PIPA586011

MYLK Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA586011-Each-of-1 In Stock ₹ 44,705.10

PIPA586011 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

MYLK

Classification

Polyclonal

Conjugate

Unconjugated

Gene

MYLK

Gene Alias

155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species

Rabbit

Purification Method

Antigen affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

107589, 4638

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Liquid

Applications

Flow Cytometry, Immunocytochemistry, Immunofluorescence

Concentration

1 mg/mL

Formulation

PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.

Q15746, Q6PDN3

Gene Symbols

MYLK

Immunogen

Synthetic peptide within Human MLCK aa 36-85

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse

Product Type

Antibody

Isotype

IgG

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Description

  • Rabbit Polyclonal Antibody MYLK (MLCK) is a serine/threonine kinase that phosphorylates myosin regulatory light chains to assist in the production of contractile activity (myosin-actin interaction)
  • MLCK is responsible for smooth muscle contraction via phosphorylation of a specific serine in the N-terminus of myosin light chains (MLC), an event that facilitates myosin interaction with actin filaments
  • It is a central determinant in the development of vascular permeability and tissue edema formation
  • In the nervous system it has been shown to control the growth initiation of astrocytic processes in culture and to participate in transmitter release at synapses formed between cultured sympathetic ganglion cells
  • MLCK acts as a critical participant in signaling sequences that result in fibroblast apoptosis
  • Smooth muscle and non-muscle isozymes are expressed in a wide variety of adult and fetal tissues and in cultured endothelium with qualitative expression appearing to be neither tissue- nor development-specific
  • Non-muscle isoform 2 is the dominant splice variant expressed in various tissues
  • The Telokin isoform, which binds calmodulin, has been found in a wide variety of adult and fetal tissues
  • MLCK is probably down-regulated by phosphorylation
  • The protein contains 1 fibronectin type III domain and 9 immunoglobulin-like C2-type domains.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA586011

--


Antigen:
MYLK

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
MYLK

Gene Alias:
155 kda myosin light chain kinase homolog; 9530072E15Rik; A clone isolated from a chicken gizzard cDNA library which has high homology with the 3'-end sequence of the chicken gizzard myosin light chain kinase (MLCK) cDNA; The 5'-leader seqeuence derives from the intronic sequence of the MLCK gene.; A930019C19Rik; AAT7; AW489456; kinase related protein; kinase-related protein; KRP; KRP/Telokin; MLCK; MLCK1; MLCK108; MLCK210; MSTP083; mylk; MYLK1; myosin light chain kinase; myosin light chain kinase, smooth muscle; Myosin light chain kinase, smooth muscle, deglutamylated form; myosin, light polypeptide kinase; nmMlck; smMLCK; smooth muscle myosin light chain kinase; smooth muscle myosin light chain kinase (61-kDa active fragment); smooth muscle myosin light chain kinase precursor (EC 2.7.2.37); telokin; unnamed protein product

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
107589, 4638

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunofluorescence

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q15746, Q6PDN3

Gene Symbols:
MYLK

Immunogen:
Synthetic peptide within Human MLCK aa 36-85

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586012

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Antigen:
Nestin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Nes

Gene Alias:
AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
10763, 18008

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P48681, Q6P5H2

Gene Symbols:
Nes

Immunogen:
Synthetic peptid within Human Nestin aa 1,271-1,320

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586013

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Antigen:
TSC2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TSC2

Gene Alias:
LAM; Nafld; OTTHUMP00000198394; PPP1R160; protein phosphatase 1, regulatory subunit 160; Rc; renal carcinoma; Tcs2; Tsc2; TSC4; Tuberin; tuberous sclerosis 2; tuberous sclerosis 2 homolog protein; tuberous sclerosis 2 protein; Tuberous sclerosis 2 protein homolog

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22084, 7249

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Immunocytochemistry, Immunohistochemistry

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
P49815, Q61037

Gene Symbols:
TSC2

Immunogen:
Synthetic peptide within Human TSC2 aa 1,758-1,807

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG

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PIPA586015

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Antigen:
PYGO2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
PYGO2

Gene Alias:
1190004M21Rik; mpygo2; PP7910; PYGO2; pygopus 2; pygopus family PHD finger 2; pygopus homolog 2; RGD1308535

Host Species:
Rabbit

Purification Method:
Antigen affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
68911, 90780

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Liquid

Applications:
Flow Cytometry, Western Blot

Concentration:
1 mg/mL

Formulation:
PBS with 0.2% BSA, 40% Glycerol and 0.05% sodium azide; pH 7.4

Gene Accession No.:
Q9BRQ0

Gene Symbols:
PYGO2

Immunogen:
Synthetic peptide within Human Pygopus aa 31-80

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse

Product Type:
Antibody

Isotype:
IgG