Phospho-MYPT1 (Ser668) Polyclonal Antibody, Invitrogen™
Manufacturer: Thermo Scientific
Select a Size
| Pack Size | SKU | Availability | Price |
|---|---|---|---|
| Each of 1 | PIPA597418-Each-of-1 | In Stock | ₹ 44,705.10 |
PIPA597418 - Each of 1
In Stock
Quantity
1
Base Price: ₹ 44,705.10
GST (18%): ₹ 8,046.918
Total Price: ₹ 52,752.018
Antigen
Phospho-MYPT1 (Ser668)
Classification
Polyclonal
Conjugate
Unconjugated
Gene
PPP1R12A
Gene Alias
1200015F06Rik, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, 130 kDa regulatory subunit of myosin phosphatase, 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133), 5730577I22Rik, AA792106, AV099298, D10Ertd625e, hypothetical protein, I79_016312, LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A, M110, M130, M130 of smooth muscle myosin phosphatase, MBS, MBSP, myosin binding subunit, myosin phosphatase target subunit 1, myosin phosphatase, target subunit 1, myosin phosphatase-targeting subunit 1, myosin-binding subunit of myosin phosphatase, Mypt1, PP-1M, PP1M M110 subunit, PP1M subunit M110, Ppp1r12a, Protein phosphatase 1 regulatory subunit 12A, protein phosphatase 1, regulatory (inhibitor) subunit 12A, protein phosphatase 1, regulatory subunit 12A, protein phosphatase 1M 110 kda regulato
Host Species
Rabbit
Purification Method
Affinity Chromatography
Regulatory Status
RUO
Gene ID (Entrez)
116670, 17931, 4659
Content And Storage
-20° C, Avoid Freeze/Thaw Cycles
Form
Liquid
Applications
Western Blot
Concentration
0.8 mg/mL
Formulation
PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.
O14974, Q10728, Q9DBR7
Gene Symbols
PPP1R12A
Immunogen
A synthetic phosphorylated peptide around S668 of human PPP1R12A (NP_0011373571)
Quantity
100 μL
Primary or Secondary
Primary
Target Species
Human, Mouse, Rat
Product Type
Antibody
Isotype
IgG
Related Products
Description
- Immunogen sequence: RRSYL; Positive Samples: HeLa, C6; Cellular Location: Cytoplasm Myosin phosphatase target subunit 1, which is also called the myosin-binding subunit of myosin phosphatase, is one of the subunits of myosin phosphatase
- Myosin phosphatase regulates the interaction of actin and myosin downstream of the guanosine triphosphatase Rho
- The small guanosine triphosphatase Rho is implicated in myosin light chain (MLC) phosphorylation, which results in contraction of smooth muscle and interaction of actin and myosin in nonmuscle cells
- The guanosine triphosphate (GTP)-bound, active form of RhoA (GTP
- RhoA) specifically interacted with the myosin-binding subunit (MBS) of myosin phosphatase, which regulates the extent of phosphorylation of MLC
- Rho-associated kinase (Rho-kinase), which is activated by GTP
- RhoA, phosphorylated MBS and consequently inactivated myosin phosphatase
- Overexpression of RhoA or activated RhoA in NIH 3T3 cells increased phosphorylation of MBS and MLC
- Thus, Rho appears to inhibit myosin phosphatase through the action of Rho-kinase
- Several transcript variants encoding different isoforms have been found for this gene.
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Antigen: Phospho-MYPT1 (Ser668)
Classification: Polyclonal
Conjugate: Unconjugated
Gene: PPP1R12A
Gene Alias: 1200015F06Rik, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase, 130 kDa myosin-binding subunit of smooth muscle myosin phophatase (M130), 130 kDa myosin-binding subunit of smooth muscle myosin phosphatase, 130 kDa regulatory subunit of myosin phosphatase, 133kDa myosin-binding subunit of smooth muscle myosin phosphatase (M133), 5730577I22Rik, AA792106, AV099298, D10Ertd625e, hypothetical protein, I79_016312, LOW QUALITY PROTEIN: protein phosphatase 1 regulatory subunit 12A, M110, M130, M130 of smooth muscle myosin phosphatase, MBS, MBSP, myosin binding subunit, myosin phosphatase target subunit 1, myosin phosphatase, target subunit 1, myosin phosphatase-targeting subunit 1, myosin-binding subunit of myosin phosphatase, Mypt1, PP-1M, PP1M M110 subunit, PP1M subunit M110, Ppp1r12a, Protein phosphatase 1 regulatory subunit 12A, protein phosphatase 1, regulatory (inhibitor) subunit 12A, protein phosphatase 1, regulatory subunit 12A, protein phosphatase 1M 110 kda regulato
Host Species: Rabbit
Purification Method: Affinity Chromatography
Regulatory Status: RUO
Gene ID (Entrez): 116670, 17931, 4659
Content And Storage: -20° C, Avoid Freeze/Thaw Cycles
Form: Liquid
Applications: Western Blot
Concentration: 0.8 mg/mL
Formulation: PBS with 50% glycerol and 0.01% thimerosal, pH 7.3
Gene Accession No.: O14974, Q10728, Q9DBR7
Gene Symbols: PPP1R12A
Immunogen: A synthetic phosphorylated peptide around S668 of human PPP1R12A (NP_0011373571)
Quantity: 100 μL
Primary or Secondary: Primary
Target Species: Human, Mouse, Rat
Product Type: Antibody
Isotype: IgG
Antigen: A2ML1
Classification: Polyclonal
Conjugate: Unconjugated
Gene: A2ML1
Gene Alias: A2ML1, alpha-2-macroglobulin like 1, alpha-2-macroglobulin-like 1, alpha-2-macroglobulin-like protein 1, BC048546, C3 and PZP-like alpha-2-macroglobulin domain-containing protein 9, C3 and PZP-like, alpha-2-macroglobulin domain containing 9, cDNA sequence BC048546, CPAMD9, Ovos, Ovostatin homolog
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 144568
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Immunohistochemistry (Paraffin), Western Blot
Concentration: 4 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: A8K2U0
Gene Symbols: A2ML1
Immunogen: Recombinant Human Alpha-2-macroglobulin-like protein 1 protein (625-751AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
Antigen: AADACL2
Classification: Polyclonal
Conjugate: Unconjugated
Gene: AADACL2
Gene Alias: Aadacl2, ADCL2, arylacetamide deacetylase like 2, arylacetamide deacetylase-like 2, EG639634, MGC72001, RGD1563197
Host Species: Rabbit
Purification Method: Protein G
Regulatory Status: RUO
Gene ID (Entrez): 344752
Content And Storage: -20°C or -80°C if preferred
Form: Liquid
Applications: ELISA, Western Blot
Concentration: 2 mg/mL
Formulation: PBS with 50% glycerol and 0.03% ProClin 300, pH 7.4
Gene Accession No.: Q6P093
Gene Symbols: AADACL2
Immunogen: Recombinant Human Arylacetamide deacetylase-like 2 protein (203-401AA)
Quantity: 100 μg
Primary or Secondary: Primary
Target Species: Human
Product Type: Antibody
Isotype: IgG
