PIPA586720

MYLK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586720-Each-of-1 In Stock ₹ 44,705.10

PIPA586720 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MYLK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYLK

Gene Alias

155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

4638

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Western Blot

Concentration

1 mg/mL

Formulation

PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.

Q15746

Gene Symbols

MYLK

Immunogen

Synthetic peptide, corresponding to amino acids 1750-1795 of Human MYLK.

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
  • MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
  • It is a central determinant in the development of vascular permeability and tissue edema formation
  • In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
  • MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
  • Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
  • Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
  • The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
  • MLCK is probably down-regulated by phosphorylation
  • The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586720

--


Antigen:
MYLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog, 9530072E15Rik, A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA, The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene., A930019C19Rik, AAT7, AW489456, kinase related protein, kinase-related protein, KRP, KRP/Telokin, MLCK, MLCK1, MLCK108, MLCK210, MSTP083, mylk, MYLK1, myosin light chain kinase, myosin light chain kinase, smooth muscle, Myosin light chain kinase, smooth muscle, deglutamylated form, myosin, light polypeptide kinase, nmMlck, smMLCK, smooth muscle myosin light chain kinase, smooth muscle myosin light chain kinase (61-kDa active fragment), smooth muscle myosin light chain kinase precursor (EC 2.7.2.37), telokin, unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
4638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q15746

Gene Symbols:
MYLK

Immunogen:
Synthetic peptide, corresponding to amino acids 1750-1795 of Human MYLK.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

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PIPA586721

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Antigen:
NPAS1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
NPAS1

Gene Alias:
basic-helix-loop-helix-PAS protein MOP5, BHLHE11, Class E basic helix-loop-helix protein 11, member of PAS protein 5, member of PAS superfamily 5, MOP5, neuronal PAS domain protein 1, neuronal PAS domain-containing protein 1, Neuronal PAS1, Npas1, PAS domain-containing protein 5, PASD5

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
18142, 308387, 4861

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P97459, Q99742

Gene Symbols:
NPAS1

Immunogen:
Synthetic peptide, corresponding to amino acids 486-531 of Human NPAS1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA586723

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Antigen:
PPP1R8

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PPP1R8

Gene Alias:
6330548N22Rik, activator of RNA decay, ARD1, ARD-1, AU044684, LOC100722083, NIPP1, NIPP-1, NIPP-1, nuclear inhibitor of protein phosphatase-1, Nuclear inhibitor of protein phosphatase 1, nuclear inhibitor of protein phosphatase-1 alpha, nuclear inhibitor of protein phosphatase-1 beta, nuclear subunit of PP-1, Ppp1r8, PRO2047, protein phosphatase 1 regulatory inhibitor subunit 8, protein phosphatase 1 regulatory subunit 8, protein phosphatase 1, regulatory (inhibitor) subunit 8, protein phosphatase 1, regulatory inhibitor subunit 8, protein phosphatase 1, regulatory subunit 8, RNase E

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
100336, 313030, 5511

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
Q12972, Q8R3G1

Gene Symbols:
PPP1R8

Immunogen:
Synthetic peptide, corresponding to amino acids 237-282 of Human NIPP1.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA586725

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Antigen:
PPP2R1B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ppp2r1b

Gene Alias:
2410091N08Rik, AI790395, PP2A A beta, PP2A -AR1 beta, PP2A subunit A isoform PR65-beta, PP2A subunit A isoform R1-beta, PP2A, subunit A, PR65-beta isoform, PP2A, subunit A, R1-beta isoform, PP2AA beta, PP2A-A beta, PP2A-Abeta, PP2A-APR65 beta, PPP2R1B, PR65B, protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform, protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform, protein phosphatase 2 regulatory subunit A, beta, protein phosphatase 2 scaffold subunit Abeta, protein phosphatase 2, regulatory subunit A, beta, protein phosphatase 2, structural/regulatory subunit A, beta, serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
315648, 5519, 73699

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.2

Gene Accession No.:
P30154, Q4QQT4, Q7TNP2

Gene Symbols:
Ppp2r1b

Immunogen:
Synthetic peptide, corresponding to amino acids 556-601 of Human PPP2R1B.

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG