunogen:
Synthetic peptide, corresponding to the C-terminal of Human APC.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG