PIPA586125

CHK2 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

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Pack Size SKU Availability Price
Each of 1 PIPA586125-Each-of-1 In Stock ₹ 44,705.10

PIPA586125 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

CHK2

Classification

Polyclonal

Conjugate

Unconjugated

Gene

Chek2

Gene Alias

CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11200, 114212, 50883

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Immunohistochemistry (Paraffin)

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

O96017, Q9Z265

Gene Symbols

Chek2

Immunogen

Synthetic peptide, corresponding to amino acids 31-80 of Human Chk2.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • CHEK2 (CHK2) is a serine/threonine kinase and a component of the DNA damage checkpoint pathway
  • A mutation in CHK2 has been linked to cancer
  • CHK2 is activated by DNA damage and phosphorylates several modulators of cell cycle control including tumor suppressor proteins
  • In addition, Chk2 can phosphorylate BRCA1, allowing BRCA1 to restore survival after DNA damage
  • Chk2 is a putative tumor suppressor protein, with mutations in to the Chk2 gene linked to Li-Fraumeni syndrome, a familiar cancer usually associated with inherited mutations in TP53
  • Also, mutations in CHK2 are thought to confer a predisposition to sarcomas, breast cancer, and brain tumors.

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Show Difference

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Thermo Scientific

PIPA586125

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Antigen:
CHK2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Chek2

Gene Alias:
CDS1, cds1 homolog, Checkpoint kinase 2, Checkpoint like protein CHK2, checkpoint-like protein CHK2, Chek2, Chk2, Chk2 (phospho T68), Chk2 (pThr68), CHK2 checkpoint homolog, CHK2 checkpoint homolog (S. pombe), Chk2 phospho, Chk2 phospho T68, del9, EC 2.7.11.1, hCds1, HuCds 1, HuCds1, kinase Chk2, LFS2, OTTHUMP00000199044, OTTHUMP00000199045, OTTHUMP00000199064, OTTHUMP00000199115, OTTHUMP00000199116, phospho Chk2 (T68), phospho Thr68 Chk2, PP1425, protein kinase Chk2, Rad53, Rad53 homolog, RP11-436C9.1, Serine/threonine protein kinase Chk2, serine/threonine-protein kinase Chk2

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11200, 114212, 50883

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
O96017, Q9Z265

Gene Symbols:
Chek2

Immunogen:
Synthetic peptide, corresponding to amino acids 31-80 of Human Chk2.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586126

--


Antigen:
Collagen II

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Col2a1

Gene Alias:
alpha 1 type II procollagen, alpha 1 type IIA collagen, alpha 1 type IIA collagen precursor, alpha collagen type II, alpha-1 type II collagen, ANFH, AOM, arthroophthalmopathy, progressive (Stickler syndrome), cartilage collagen, CB11, CG2A1A, CGA, Chondrocalcin, COL11A3, Col2, Col2a, col2a1, Col2a-1, col2a1.L, col2a1a, col2a1-a, col2a1-b, Collagen 2, Collagen alpha-1(II) chain, collagen II, alpha-1 polypeptide, collagen type II (Col2A1) gene, enhancer region, collagen type II alpha 1 chain, collagen type IIA, collagen, type II, alpha 1, collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital), collagen, type II, alpha 1 L homeolog, COLLII, cyanogen bromide, Del1, disproportionate micromelia, Dmm, Lpk, M100856, MGC131516, pro alpha1 type II collagen, pro-alpha 1(II), pro-alpha-1 type II collagen, procollagen alpha 1(II), Procollagen II alpha 1, procollagen, type II, alpha 1, Rgsc856, SEDC, STL1, type II collagen, type II collagen cyanogen bromide fragment CB10, type II collogen cyanogen bromide fragment CB8, unnamed protein product, X-col II, xcol2a1, XELAEV_18013523mg

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1280, 12824, 25412

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P02458, P05539, P28481

Gene Symbols:
Col2a1

Immunogen:
Synthetic peptide, corresponding to amino acids 101-150 of Human COL2A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586127

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Antigen:
COL4A1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
COL4A1

Gene Alias:
alpha 1 type IV collagen, alpha1(IV) collagen, arresten, Bru, BSVD, COL4A1, Col4a-1, COL4A1 NC1 domain, collagen alpha-1(IV) chain, collagen IV, alpha-1 polypeptide, collagen of basement membrane, alpha-1 chain, collagen type IV alpha 1 chain, collagen, type IV, alpha 1, Del(8)44H, Del(8)Bru44H, procollagen, type IV, alpha 1, RATOR, Raw, retinal anterior wiring, Svc

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
1282, 12826, 290905

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P02462, P02463

Gene Symbols:
COL4A1

Immunogen:
Synthetic peptide, corresponding to amino acids 11-60 of Human COL4A1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA586128

--


Antigen:
TPL2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MAP3K8

Gene Alias:
augmented in rheumatoid arthritis 2, AURA2, Cancer Osaka thyroid oncogene, cancer Osaka thyroid, oncogene, CCOT, c-COT, COT, cot (cancer Osaka thyroid) oncogene, COT proto-oncogene serine/threonine-protein kinase, Cot/Tpl2, D17TPL2, EC 1.14.16.2, Est, Estf, Ewing sarcoma transformant, FLJ10486, M3K8, MAP3K 8, Map3k8, MEKK8, mitogen activated protein kinase kinase kinase 8, mitogen-activated protein kinase kinase kinase 8, Protein kinase cot, Proto-oncogene c-Cot, proto-oncogene serine/threoine protein kinase, serine/threonine kinase (Tpl-2), serine/threonine-protein kinase cot, TH isoform 3, TH isoform a, TH-4, TPL 2, Tpl2, TPL-2, Tumor progression locus 2, TY3H, TYH

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
116596, 1326, 26410

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P41279, Q07174, Q63562

Gene Symbols:
MAP3K8

Immunogen:
Synthetic peptide, corresponding to amino acids 250-300 of Human Cot.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG