PIPA588650
ASAH2 Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA588650-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA588650 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
ASAH2
Classification
Polyclonal
Conjugate
Unconjugated
Gene
Asah2
Gene Alias
acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
114104, 54447, 56624
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.7 mg/mL
Formulation
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.
Q91XT9, Q9JHE3, Q9NR71
Gene Symbols
Asah2
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human ASAH2 (NP_0011374461)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: TATQTSPVPL TPESPLFQNF SGYHIGVGRA DCTGQVADIN LMGYGKSGQN AQGILTRLYS RAFIMAEPDG SNRTVFVSID IGMVSQRLRL EVLNRLQSKY GSLYRRDNVI LSGTHTHSGP AGYFQYTVFV IASEGFSNQT FQHMVTGILK SIDIAHTNMK PGKIFINKGN VDGVQINRSP YSYLQNPQSE RARYSSNTDK EMIVLKMVDL NGDDLGLISW FAIHPVSMNN SNHLVNSDNV GYASYLLEQE KNKGYLPGQG P; Positive Samples: 22Rv1, Mouse kidney, Rat kidney; Cellular Location: Cell membrane, Single-pass type II membrane protein Sphingolipids are hydrolyzed by ceramidases to yield sphingosine and fatty acids
- These ceramidases are classified according to the pH range that supports their optimal activity
- ASAH2 is a neutral ceramidase and key regulator of sphingolipid signaling metabolites at the cell surface, catalyzing the hydrolysis of the N-acyl linkage of ceramide at an optimal pH of 6.5-8.5
- ASAH2 is a type II integral membrane protein that can be cleaved to yield a soluble secreted protein and acts as a repressor of apoptosis both by reducing C16-ceramide, thereby preventing ceramide-induced apoptosis, and generating sphingosine
- Sphingosine exerts both mitogenic and apoptosis-inducing activities, and its phosphorylated form functions as an intra- and intercellular second messenger
- ASAH2 is ubiquitously expressed primarily expressed with higher levels in the intestine, kidney, skeletal muscle and heart
- Recent studies indicate that ASAH2 encoded neutral ceramidase is a key enzyme for the catabolism of dietary sphingolipids and regulates the levels of bioactive sphingolipid metabolites in the intestinal tract.
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Antigen: ASAH2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Asah2
Gene Alias: acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 114104, 54447, 56624
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.7 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q91XT9, Q9JHE3, Q9NR71
Gene Symbols: Asah2
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human ASAH2 (NP_0011374461)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
ASAH2
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Asah2
Gene Alias:
acylsphingosine deacylase 2, AI585898, Asah2, BCDase, hCD, HNAC1, LCDase, mitochondrial ceramidase, N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2, N-acylsphingosine amidohydrolase 2, NCDase, N-CDase, Neutral ceramidase, Neutral ceramidase soluble form, neutral/alkaline ceramidase, non-lysosomal ceramidase
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
114104, 54447, 56624
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.7 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q91XT9, Q9JHE3, Q9NR71
Gene Symbols:
Asah2
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 80-340 of human ASAH2 (NP_0011374461)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: MRPS22
Classification: Polyclonal
Conjugate: Unconjugated
Gene: MRPS22
Gene Alias: 28S ribosomal protein S22, mitochondrial, 3100002P07Rik, C3orf5, COXPD5, GIBT, GK002, mitochondrial ribosomal protein S22, Mitochondrial small ribosomal subunit protein mS22, MRPS22, MRP-S22, ribosomal protein, mitochondrial, S22, Rpms22, S22mt
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 56945, 64655, 683519
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.36 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: P82650, Q9CXW2
Gene Symbols: MRPS22
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MRPS22 (NP_0645761)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
MRPS22
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
MRPS22
Gene Alias:
28S ribosomal protein S22, mitochondrial, 3100002P07Rik, C3orf5, COXPD5, GIBT, GK002, mitochondrial ribosomal protein S22, Mitochondrial small ribosomal subunit protein mS22, MRPS22, MRP-S22, ribosomal protein, mitochondrial, S22, Rpms22, S22mt
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
56945, 64655, 683519
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.36 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
P82650, Q9CXW2
Gene Symbols:
MRPS22
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-360 of human MRPS22 (NP_0645761)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: Livin
Classification: Polyclonal
Conjugate: Unconjugated
Gene: BIRC7
Gene Alias: baculoviral IAP repeat containing 7, baculoviral IAP repeat-containing 7, baculoviral IAP repeat-containing 7 (livin), baculoviral IAP repeat-containing protein 7, Baculoviral IAP repeat-containing protein 7 30 kDa subunit, Baculoviral IAP repeat-containing protein 7 30kDa subunit, Birc7, E130019N06, KIAP, Kidney inhibitor of apoptosis protein, LIVIN, livin inhibitor of apoptosis, melanoma inhibitor of apoptosis protein, MLIAP, ML-IAP, RGD1562883, RING finger protein 50, RING-type E3 ubiquitin transferase BIRC7, RNF50, RP11-261N11.7, Truncated livin, UNQ5800/PRO19607/PRO21344
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 296468, 329581, 79444
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration: 1.56 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: A2AWP0, Q96CA5
Gene Symbols: BIRC7
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7 (NP_6474781)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
Livin
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
BIRC7
Gene Alias:
baculoviral IAP repeat containing 7, baculoviral IAP repeat-containing 7, baculoviral IAP repeat-containing 7 (livin), baculoviral IAP repeat-containing protein 7, Baculoviral IAP repeat-containing protein 7 30 kDa subunit, Baculoviral IAP repeat-containing protein 7 30kDa subunit, Birc7, E130019N06, KIAP, Kidney inhibitor of apoptosis protein, LIVIN, livin inhibitor of apoptosis, melanoma inhibitor of apoptosis protein, MLIAP, ML-IAP, RGD1562883, RING finger protein 50, RING-type E3 ubiquitin transferase BIRC7, RNF50, RP11-261N11.7, Truncated livin, UNQ5800/PRO19607/PRO21344
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
296468, 329581, 79444
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot
Concentration:
1.56 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
A2AWP0, Q96CA5
Gene Symbols:
BIRC7
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-265 of human BIRC7 (NP_6474781)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: DNAL1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: Dnal1
Gene Alias: 1700010H15Rik, AW121714, axonemal dynein light chain 1, C14orf168, CILD16, DNAL1, Dnalc1, dynein axonemal light chain 1, dynein light chain 1, axonemal, dynein, axonemal, light chain 1, E330027P08Rik, LC1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 105000, 685664, 83544
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q05A62, Q4LDG9
Gene Symbols: Dnal1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 41-190 of human DNAL1 (NP_1136152)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DNAL1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
Dnal1
Gene Alias:
1700010H15Rik, AW121714, axonemal dynein light chain 1, C14orf168, CILD16, DNAL1, Dnalc1, dynein axonemal light chain 1, dynein light chain 1, axonemal, dynein, axonemal, light chain 1, E330027P08Rik, LC1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
105000, 685664, 83544
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Western Blot
Concentration:
0.8 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q05A62, Q4LDG9
Gene Symbols:
Dnal1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 41-190 of human DNAL1 (NP_1136152)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG