Apolipoprotein J Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA586452-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA586452 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Apolipoprotein J
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Clu
Gene Alias
AAG4, Aging associated protein 4, Aging-associated gene 4 protein, aging-associated protein 4, AI893575, apo j, Apo J a, Apo J alpha, Apo J b, Apo J beta, Apo J a, Apo J β, Apo Ja, Apo Jb, ApoJ, Apo-J, ApoJ a, ApoJ alpha, ApoJ b, ApoJ beta, ApoJ a, ApoJ β, ApoJa, ApoJalpha, ApoJb, ApoJbeta, Apolipoprotein J, CLI, Clu, CLU1, CLU2, clusterin, Clusterin alpha / beta chain, Clusterin alpha chain, Clusterin beta chain, Clustrin, Complement associated protein SP40, complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Complement cytolysis inhibitor b chain, complement lysis inhibitor, complement-associated protein SP-40,40, D14Ucla3, DAG, Dimeric acid glycoprotein, GP80, HGNC:2095, ku70-binding protein 1, Ku70-binding protein 1 (KUB1), KUB1, MGC24903, Msgp-2, NA1/NA2, RATTRPM2B, SGP2, Sgp-2, SP40, SP-40, Sugp-2, sulfated glycoprotein 2, Sulfated glycoprotein 2 (SGP2), testosterone repressed prostate message, testosterone repressed prostate message 2, Testosterone repressed prostate message 2 (TPRM2B), testosterone repressed prostate message-2, testosterone-repressed prostate message, testosterone-repressed prostate message 2, testostrone-repressed prostate message 2, Trpm2, TRPM-2, TRPM2B, Trpmb
Host Species
Rabbit
Purification Method
Antigen affinity chromatography
Regulatory Status
RUO
Gene ID (Entrez)
1191, 12759, 24854
Content And Storage
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form
Liquid
Applications
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration
1 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.
P05371, P10909, Q06890
Gene Symbols
Clu
Immunogen
Synthetic peptide, corresponding to amino acids C-terminus of Human Clusterin-alpha.
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Isoform 1 functions as extracellular chaperone that prevents aggregation of nonnative proteins
- Prevents stress-induced aggregation of blood plasma proteins
- Inhibits formation of amyloid fibrils by APP, APOC2, B2M, CALCA, CSN3, SNCA and aggregation-prone LYZ variants (in vitro)
- Does not require ATP
- Maintains partially unfolded proteins in a state appropriate for subsequent refolding by other chaperones, such as HSPA8/HSC70
- Does not refold proteins by itself
- Binding to cell surface receptors triggers internalization of the chaperone-client complex and subsequent lysosomal or proteasomal degradation
- Secreted isoform 1 protects cells against apoptosis and against cytolysis by complement
- Intracellular isoforms interact with ubiquitin and SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes and promote the ubiquitination and subsequent proteasomal degradation of target proteins
- Promotes proteasomal degradation of COMMD1 and IKBKB
- Modulates NF-kappa-B transcriptional activity
- Nuclear isoforms promote apoptosis
- Mitochondrial isoforms suppress BAX-dependent release of cytochrome c into the cytoplasm and inhibit apoptosis
- Plays a role in the regulation of cell proliferation.
Compare Similar Items
Show Difference
Antigen: Apolipoprotein J
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Clu
Gene Alias: AAG4, Aging associated protein 4, Aging-associated gene 4 protein, aging-associated protein 4, AI893575, apo j, Apo J a, Apo J alpha, Apo J b, Apo J beta, Apo J a, Apo J β, Apo Ja, Apo Jb, ApoJ, Apo-J, ApoJ a, ApoJ alpha, ApoJ b, ApoJ beta, ApoJ a, ApoJ β, ApoJa, ApoJalpha, ApoJb, ApoJbeta, Apolipoprotein J, CLI, Clu, CLU1, CLU2, clusterin, Clusterin alpha / beta chain, Clusterin alpha chain, Clusterin beta chain, Clustrin, Complement associated protein SP40, complement cytolysis inhibitor, Complement cytolysis inhibitor a chain, Complement cytolysis inhibitor b chain, complement lysis inhibitor, complement-associated protein SP-40,40, D14Ucla3, DAG, Dimeric acid glycoprotein, GP80, HGNC:2095, ku70-binding protein 1, Ku70-binding protein 1 (KUB1), KUB1, MGC24903, Msgp-2, NA1/NA2, RATTRPM2B, SGP2, Sgp-2, SP40, SP-40, Sugp-2, sulfated glycoprotein 2, Sulfated glycoprotein 2 (SGP2), testosterone repressed prostate message, testosterone repressed prostate message 2, Testosterone repressed prostate message 2 (TPRM2B), testosterone repressed prostate message-2, testosterone-repressed prostate message, testosterone-repressed prostate message 2, testostrone-repressed prostate message 2, Trpm2, TRPM-2, TRPM2B, Trpmb
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 1191, 12759, 24854
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P05371, P10909, Q06890
Gene Symbols: Clu
Immunogen: Synthetic peptide, corresponding to amino acids C-terminus of Human Clusterin-alpha.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: MLH1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Mlh1
Gene Alias: 1110035C23Rik, AI317206, AI325952, AI561766, COCA2, colon cancer, nonpolyposis type 2, DNA mismatch repair protein Mlh1, DNA mismatch repair protein Mlh1-like protein, FCC2, hMLH1, HNPCC, HNPCC2, I79_014127, MGC5172, mismatch repair protein 1, MLH1, MLH-1, mutL homolog 1, mutL homolog 1 (E. coli), mutL homolog 1, colon cancer, nonpolyposis type 2, mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli), mutL protein homolog 1
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 4292
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P40692
Gene Symbols: Mlh1
Immunogen: Synthetic peptide, corresponding to amino acids 450-500 of Human MLH1.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: MSH6
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MSH6
Gene Alias: AU044881, AW550279, cb326, DNA mismatch repair protein Msh6, g/T mismatch-binding protein, GTBP, GTMBP, hMSH6, HNPCC5, HSAP, LOC100360342, mismatch repair protein Msh6, Msh6, mutS (E. coli) homolog 6, MutS alpha 160kDa subunit, mutS homolog 6, mutS homolog 6 (E. coli), MutS protein homolog 6, MutS-alpha 160 kDa subunit, MutS-alpha 160kDa subunit, p160, rCG61559-like, Sperm associated protein, sperm-associated protein, wu:fb36c12
Host Species: Rabbit
Purification Method: Antigen affinity chromatography
Regulatory Status: RUO
Gene ID (Entrez): 17688, 2956
Content And Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.2
Gene Accession No.: P52701, P54276
Gene Symbols: MSH6
Immunogen: Synthetic peptide, corresponding to amino acids 350-400 of Human MSH6.
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
