PIPA587529

ErbB3 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA587529-Each-of-1 In Stock ₹ 44,705.10

PIPA587529 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

ErbB3

Classification

Polyclonal

Conjugate

Unconjugated

Gene

ERBB3

Gene Alias

avian erythroblastosis oncogene B 3, avian erythroblastosis oncogene B 3 receptor, C76256, c-erbB3, c-erbB-3, C-errB-3, erb-b2 receptor tyrosine kinase 3, ERBB3, Erbb-3, Erbb3r, erbB3-S, glial growth factor receptor, HER3, human epidermal growth factor receptor 3, LCCS2, MDA BF 1, MDA-BF-1, MGC88033, nuc-ErbB3, p180 ErbB3, p180-ErbB3, p45 sErbB3, p45-sErbB3, p85 sErbB3, p85-sErbB3, proto-oncogene-like protein c-ErbB-3, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-3, receptor tyrosine-protein kinase erbB-3, LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3, tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species

Rabbit

Purification Method

Affinity Chromatography

Regulatory Status

RUO

Gene ID (Entrez)

13867, 2065

Content And Storage

-20° C, Avoid Freeze/Thaw Cycles

Form

Liquid

Applications

Immunocytochemistry, Western Blot

Concentration

2.31 mg/mL

Formulation

PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.

P21860, Q61526

Gene Symbols

ERBB3

Immunogen

Recombinant fusion protein containing a sequence corresponding to amino acids 1275-1342 of human ErbB3/HER3 (NP_0019732)

Quantity

100 μL

Primary or Secondary

Primary

Target Species

Human, Mouse, Rat

Product Type

Antibody

Isotype

IgG

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Description

  • Immunogen sequence: DYAAMGACPA SEQGYEEMRA FQGPGHQAPH VHYARLKTLR SLEATDSAFD NPDYWHSRLF PKANAQRT Positive Samples: Mouse skeletal muscle, Mouse lung, Rat skeletal muscle; Cellular Location: Cell membrane, Single-pass type I membrane protein ErbB3 (c-erbB-3/HER-3) is a member of the type I family of growth factor receptors and binds to ligands in the heregulin family
  • ErbB3 is over-expressed in a variety of tumors in the prostate, bladder, breast, stomach, pancreas, and colon
  • Heregulin and EGF stimulate tyrosine phosphorylation of c-erbB-3 to different extents
  • The ErbB3 gene is located on the long arm of human chromosome 12 (12q13) and is transcribed into a 6
  • 2kb mRNA which is translated into a 160/180 kDa glycoprotein
  • The ErbB3 gene encodes a transmembrane receptor tyrosine kinase due to alternative splicing and forms heterodimers with other EGF receptor family members that have kinase activity
  • Heterodimerization leads to the activation of pathways that lead to cell proliferation or differentiation
  • Alternate transcriptional splice variants encoding different isoforms of ErbB3 have been characterized
  • One ErbB3 isoform lacks the intermembrane region, is secreted outside the cell, and acts to modulate the activity of the membrane-bound form
  • Additional splice variants have also been reported, but they have not been thoroughly characterized.

Compare Similar Items

Show Difference

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Thermo Scientific

PIPA587529

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Antigen:
ErbB3

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
ERBB3

Gene Alias:
avian erythroblastosis oncogene B 3, avian erythroblastosis oncogene B 3 receptor, C76256, c-erbB3, c-erbB-3, C-errB-3, erb-b2 receptor tyrosine kinase 3, ERBB3, Erbb-3, Erbb3r, erbB3-S, glial growth factor receptor, HER3, human epidermal growth factor receptor 3, LCCS2, MDA BF 1, MDA-BF-1, MGC88033, nuc-ErbB3, p180 ErbB3, p180-ErbB3, p45 sErbB3, p45-sErbB3, p85 sErbB3, p85-sErbB3, proto-oncogene-like protein c-ErbB-3, receptor tyrosine kinase, receptor tyrosine-protein kinase erbB-3, receptor tyrosine-protein kinase erbB-3, LOW QUALITY PROTEIN: receptor tyrosine-protein kinase erbB-3, tyrosine kinase-type cell surface receptor HER3, v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3, v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13867, 2065

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Western Blot

Concentration:
2.31 mg/mL

Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3

Gene Accession No.:
P21860, Q61526

Gene Symbols:
ERBB3

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1275-1342 of human ErbB3/HER3 (NP_0019732)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

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PIPA587534

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Antigen:
TRAF2

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TRAF2

Gene Alias:
AI325259, E3 ubiquitin-protein ligase TRAF2, MGC:45012, OTTHUMP00000064745, RING-type E3 ubiquitin transferase TRAF2, TNF receptor associated factor 2, Tnf receptor-associated factor 2, TRAF2, TRAP, TRAP3, tumor necrosis factor type 2 receptor associated protein 3, tumor necrosis factor type 2 receptor-associated protein 3

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
22030, 311786, 7186

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot

Concentration:
2.71 mg/mL

Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3

Gene Accession No.:
P39429, Q12933

Gene Symbols:
TRAF2

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TRAF2 (NP_0669612)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587537

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Antigen:
Cathepsin B

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Ctsb

Gene Alias:
amyloid precursor protein secretase, APP secretase, APPS, cathepsin B, Cathepsin B heavy chain, Cathepsin B light chain, Cathepsin B1, CB, CPSB, Ctsb, cysteine protease, RSG-2

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
13030, 1508, 64529

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.18 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P00787, P07858, P10605

Gene Symbols:
Ctsb

Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 18-339 of human Cathepsin B (NP_0018991)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

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PIPA587540

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Antigen:
RAP1A

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
RAP1A

Gene Alias:
AI848598, C21KG, G-22K, GTP-binding protein, GTP-binding protein smg p21A, GTP-binding protein SMG-P21A, KREV1, Krev-1, rap 1A, RAP1, RAP1A, RAP-1A, RAP1A, member of RAS oncogene family, RAS-related protein 1a, ras-related protein Krev-1, Ras-related protein Rap-1A, RAS-related protein-1a, SMGP21

Host Species:
Rabbit

Purification Method:
Affinity Chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
109905, 5906

Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles

Form:
Liquid

Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot

Concentration:
1.48 mg/mL

Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3

Gene Accession No.:
P62834, P62835

Gene Symbols:
RAP1A

Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 39-138 of human Rap1A (NP_0028751)

Quantity:
100 μL

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG