PIPA595313

TREX1 Polyclonal Antibody, Invitrogen™

Manufacturer: Thermo Scientific

Select a Size

Pack Size SKU Availability Price
Each of 1 PIPA595313-Each-of-1 In Stock ₹ 44,705.10

PIPA595313 - Each of 1

₹ 44,705.10

In Stock

Quantity

1

Base Price: ₹ 44,705.10

GST (18%): ₹ 8,046.918

Total Price: ₹ 52,752.018

Antigen

TREX1

Classification

Polyclonal

Conjugate

Unconjugated

Gene

TREX1

Gene Alias

1661, 3' repair exonuclease 1, 3'-5' exonuclease TREX1, AGS1, AU041952, CRV, Deoxyribonuclease III, DNase III, DRN3, HERNS, RGD1309596, three prime exonuclease 1, three prime repair exonuclease 1, three-prime repair exonuclease 1, Trex1, trophoblast expressed 1

Host Species

Rabbit

Purification Method

Affinity chromatography

Regulatory Status

RUO

Gene ID (Entrez)

11277

Content And Storage

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form

Lyophilized

Applications

Western Blot

Concentration

500 μg/mL

Formulation

PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.

Q9NSU2

Gene Symbols

TREX1

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human TREX1 (156-185aa DDNLANLLLAFLRRQPQPWCLVAHNGDRYD).

Quantity

100 μg

Primary or Secondary

Primary

Target Species

Human

Product Type

Antibody

Isotype

IgG

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Description

  • Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL
  • Trex1 (ATRIP) is the major human 3' to 5' exonuclease which is required for checkpoint signaling after DNA damage
  • It is ubiquitously expressed, binds to single stranded DNA coated with replication protein A that accumulates at sites of DNA damage and recruits the ataxia telangiectasia and Rad3 related protein (ATR), a checkpoint kinase, to sites of DNA damage and replication stress
  • Trex1 is required for ATR expression
  • This gene uses two different open reading frames
  • The upstream ORF encodes proteins which interact with ATR and localize to intranuclear foci induced by DNA damage and are essential components of the DNA damage checkpoint
  • The downstream ORF encodes proteins with 3' to 5' exonuclease activity and may be a subunit of human DNA polymerase III
  • Multiple transcript variants encoding different isoforms have been found
  • Mutations in this gene result in Aicardi-Goutieres syndrome, chilblain lupus, and Cree encephalitis.

Compare Similar Items

Show Difference

Img

Thermo Scientific

PIPA595313

--


Antigen:
TREX1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TREX1

Gene Alias:
1661, 3' repair exonuclease 1, 3'-5' exonuclease TREX1, AGS1, AU041952, CRV, Deoxyribonuclease III, DNase III, DRN3, HERNS, RGD1309596, three prime exonuclease 1, three prime repair exonuclease 1, three-prime repair exonuclease 1, Trex1, trophoblast expressed 1

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11277

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q9NSU2

Gene Symbols:
TREX1

Immunogen:
A synthetic peptide corresponding to a sequence in the middle region of human TREX1 (156-185aa DDNLANLLLAFLRRQPQPWCLVAHNGDRYD).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595314

--


Antigen:
Transthyretin

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
TTR

Gene Alias:
AA408768, AI787086, Amyloidosis I, ATTR, carpal tunnel syndrome 1, CTS, CTS1, D17860, epididymis luminal protein 111, HEL111, HsT2651, Lr1, PALB, prealbumin, pre-albumin, prealbumin, amyloidosis type I, Tbpa, thyroxine-binding prealbumin, transthyretin, Tt, TTR

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
7276

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunohistochemistry (Paraffin), Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P02766

Gene Symbols:
TTR

Immunogen:
E.coli-derived human Prealbumin recombinant protein (Position: G21-E147).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595315

--


Antigen:
Arg3.1

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Arc

Gene Alias:
activity regulated cytoskeletal-associated protein, activity regulated cytoskeleton associated protein, activity-regulated cytoskeleton-associated protein, Activity-regulated gene 3.1 protein, activity-regulated gene 3.1 protein homolog, Arc, arc {ECO:0000312, ARC/ARG3.1, Arc3.1, arg3.1, Arg3.1/ARC, C86064, Growth factor ARC, hArc, KIAA0278, mArc, rg3.1, RGD:62037}

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
11838, 23237, 54323

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Immunocytochemistry, Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
Q63053, Q7LC44, Q9WV31

Gene Symbols:
Arc

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human Arc (332-366aa KLKRFLRHPLPKTLEQLIQRGMEVQDDLEQAAEPA).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Mouse, Rat

Product Type:
Antibody

Isotype:
IgG

Img

Thermo Scientific

PIPA595316

--


Antigen:
Cdc25C

Classification:
Polyclonal

Conjugate:
Unconjugated

Gene:
Cdc25c

Gene Alias:
CDC25, CDC25C, Cdc25m1, cell division cycle 25C, dual specificity phosphatase CDC25C, EC 3.1.3.48, mitosis inducer CDC25, M-phase inducer phosphatase 3, MPIP3, OTTHUMP00000159490, OTTHUMP00000224012, OTTHUMP00000224013, OTTHUMP00000224016, phosphotyrosine phosphatase, PPP1R60, protein phosphatase 1, regulatory subunit 60

Host Species:
Rabbit

Purification Method:
Affinity chromatography

Regulatory Status:
RUO

Gene ID (Entrez):
307511, 995

Content And Storage:
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Form:
Lyophilized

Applications:
Western Blot

Concentration:
500 μg/mL

Formulation:
PBS with 5MG BSA and 0.05MG sodium azide

Gene Accession No.:
P30307

Gene Symbols:
Cdc25c

Immunogen:
E.coli-derived human Cdc25C recombinant protein (Position: K175-P473).

Quantity:
100 μg

Primary or Secondary:
Primary

Target Species:
Human, Rat

Product Type:
Antibody

Isotype:
IgG