PIPA596163
DIABLO Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
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| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA596163-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA596163 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
DIABLO
Classification
Polyclonal
Conjugate
Unconjugated
Gene
DIABLO
Gene Alias
0610041G12Rik, 1700006L01Rik, AU040403, DFNA64, DIABLO, diablo homolog (Drosophila), diablo homolog, mitochondrial, diablo IAP-binding mitochondrial protein, diablo, IAP-binding mitochondrial protein, diablo-like protein, DIABLO-S, direct IAP binding protein with low PI, direct IAP-binding protein with low pI, FLJ10537, FLJ25049, hCG_1782202, Second mitochondria-derived activator of caspase, Smac, Smac protein, SMAC3
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
288753, 56616, 66593
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration
1.93 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
Q9JIQ3, Q9NR28
Gene Symbols
DIABLO
Immunogen
Recombinant fusion protein containing a sequence corresponding to amino acids 56-239 of human Smac/Diablo (NP_0639401)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Description
- Immunogen sequence: AVPIAQKSEP HSLSSEALMR RAVSLVTDST STFLSQTTYA LIEAITEYTK AVYTLTSLYR QYTSLLGKMN SEEEDEVWQV IIGARAEMTS KHQEYLKLET TWMTAVGLSE MAAEAAYQTG ADQASITARN HIQLVKLQVE EVHQLSRKAE TKLAEAQIEE LRQKTQEEGE ERAESEQEAY LRED Positive Samples: SW620, BT-474, Mouse spleen; Cellular Location: Mitochondrion DIABLO (smac), a mitochondrial protein, activates various forms of apoptosis
- This activation may be due to the neutralization of one or more members of the IAP family of apoptosis inhibitory proteins
- Smac exits the mitochondria and enter the cytosol during certain apoptosis triggered events
- Mitochondrial-mediated apoptosis is important in animal development and tissue homeostasis, with alterations resulting in a range of malignant disorders
- Upon apoptotic stimuli, the mitochondrial proteins cytochrome c and Smac/DIABLO are released into the cytosol
- The release of these proteins, however, occurs via different mechanisms
- Smac/DIABLO has also been found to play a key role in regulating the sensitization of cancer cells to apoptosis (both immune and drug-induced).
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Antigen: DIABLO
Classification: Polyclonal
Conjugate: Unconjugated
Gene: DIABLO
Gene Alias: 0610041G12Rik, 1700006L01Rik, AU040403, DFNA64, DIABLO, diablo homolog (Drosophila), diablo homolog, mitochondrial, diablo IAP-binding mitochondrial protein, diablo, IAP-binding mitochondrial protein, diablo-like protein, DIABLO-S, direct IAP binding protein with low PI, direct IAP-binding protein with low pI, FLJ10537, FLJ25049, hCG_1782202, Second mitochondria-derived activator of caspase, Smac, Smac protein, SMAC3
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 288753, 56616, 66593
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration: 1.93 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: Q9JIQ3, Q9NR28
Gene Symbols: DIABLO
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 56-239 of human Smac/Diablo (NP_0639401)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
DIABLO
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
DIABLO
Gene Alias:
0610041G12Rik, 1700006L01Rik, AU040403, DFNA64, DIABLO, diablo homolog (Drosophila), diablo homolog, mitochondrial, diablo IAP-binding mitochondrial protein, diablo, IAP-binding mitochondrial protein, diablo-like protein, DIABLO-S, direct IAP binding protein with low PI, direct IAP-binding protein with low pI, FLJ10537, FLJ25049, hCG_1782202, Second mitochondria-derived activator of caspase, Smac, Smac protein, SMAC3
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
288753, 56616, 66593
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot
Concentration:
1.93 mg/mL
Formulation:
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.:
Q9JIQ3, Q9NR28
Gene Symbols:
DIABLO
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 56-239 of human Smac/Diablo (NP_0639401)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: AIF
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AIFM1
Gene Alias: AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 26926, 83533, 9131
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration: 0.58 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: O95831, Q9JM53, Q9Z0X1
Gene Symbols: AIFM1
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_0041991)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
AIF
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
AIFM1
Gene Alias:
AG1, AGR1, Aif, AIFM1, AIFsh2, apoptosis inducing factor mitochondria associated 1, apoptosis inducing factor, mitochondria associated 1, apoptosis-inducing factor 1, mitochondrial, apoptosis-inducing factor, mitochondrion-associated 1, apoptosis-inducing factor, mitochondrion-associated, 1, CMT2D, CMTX4, COWCK, COXPD6, DFNX5, ER protein 18, ER protein 19, ERP18, ERP19, hAG-1, harlequin, Hq, hTLP19, MGC111425, mitochondrial apoptosis-inducing factor 1, NADMR, NAMSD, pcd8, PDCD8, PDIA16, programmed cell death 8 (apoptosis-inducing factor), programmed cell death protein 8, RP3-438D16.2, striatal apoptosis-inducing factor, testicular secretory protein Li 4, TLP19, UNQ713/PRO1376
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
26926, 83533, 9131
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunocytochemistry, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunohistochemistry (Paraffin)
Concentration:
0.58 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
O95831, Q9JM53, Q9Z0X1
Gene Symbols:
AIFM1
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 334-613 of human AIF (NP_0041991)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG
Antigen: PDCD4
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PDCD4
Gene Alias: D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 18569, 27250
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 0.3 mg/mL
Formulation: PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.: Q53EL6, Q61823
Gene Symbols: PDCD4
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse
Product Type: Antibody
Isotype: IgG
Antigen:
PDCD4
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
PDCD4
Gene Alias:
D19Ucla1, death up-regulated gene protein, death-upregulated, Dug, H731, Ma3, MGC33046, MGC33047, Neoplastic transformation inhibitor protein, nuclear antigen H731, Nuclear antigen H731-like, Pdcd4, programmed cell death 4, programmed cell death 4 (neoplastic transformation inhibitor), programmed cell death protein 4, Protein 197/15a, protein MA-3, RP11-348N5.4, Tis, topoisomerase-inhibitor suppressed protein
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
18569, 27250
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
0.3 mg/mL
Formulation:
PBS with 50% glycerol and 0.02% sodium azide, pH 7.3
Gene Accession No.:
Q53EL6, Q61823
Gene Symbols:
PDCD4
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human PDCD4 (NP_0552712)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse
Product Type:
Antibody
Isotype:
IgG
Antigen: TBK1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: TBK1
Gene Alias: 1200008B05Rik, AI462036, AW048562, FLJ11330, FTDALS4, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, serine/threonine protein kinase TBK1, serine/threonine-protein kinase TBK1, T2K, TANK binding kinase 1, TANK-binding kinase 1, tbk, TBK1
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 29110, 299827, 56480
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Immunohistochemistry (Paraffin), Western Blot
Concentration: 2.98 mg/mL
Formulation: PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.: Q9UHD2, Q9WUN2
Gene Symbols: TBK1
Immunogen: A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_0373861)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen:
TBK1
Classification:
Polyclonal
Conjugate:
Unconjugated
Gene:
TBK1
Gene Alias:
1200008B05Rik, AI462036, AW048562, FLJ11330, FTDALS4, NAK, NF-kappa-B-activating kinase, NF-kB-activating kinase, serine/threonine protein kinase TBK1, serine/threonine-protein kinase TBK1, T2K, TANK binding kinase 1, TANK-binding kinase 1, tbk, TBK1
Host Species:
Rabbit
Purification Method:
Affinity Chromatography
Regulatory Status:
RUO
Gene ID (Entrez):
29110, 299827, 56480
Content And Storage:
-20° C, Avoid Freeze/Thaw Cycles
Form:
Liquid
Applications:
Immunohistochemistry (Paraffin), Western Blot
Concentration:
2.98 mg/mL
Formulation:
PBS with 50% glycerol and 0.05% ProClin 300, pH 7.3
Gene Accession No.:
Q9UHD2, Q9WUN2
Gene Symbols:
TBK1
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 500-600 of human TBK1/NAK (NP_0373861)
Quantity:
100 μL
Primary or Secondary:
Primary
Target Species:
Human, Mouse, Rat
Product Type:
Antibody
Isotype:
IgG