PIPA587375
Caspase 12 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587375-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA587375 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Caspase 12
Classification
Polyclonal
Conjugate
Unconjugated
Gene
CASP12
Gene Alias
CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
100506742, 12364, 156117
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Western Blot
Concentration
0.368 mg/mL
Formulation
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.
O08736, Q6UXS9, Q920D5
Gene Symbols
CASP12
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Caspase-12 (NP_0011779452)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: FNNRNCQSLK DKPKVIIMQA CRGNGAGIVW FTTDSGKASA DTHGRLLQGN ICNDAVTKAH VEKDFIAFKS STPHNVSWRH ETNGSVFISQ IIYYFREYSW S Positive Samples: Jurkat, Mouse lung, Mouse ovary, Mouse uterus, Rat lung Three distinct signaling pathways lead to programmed cell death (apoptosis)
- The death receptor and mitochondrion pathways are the mains, in which the key apoptotic proteases capase-8 and caspase-9, respectively, are involved
- The endoplasmic reticulum (ER) stress is the third apoptotic pathway and caspase-12 is involved
- Caspase-12 is localized to the ER but not to cytoplasm or mitochondrion
- Caspase-12 is activated by ER stress, including disruption of ER calcium homeostasis, and mediates ER stress-induced apoptosis
- Caspase-12 is co-localized to the ER with several proteins that are involved in Alzheimer's disease including -gamma-secretase presenilin and beta-amyloid precursor protein (APP)
- Caspase-12 mediates cytotoxicity induced by amyloid-beta
- Caspase-12 is ubiquitously expressed in mouse tissues.
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Antigen: Caspase 12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: CASP12
Gene Alias: CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 100506742, 12364, 156117
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.368 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: O08736, Q6UXS9, Q920D5
Gene Symbols: CASP12
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Caspase-12 (NP_0011779452)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Caspase 12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
CASP12
Gene Alias:
CASP12, CASP-12, CASP12P1, caspase 12, caspase 12 (gene/pseudogene), caspase 12 pseudogene 1, caspase-12, Inactive caspase-12, OTTMUSP00000045799, OTTMUSP00000045802, OTTMUSP00000045803, UNQ9415, UNQ9415/PRO34398
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
100506742, 12364, 156117
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.368 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
O08736, Q6UXS9, Q920D5
Gene Symbols:
CASP12
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human Caspase-12 (NP_0011779452)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: c-Raf
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Raf1
Gene Alias: 6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 110157, 5894
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.99 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P04049, Q99N57
Gene Symbols: Raf1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 190-350 of human Raf1 (NP_0028711)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
c-Raf
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Raf1
Gene Alias:
6430402F14Rik, AA990557, BB129353, CMD1NN, CRAF, C-RAF, C-Raf proto-oncogene, serine/threonine kinase, Craf1, Craf1 transforming, D830050J10Rik, EC 2.7.11.1, kinase Raf1, murine leukemia viral (v-raf-1) oncogene homolog 1 (3611-MSV), murine sarcoma 3611 oncogene 1, NS5, Oncogene RAF1, OTTHUMP00000207813, OTTHUMP00000209389, proto-oncogene c-RAF, RAF, raf proto-oncogene serine/threonine protein kinase, RAF proto-oncogene serine/threonine-protein kinase, RAF1, Raf-1, Raf-1 proto-oncogene, serine/threonine kinase, sarcoma 3611 oncogene, v-Raf, v-raf-1 leukemia viral oncogene 1, vraf1 murine le, v-raf-1 murine leukemia viral oncogene homolog 1, v-raf-1 murine leukemia viral oncogene-like protein 1, v-raf-leukemia viral oncogene 1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
110157, 5894
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.99 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P04049, Q99N57
Gene Symbols:
Raf1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 190-350 of human Raf1 (NP_0028711)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DOK4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DOK4
Gene Alias: docking protein 4, Dok4, Downstream of tyrosine kinase 4, insulin receptor substrate 5, IRS5, IRS-5
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114255, 361364, 55715
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.09 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q8TEW6, Q99KE3
Gene Symbols: DOK4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human DOK4 (NP_0605802)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DOK4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DOK4
Gene Alias:
docking protein 4, Dok4, Downstream of tyrosine kinase 4, insulin receptor substrate 5, IRS5, IRS-5
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114255, 361364, 55715
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.09 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q8TEW6, Q99KE3
Gene Symbols:
DOK4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-326 of human DOK4 (NP_0605802)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ERK2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MAPK1
Gene Alias: 9030612K14Rik, AA407128, AU018647, C78273, ERK, ERK2, ERK-2, ERT1, extracellular signal-regulated kinase 2, extracellular signal-regulated kinase-2, extracellular-signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk, MAPK 1, MAPK 2, Mapk1, MAPK2, mitogen activated protein kinase 1, mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, P42MAPK, p42-MAPK, Prkm1, PRKM2, protein tyrosine kinase ERK2
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116590, 26413, 5594
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Western Blot
Concentration: 2.29 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: P28482, P63085, P63086
Gene Symbols: MAPK1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_0027363)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ERK2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MAPK1
Gene Alias:
9030612K14Rik, AA407128, AU018647, C78273, ERK, ERK2, ERK-2, ERT1, extracellular signal-regulated kinase 2, extracellular signal-regulated kinase-2, extracellular-signal-regulated kinase 2, MAP kinase 1, MAP kinase 2, MAP kinase isoform p42, Mapk, MAPK 1, MAPK 2, Mapk1, MAPK2, mitogen activated protein kinase 1, mitogen-activated protein kinase 1, Mitogen-activated protein kinase 2, p38, p40, p41, p41mapk, P42MAPK, p42-MAPK, Prkm1, PRKM2, protein tyrosine kinase ERK2
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
116590, 26413, 5594
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Western Blot
Concentration:
2.29 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
P28482, P63085, P63086
Gene Symbols:
MAPK1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human ERK2 (NP_0027363)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG