PIPA587879
B7-H4 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA587879-Each-of-1 | In Stock | ₹ 44,277.30 |
PIPA587879 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,277.30
GST (18%): ₹ 7,969.914
Total Price: ₹ 52,247.214
Antigen
B7-H4
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Vtcn1
Gene Alias
B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
242122, 295322, 79679
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
2.91 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q501W4, Q7TSP5, Q7Z7D3
Gene Symbols
Vtcn1
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human B7-H4/VTCN1 (NP_0789022)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: RTAVFADQVI VGNASLRLKN VQLTDAGTYK CYIITSKGKG NANLEYKTGA FSMPEVNVDY NASSETLRCE APRWFPQPTV VWASQVDQGA NFSEVSNTSF ELNSENVTMK VVSVLYNVTI NNTYSCMIEN DIAKATGDIK VTESEIKRRS HLQLLNSKAS L; Positive Samples: MCF-7, SKOV3, HeLa, 293T, B-cell, Mouse uterus, Rat thymus; Cellular Location: Cell membrane, Single-pass type I membrane protein B7-H4 (B7x, VTCN1) a costimulatory protein which is reported to function as a negative regulator of T-cell mediated immunity
- Although B7-H4 binds an unknown receptor, it is thought to deliver an inhibitory signal to T-cells preventing their proliferation, cell cycle progression and interleukin-2 production
- B7-H4 deficient mice are only minimally affected; suggesting B7-H4 is important in the fine tuning of the T-cell mediated immune response
- B7-H4 is expressed on activated T-cells, B-cells, monocytes and dendritic cells
- Aberrant expression has been associated with cancers of the lung, breast and ovary in humans
- B7-H4 is expressed primarily on the membrane of lymphoid cells, and as an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, it is involved in mediating cellular and humoral immune responses
- Overexpression of B7-H4 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumor cells suppress T cell immunity and facilitate tumor progression
- Further, VTCN1 may be a useful biomarker for the early detection of ovarian cancer and Renal Cell Carcinoma (RCC).
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Antigen: B7-H4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Vtcn1
Gene Alias: B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 242122, 295322, 79679
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.91 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q501W4, Q7TSP5, Q7Z7D3
Gene Symbols: Vtcn1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human B7-H4/VTCN1 (NP_0789022)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
B7-H4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Vtcn1
Gene Alias:
B7 family member, H4, B7 homolog 4, B7 superfamily member 1, B7h.5, B7H4, B7-H4, B7s1, B7x, BC032925, EMBL:AAH95842.1}, FLJ22418, immune costimulatory protein B7-H4, PRO1291, Protein B7S1, RGD1311204, RP11-229A19.4, t cell costimulatory molecule B7x, T-cell costimulatory molecule B7x, UNQ659/PRO1291, VCTN1, V-set domain containing T cell activation inhibitor 1, V-set domain containing T-cell activation inhibitor 1, V-set domain-containing T-cell activation inhibitor 1, Vtcn1, vtcn1 {ECO:0000312
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
242122, 295322, 79679
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.91 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q501W4, Q7TSP5, Q7Z7D3
Gene Symbols:
Vtcn1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 100-260 of human B7-H4/VTCN1 (NP_0789022)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: ZIP14
Classification: Polyclonal
Conjugate: Unconjugated
Gene: SLC39A14
Gene Alias: cig19, Factor for adipocyte differentiation 123, Fad123, FAD-123, HMNDYT2, Kiaa0062, LIV-1 subfamily of ZIP zinc transporter 4, LZT-Hs4, NET34, SLC39A14, solute carrier family 39 (metal ion transporter), member 14, solute carrier family 39 (zinc transporter), member 14, solute carrier family 39 member 14, Zinc transporter ZIP14, Zip14, ZIP-14, Zrt- and Cig19, Zrt- and Irt-like protein 14, Zrt-, Irt-like protein 14
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 213053, 23516, 306009
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.61 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q15043, Q75N73
Gene Symbols: SLC39A14
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 101-200 of human ZIP14 (NP_0011219031)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ZIP14
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
SLC39A14
Gene Alias:
cig19, Factor for adipocyte differentiation 123, Fad123, FAD-123, HMNDYT2, Kiaa0062, LIV-1 subfamily of ZIP zinc transporter 4, LZT-Hs4, NET34, SLC39A14, solute carrier family 39 (metal ion transporter), member 14, solute carrier family 39 (zinc transporter), member 14, solute carrier family 39 member 14, Zinc transporter ZIP14, Zip14, ZIP-14, Zrt- and Cig19, Zrt- and Irt-like protein 14, Zrt-, Irt-like protein 14
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
213053, 23516, 306009
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.61 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q15043, Q75N73
Gene Symbols:
SLC39A14
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 101-200 of human ZIP14 (NP_0011219031)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: TREML1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TREML1
Gene Alias: 5430401J17Rik, dJ238O23.3, GLTL1825, MGC119173, OTTHUMP00000017858, PRO3438, RGD1565175, Tlt1, TLT-1, TREM, TREML1, trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells, triggering receptor expressed on myeloid cells like 1, triggering receptor expressed on myeloid cells-like 1, triggering receptor expressed on myeloid cells-like 1c, triggering receptor expressed on myeloid cells-like 1d, triggering receptor expressed on myeloid cells-like 1e, triggering receptor expressed on myeloid cells-like protein 1, UNQ1825/PRO3438
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 501096, 71326
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 2.57 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q8K558
Gene Symbols: TREML1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_8354681)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TREML1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TREML1
Gene Alias:
5430401J17Rik, dJ238O23.3, GLTL1825, MGC119173, OTTHUMP00000017858, PRO3438, RGD1565175, Tlt1, TLT-1, TREM, TREML1, trem-like transcript 1 protein, Triggering receptor expressed on myeloid cells, triggering receptor expressed on myeloid cells like 1, triggering receptor expressed on myeloid cells-like 1, triggering receptor expressed on myeloid cells-like 1c, triggering receptor expressed on myeloid cells-like 1d, triggering receptor expressed on myeloid cells-like 1e, triggering receptor expressed on myeloid cells-like protein 1, UNQ1825/PRO3438
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
501096, 71326
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
2.57 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q8K558
Gene Symbols:
TREML1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 16-162 of human TREML1 (NP_8354681)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: COLEC12
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Colec12
Gene Alias: CLP1, CL-P1, COLEC12, Collectin placenta protein 1, collectin subfamily member 12, collectin sub-family member 12, collectin-12, hCL-P1, NSR2, Nurse cell scavenger receptor 2, Scara4, Scavenger receptor class A member 4, scavenger receptor class A, member 4, scavenger receptor with C-type lectin, Srcl
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 140792, 81035
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 1.48 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q5KU26, Q8K4Q8
Gene Symbols: Colec12
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_5690571)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
COLEC12
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Colec12
Gene Alias:
CLP1, CL-P1, COLEC12, Collectin placenta protein 1, collectin subfamily member 12, collectin sub-family member 12, collectin-12, hCL-P1, NSR2, Nurse cell scavenger receptor 2, Scara4, Scavenger receptor class A member 4, scavenger receptor class A, member 4, scavenger receptor with C-type lectin, Srcl
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
140792, 81035
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
1.48 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q5KU26, Q8K4Q8
Gene Symbols:
Colec12
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 60-270 of human COLEC12 (NP_5690571)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG