PIPA586386
GRK2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586386-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586386 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
GRK2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
GRK2
Gene Alias
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
110355, 156, 25238
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P25098, P26817, Q99MK8
Gene Symbols
GRK2
Immunogen
Synthetic peptide, corresponding to amino acids 600-650 of Human GRK2.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- ADRBK1 (GRK2) is a serine/threonine kinase
- Many of the G protein-coupled receptors are known to be phosphorylated by G protein-dependent receptor kinases (GRKs)
- G protein-coupled receptor kinases (GRKs) are important regulators of G protein-coupled receptors(GPCRs)
- GRK2 (83 kDa), one of six members of this family that have been identified, is ubiquitously expressed in mammals
- After binding to their ligand and interacting with heterotrimeric G proteins, GPCRs (e.g., a2-adrenergic receptor) are phosphorylated by GRKs
- Internalization of the GPCRs, regulated by beta-arrestin-1, leads to activation of the Ras - Raf - ERK1&2 signaling pathway
- GRK2 activity is tightly controlled by different mechanisms including phosphorylation by kinases such as PKC, Src and ERK1&2, as well as interaction with various proteins
- ERK phosphorylates and thus inactivates GRK2 on serine 670 in a negative feedback mechanism.
Compare Similar Items
Show Difference
Antigen: GRK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: GRK2
Gene Alias: ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110355, 156, 25238
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P25098, P26817, Q99MK8
Gene Symbols: GRK2
Immunogen: Synthetic peptide, corresponding to amino acids 600-650 of Human GRK2.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
GRK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
GRK2
Gene Alias:
ADRBK1, Adrbk-1, adrenergic beta receptor kinase 1, adrenergic receptor kinase, beta 1, adrenergic, beta, receptor kinase 1, BARK, BARK1, Bark-1, beta ARK, Beta-adrenergic receptor kinase 1, beta-adrenergic receptor kinase 1 beta ARK1, beta-AR kinase-1, betaARK1, BETA-ARK1, beta-ARK-1, EC 2.7.1.126, G protein-coupled receptor kinase 2, G-protein coupled receptor kinase 2, G-protein-coupled receptor kinase 2, grk 2, Grk2, GRK-2
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110355, 156, 25238
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P25098, P26817, Q99MK8
Gene Symbols:
GRK2
Immunogen:
Synthetic peptide, corresponding to amino acids 600-650 of Human GRK2.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: APE1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: APEX1
Gene Alias: AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11792, 328, 79116
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P27695, P28352, P43138
Gene Symbols: APEX1
Immunogen: Synthetic peptide, corresponding to amino acids 190-240 of Human APEX1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
APE1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
APEX1
Gene Alias:
AP endonuclease 1, AP endonuclease class I, AP lyase, Ape, APE1, APEN, Apex, APEX nuclease, APEX nuclease (multifunctional DNA repair enzyme) 1, APEX nuclease 1, Apex1, apurinic/a, Apurinic/apy, apurinic/apyrimidinic (abasic) endonuclease, apurinic/apyrimidinic endodeoxyribonuclease 1, apurinic/apyrimidinic endonuclease, apurinic/apyrimidinic endonuclease 1, Apurinic-apyrimidinic endonuclease 1, APX, BAP 1, BAP1, deoxyribonuclease (apurinic or apyrimidinic), DNA-(apurinic or apyrimidinic site) endonuclease, DNA-(apurinic or apyrimidinic site) lyase, DNA-(apurinic or apyrimidinic site) lyase, mitochondrial, HAP1, protein REF-1, redox factor 1, redox factor-1, REF1, REF-1
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11792, 328, 79116
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P27695, P28352, P43138
Gene Symbols:
APEX1
Immunogen:
Synthetic peptide, corresponding to amino acids 190-240 of Human APEX1.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Cyclophilin F
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Ppif
Gene Alias: AW457192, cyclophilin 3, cyclophilin D, Cyclophilin F, CYP3, CypD, CyP-D, CyP-F, CyP-M, mitochondrial cyclophilin, mitochondrial Cyclophilin D, mitochondrial peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase F, peptidyl-prolyl cis-trans isomerase F, mitochondrial, peptidyl-prolyl cis-trans isomerase, mitochondrial, peptidylprolyl isomerase F, peptidylprolyl isomerase F (cyclophilin F), PPIase, PPIase F, PPIF, Rotamase F
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 10105, 105675, 282819
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P29117, P30405, Q99KR7
Gene Symbols: Ppif
Immunogen: Synthetic peptide, corresponding to amino acids 91-140 of Human Cyclophilin F.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Cyclophilin F
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Ppif
Gene Alias:
AW457192, cyclophilin 3, cyclophilin D, Cyclophilin F, CYP3, CypD, CyP-D, CyP-F, CyP-M, mitochondrial cyclophilin, mitochondrial Cyclophilin D, mitochondrial peptidyl-prolyl cis-trans isomerase, Peptidyl-prolyl cis-trans isomerase F, peptidyl-prolyl cis-trans isomerase F, mitochondrial, peptidyl-prolyl cis-trans isomerase, mitochondrial, peptidylprolyl isomerase F, peptidylprolyl isomerase F (cyclophilin F), PPIase, PPIase F, PPIF, Rotamase F
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
10105, 105675, 282819
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P29117, P30405, Q99KR7
Gene Symbols:
Ppif
Immunogen:
Synthetic peptide, corresponding to amino acids 91-140 of Human Cyclophilin F.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ACVR1B
Classification: Polyclonal
Conjugate: Unconjugated
Gene: ACVR1B
Gene Alias: 6820432J04, activin A receptor type 1B, activin A receptor type IB, activin A receptor, type 1B, activin A receptor, type IB, activin A receptor, type II-like kinase 4, activin receptor type IB, Activin receptor type-1B, activin receptor-like kinase 4, ACTRI, ActRIB, ActR-IB, ACVR1A, Acvr1b, ACVRLK2, ACVRLK4, ALK2, Alk4, ALK-4, FOP, Serine/threonine-protein kinase receptor R2, SKR1, SKR2, TSRI
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 11479, 29381, 91
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P36896, P80202, Q61271
Gene Symbols: ACVR1B
Immunogen: Synthetic peptide, corresponding to amino acids 100-150 of Human ACTR-IB.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ACVR1B
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
ACVR1B
Gene Alias:
6820432J04, activin A receptor type 1B, activin A receptor type IB, activin A receptor, type 1B, activin A receptor, type IB, activin A receptor, type II-like kinase 4, activin receptor type IB, Activin receptor type-1B, activin receptor-like kinase 4, ACTRI, ActRIB, ActR-IB, ACVR1A, Acvr1b, ACVRLK2, ACVRLK4, ALK2, Alk4, ALK-4, FOP, Serine/threonine-protein kinase receptor R2, SKR1, SKR2, TSRI
Host Species:
Rabbit
Purification Method:
Antigen affinity chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
11479, 29381, 91
Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin)
Concentration:
1 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.:
P36896, P80202, Q61271
Gene Symbols:
ACVR1B
Immunogen:
Synthetic peptide, corresponding to amino acids 100-150 of Human ACTR-IB.
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG